Detailed information NTG0121931

Bioinformatically predicted

Overview

• Name: chiS
• Type: Regulator
• Locus tag: EN18_RS00145
• Genome accession: NZ_CP007634
• Coordinates: 37900..41433 (-)
• Length: 1177 a.a.
• NCBI ID: WP_001883436.1
• Uniprot ID: -
• Organism: Vibrio cholerae strain 2012EL-2176
• Function: chitin sensor (predicted from homology) Competence regulation

Genomic Context

Location: 32900..46433

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EN18_RS00125 (EN18_06040)	-	33135..34160 (-)	1026	WP_000646270.1	ABC transporter permease	-
EN18_RS00130 (EN18_06045)	-	34163..35149 (-)	987	WP_000540337.1	ABC transporter permease	-
EN18_RS00135 (EN18_06050)	-	35319..36989 (-)	1671	WP_000880698.1	ABC transporter substrate-binding protein	-
EN18_RS00145 (EN18_06055)	chiS	37900..41433 (-)	3534	WP_001883436.1	two-component system sensor histidine kinase ChiS	Regulator
EN18_RS00150 (EN18_06060)	rsmC	41497..42519 (-)	1023	WP_001183380.1	16S rRNA (guanine(1207)-N(2))-methyltransferase RsmC	-
EN18_RS00155 (EN18_06065)	-	42592..43677 (-)	1086	WP_001290813.1	AI-2E family transporter	-
EN18_RS00165 (EN18_06070)	hemL	43931..45229 (-)	1299	WP_000167257.1	glutamate-1-semialdehyde 2,1-aminomutase	-
EN18_RS00175 (EN18_06080)	erpA	45513..45854 (+)	342	WP_000005741.1	iron-sulfur cluster insertion protein ErpA	-

Sequence

Protein

• Length: 1177 a.a.
• Molecular weight: 133134.30 Da
• Isoelectric Point: 6.8941

>NTDB_id=121931 EN18_RS00145 WP_001883436.1 37900..41433(-) (chiS) [Vibrio cholerae strain 2012EL-2176]
MRLCPRFSLDLLVKVKKLVNFVTLGFSCLSPTHAWRSPQSFTESNTLIMFRFYRKQKFKRLQNTLMAAFLALSIIPLTIT
ALFFLHSHSKDLEQQSTSYLVSVRDNKQQQVIDYMMAKESEVMGFVRSELAYASGGRFYGLVNAFQRLDVSIEAAREHAQ
QRYITGSGDQIKTSVLPQSSSYVGSERYRLLHKRYHWAYLELLKRSDFDDILLVDIDGNVVYSIYKYDNFGTNLLTGKYQ
DTNLGHTFKRLEQTVNEQRKTNEDFTPVVISDFVQEDGKQYAWLGAPIIQQGYLHSYAMFRLPSNAITKLIAEGSSNPSM
QTILVGQDHRSRTLTSAEIAVEKSKAVVDLALSGKRAVGTYTNTDGEQIIAAYAPINLKNIHWALVVELPEKEAFARVRQ
LEKLFVFAMLTAIVLVVIASHYLSNFITSPLLKLTWAAERVSAGDLDEAMINTERKDEIGRLAVSFERMQRSIREKISLI
KSQNKELESNLLIIRKQNDELQLANKLKDEFLATTSHELRTPLHGMIGIAEALISGANGPISAAHKYQLDIIISSGQRLA
TLVDDLLDYHKMRYGALDIQRCAVDLSSATRLVLELSHHLLGKKTLRIINQVSEQPVWVSADPQRLEQVLYNLIGNAIKY
TSEGKIVISATYIDDKVRVQVVDTGQGIPAEQLEHIFEPLIQAGHDASRYRQGAGLGLSISRQLIELMHGTLYVSSQPMV
GTTFSFTLPLASEEEIAQARLTELPHFQAPEVLDSELPEQSNLPENEHGPLLLVADDEPVNLRVLDSFLRLEGYRVHTAQ
DGHQVLEAIKREKPELVLLDIMMPGMSGYQVCEKLRQTYDHAELPIIMLTALNQSDDRVRGFEAGANDYLSKPFNKQELA
ARIVAHLTASKAELRRIENAQLQKELKHRAMVEASLLETQGRLLEQLESAPEAILCVKEGNKVRFANEAAARLFRRTPEQ
LKRSNAEELIAPKFLNIEQEHYCGNIDVYVDDVRQHLSADVLRLPQGSGLQAMYIFNVGGSVNAARIHNLETAVEALSSY
AFEGDKDKLQKLKELGGEFTRLADKASGEYQSKQDLMRAVLVEAMTSALNYWERVSGQSKFTFAEQSGLWRVYLDRSTLQ
TRTLDKYLRIETLPKTPRWRTVLNSLDYILEHCKEAGPERTHIEMQRDKLQKLLTSE

Nucleotide

• Length: 3534 bp

>NTDB_id=121931 EN18_RS00145 WP_001883436.1 37900..41433(-) (chiS) [Vibrio cholerae strain 2012EL-2176]
TTGCGTCTATGCCCACGCTTTAGCTTGGACTTACTTGTCAAAGTAAAAAAACTCGTTAATTTCGTTACTTTAGGTTTTTC
TTGTCTATCACCCACTCATGCTTGGCGATCGCCGCAGAGTTTCACCGAAAGTAACACCTTAATTATGTTTAGGTTCTATC
GAAAACAAAAATTCAAACGCCTGCAAAATACCTTGATGGCTGCGTTTTTGGCCCTCAGCATTATTCCTTTGACCATTACT
GCGTTGTTTTTCCTACATTCACACAGTAAAGATCTGGAGCAGCAGAGCACTTCTTACCTCGTTTCTGTTCGGGATAATAA
ACAGCAACAGGTCATCGACTACATGATGGCCAAAGAGTCGGAAGTGATGGGTTTTGTTCGCTCCGAGCTGGCTTATGCCA
GTGGCGGGCGTTTTTATGGTCTGGTGAATGCTTTCCAGCGTTTAGACGTCAGTATTGAAGCGGCTCGTGAACATGCTCAG
CAGCGCTATATCACCGGATCGGGTGACCAAATAAAAACCTCGGTGCTCCCCCAATCAAGCAGCTACGTGGGCAGTGAACG
CTATCGACTGCTGCATAAACGCTACCACTGGGCTTACTTAGAACTGCTGAAACGGTCGGACTTTGATGACATTTTATTGG
TCGATATTGATGGCAACGTCGTTTATTCGATTTATAAATACGACAATTTTGGCACCAACTTATTAACGGGCAAATACCAA
GACACCAATCTAGGCCATACCTTCAAGCGTTTAGAACAAACGGTCAATGAACAGCGCAAAACCAACGAAGATTTCACCCC
TGTCGTGATTTCTGATTTCGTACAAGAGGATGGTAAACAATACGCTTGGCTTGGCGCACCGATTATTCAGCAAGGCTACT
TGCATAGTTACGCGATGTTCCGCTTACCAAGCAATGCGATCACCAAACTCATCGCAGAAGGCAGTAGCAATCCTTCGATG
CAAACCATTCTAGTGGGACAAGATCACCGCTCAAGAACCTTAACTTCCGCCGAAATTGCGGTTGAAAAAAGTAAAGCTGT
GGTCGATTTAGCCTTATCGGGCAAACGCGCCGTAGGCACTTACACCAATACCGATGGTGAACAGATCATCGCGGCCTACG
CACCGATCAATTTGAAAAATATCCATTGGGCTCTGGTGGTTGAACTGCCAGAGAAAGAAGCGTTTGCTCGCGTTCGTCAG
TTAGAGAAACTGTTTGTTTTTGCGATGTTGACGGCTATCGTCTTAGTGGTCATCGCCTCGCATTACCTTTCCAATTTCAT
TACCTCACCGCTTTTGAAGCTGACATGGGCAGCCGAACGTGTTTCGGCAGGCGATCTTGATGAAGCCATGATCAATACCG
AACGCAAAGATGAAATTGGCCGCTTGGCGGTCAGTTTTGAGCGTATGCAGCGTTCCATTCGCGAAAAAATATCGCTGATC
AAATCGCAAAATAAAGAGTTAGAGAGCAACTTACTGATCATTCGTAAGCAAAACGATGAGTTACAGCTAGCGAATAAGCT
AAAAGATGAGTTCCTCGCGACCACATCACATGAATTACGCACCCCATTGCATGGCATGATTGGTATTGCCGAAGCCCTGA
TCTCGGGGGCAAATGGCCCGATTTCAGCAGCGCACAAGTATCAACTCGACATCATTATCAGCAGTGGGCAGCGCTTGGCG
ACTCTGGTTGATGATCTACTCGATTACCACAAAATGCGCTATGGCGCGCTGGATATTCAAAGGTGTGCCGTCGATTTATC
GAGCGCTACGCGCTTAGTCTTGGAGCTTTCTCACCATTTACTTGGCAAGAAAACGCTGCGCATTATTAATCAAGTCTCAG
AACAACCGGTCTGGGTTTCTGCGGATCCTCAACGCTTAGAGCAAGTCCTGTATAACTTGATCGGCAATGCCATTAAGTAC
ACTTCCGAAGGCAAAATTGTTATCTCCGCAACCTATATTGACGATAAAGTGCGCGTGCAGGTGGTGGATACAGGTCAAGG
GATTCCGGCAGAACAACTGGAGCACATCTTTGAGCCATTGATTCAAGCGGGCCATGATGCGAGTCGCTATCGCCAAGGCG
CAGGACTCGGGCTTTCCATCAGTCGTCAGTTAATCGAATTGATGCACGGCACTCTCTACGTAAGTAGTCAGCCGATGGTT
GGCACTACCTTTAGCTTCACGCTGCCTCTGGCGAGCGAAGAAGAGATTGCTCAAGCGCGCTTGACCGAACTCCCCCACTT
CCAAGCACCGGAAGTGTTGGATTCTGAACTGCCCGAGCAAAGCAACTTACCCGAAAATGAACATGGCCCACTTCTGTTGG
TCGCCGATGATGAACCAGTCAACCTGCGTGTGCTGGACAGCTTTTTACGTCTTGAAGGTTATCGCGTACATACCGCGCAA
GATGGCCATCAAGTACTTGAAGCAATTAAACGTGAAAAACCTGAATTGGTGTTACTCGACATCATGATGCCAGGCATGAG
CGGTTATCAAGTGTGTGAAAAACTTCGACAAACTTACGACCACGCTGAACTGCCTATTATTATGCTGACGGCTCTCAACC
AGTCTGATGACCGGGTACGAGGGTTTGAAGCTGGAGCCAATGACTACTTATCCAAACCATTCAACAAACAAGAGCTGGCC
GCGCGCATTGTCGCTCACCTCACGGCGAGCAAAGCCGAACTGCGCCGCATTGAGAATGCCCAACTGCAAAAAGAGTTGAA
ACATCGCGCTATGGTAGAAGCGAGCCTATTGGAAACCCAAGGCCGATTATTGGAACAGTTAGAATCTGCGCCAGAAGCGA
TTTTGTGCGTTAAAGAGGGCAATAAAGTACGTTTTGCTAACGAAGCGGCAGCACGTTTATTTAGACGTACCCCTGAGCAG
CTCAAACGCTCCAACGCCGAAGAACTGATTGCTCCTAAATTCTTGAATATTGAGCAAGAGCATTACTGCGGCAATATTGA
TGTTTACGTAGATGATGTGCGCCAGCACCTCTCTGCCGATGTCCTTCGCTTGCCGCAAGGTTCTGGCTTACAAGCGATGT
ACATTTTTAATGTCGGCGGCAGCGTCAATGCCGCGCGGATTCATAACCTCGAAACCGCGGTAGAAGCCCTGTCTAGCTAT
GCCTTCGAAGGCGATAAAGACAAGCTGCAAAAACTCAAGGAACTGGGTGGTGAGTTTACTCGTCTTGCAGATAAAGCCTC
GGGCGAGTATCAATCGAAACAAGATTTGATGCGTGCCGTGTTAGTCGAAGCCATGACCAGTGCCTTGAACTATTGGGAAC
GAGTCTCAGGGCAAAGCAAGTTCACGTTTGCCGAACAAAGTGGCTTGTGGCGCGTTTATCTTGACCGCAGCACCCTACAA
ACTCGTACCCTAGACAAATACTTACGAATTGAGACACTGCCTAAAACACCGCGTTGGCGAACCGTACTGAACTCGCTCGA
CTACATTCTTGAGCATTGCAAAGAAGCAGGCCCTGAACGCACTCACATCGAAATGCAGCGCGATAAATTGCAAAAACTCC
TGACCAGTGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (622-731)

• Response regulator receiver domain (Response_reg) (773-883)

• His Kinase A (phospho-acceptor) domain (HisKA) (508-573)

• PAS domain (PAS_8) (927-961)

• HAMP domain (HAMP) (423-475)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
chiS	Vibrio cholerae strain A1552	100	100	1