Detailed information    

insolico Bioinformatically predicted

Overview


Name   ssbA   Type   Machinery gene
Locus tag   EN73_RS01170 Genome accession   NZ_CP007632
Coordinates   199386..199781 (+) Length   131 a.a.
NCBI ID   WP_000282450.1    Uniprot ID   A0AAW6XW90
Organism   Streptococcus agalactiae strain NGBS572     
Function   ssDNA binding (predicted from homology)   
DNA processing

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 190488..236168 199386..199781 within 0


Gene organization within MGE regions


Location: 190488..236168
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EN73_RS01110 (EN73_01120) comYH 190777..191751 (+) 975 WP_001008570.1 class I SAM-dependent methyltransferase Machinery gene
  EN73_RS01115 (EN73_01125) - 191783..192976 (+) 1194 WP_000047535.1 acetate kinase -
  EN73_RS01120 (EN73_01130) - 193127..193333 (+) 207 WP_000798242.1 helix-turn-helix transcriptional regulator -
  EN73_RS10395 - 193392..193529 (+) 138 WP_001867090.1 hypothetical protein -
  EN73_RS01125 (EN73_01135) - 193570..194025 (+) 456 WP_000905674.1 hypothetical protein -
  EN73_RS01130 (EN73_01140) - 194094..194759 (+) 666 WP_000008111.1 CPBP family intramembrane glutamic endopeptidase -
  EN73_RS01135 (EN73_01145) proC 194780..195550 (-) 771 WP_001867096.1 pyrroline-5-carboxylate reductase -
  EN73_RS01140 (EN73_01150) pepA 195620..196687 (-) 1068 WP_001281321.1 glutamyl aminopeptidase -
  EN73_RS01145 (EN73_01155) - 196872..197111 (-) 240 WP_000660181.1 hypothetical protein -
  EN73_RS01150 (EN73_01160) - 197272..197556 (+) 285 WP_000791272.1 DUF4651 domain-containing protein -
  EN73_RS01155 (EN73_01165) - 197553..197876 (+) 324 WP_000601792.1 thioredoxin family protein -
  EN73_RS01160 (EN73_01170) ytpR 197909..198535 (+) 627 WP_000578331.1 YtpR family tRNA-binding protein -
  EN73_RS01165 (EN73_01175) - 198589..199305 (-) 717 WP_000186183.1 class I SAM-dependent methyltransferase -
  EN73_RS01170 (EN73_01180) ssbA 199386..199781 (+) 396 WP_000282450.1 single-stranded DNA-binding protein Machinery gene
  EN73_RS01175 (EN73_01185) - 199904..200548 (+) 645 WP_000416612.1 HAD family hydrolase -
  EN73_RS01180 (EN73_01190) - 200575..202320 (+) 1746 WP_000930334.1 LytS/YhcK type 5TM receptor domain-containing protein -
  EN73_RS01185 (EN73_01195) - 202301..203041 (+) 741 WP_000697630.1 LytR/AlgR family response regulator transcription factor -
  EN73_RS01190 (EN73_01200) - 203211..203666 (+) 456 WP_000683316.1 CidA/LrgA family protein -
  EN73_RS01195 (EN73_01205) lrgB 203668..204396 (+) 729 WP_000421727.1 antiholin-like protein LrgB -
  EN73_RS01200 (EN73_01210) - 204639..206267 (+) 1629 WP_000170504.1 ABC transporter substrate-binding protein -
  EN73_RS01205 (EN73_01215) - 206380..207357 (+) 978 WP_000680644.1 ABC transporter permease -
  EN73_RS01210 (EN73_01220) - 207354..208175 (+) 822 WP_000603397.1 ABC transporter permease -
  EN73_RS01215 (EN73_01225) - 208187..208990 (+) 804 WP_000140979.1 ABC transporter ATP-binding protein -
  EN73_RS01220 (EN73_01230) - 208974..209600 (+) 627 WP_000171304.1 ABC transporter ATP-binding protein -
  EN73_RS01225 (EN73_01235) treP 209882..211912 (+) 2031 WP_000434610.1 PTS system trehalose-specific EIIBC component -
  EN73_RS01230 (EN73_01240) treC 212134..213759 (+) 1626 WP_000151014.1 alpha,alpha-phosphotrehalase -
  EN73_RS01235 (EN73_01245) - 213979..216015 (+) 2037 WP_038405830.1 BglG family transcription antiterminator -
  EN73_RS01240 (EN73_01250) - 216018..216302 (+) 285 WP_000944235.1 PTS sugar transporter subunit IIB -
  EN73_RS01245 (EN73_01255) - 216315..217670 (+) 1356 WP_000677351.1 PTS ascorbate transporter subunit IIC -
  EN73_RS01250 (EN73_01260) - 217673..218530 (+) 858 WP_000203492.1 transketolase -
  EN73_RS01255 (EN73_01265) - 218527..219456 (+) 930 WP_001203828.1 transketolase family protein -
  EN73_RS01260 (EN73_01270) - 219565..220824 (+) 1260 WP_001203074.1 ferric reductase-like transmembrane domain-containing protein -
  EN73_RS01265 (EN73_01275) rpsO 220912..221181 (+) 270 WP_001018249.1 30S ribosomal protein S15 -
  EN73_RS01270 (EN73_01280) pnp 221562..223691 (+) 2130 WP_000043857.1 polyribonucleotide nucleotidyltransferase -
  EN73_RS01275 (EN73_01285) - 223693..224445 (+) 753 WP_000204780.1 SseB family protein -
  EN73_RS01280 (EN73_01290) cysE 224454..225038 (+) 585 WP_000539954.1 serine O-acetyltransferase -
  EN73_RS01285 (EN73_01295) - 225048..225230 (+) 183 WP_000656477.1 hypothetical protein -
  EN73_RS01290 (EN73_01300) cysS 225227..226570 (+) 1344 WP_000591129.1 cysteine--tRNA ligase -
  EN73_RS01295 (EN73_01305) - 226563..226949 (+) 387 WP_000568029.1 Mini-ribonuclease 3 -
  EN73_RS01300 (EN73_01310) rlmB 227052..227807 (+) 756 WP_000178023.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  EN73_RS01305 (EN73_01315) - 227804..228322 (+) 519 WP_000716636.1 NYN domain-containing protein -
  EN73_RS01310 (EN73_01320) - 228415..229275 (+) 861 WP_000143135.1 DegV family protein -
  EN73_RS01315 (EN73_01335) - 229813..229932 (+) 120 Protein_208 helix-turn-helix transcriptional regulator -
  EN73_RS01320 (EN73_01340) - 230250..231416 (-) 1167 WP_000160598.1 IS30-like element ISSag9 family transposase -
  EN73_RS01325 (EN73_01345) rplM 231717..232163 (+) 447 WP_001867156.1 50S ribosomal protein L13 -
  EN73_RS01330 (EN73_01350) rpsI 232184..232576 (+) 393 WP_000035940.1 30S ribosomal protein S9 -
  EN73_RS01335 (EN73_01355) - 232722..233876 (-) 1155 WP_000110711.1 site-specific integrase -
  EN73_RS01340 (EN73_01360) - 233931..234449 (-) 519 WP_000181342.1 helix-turn-helix domain-containing protein -
  EN73_RS01345 (EN73_01365) - 234596..234880 (+) 285 WP_001287945.1 hypothetical protein -
  EN73_RS01350 (EN73_01370) - 234892..235746 (+) 855 WP_000005759.1 phage replisome organizer N-terminal domain-containing protein -
  EN73_RS01355 (EN73_01375) - 235757..236047 (+) 291 WP_000158581.1 DUF5962 family protein -

Sequence


Protein


Download         Length: 131 a.a.        Molecular weight: 14790.80 Da        Isoelectric Point: 7.0189

>NTDB_id=121877 EN73_RS01170 WP_000282450.1 199386..199781(+) (ssbA) [Streptococcus agalactiae strain NGBS572]
MYNKVIMIGRLTAKPEMVKTPTDKSVTRATVAVNRRFKGSNGEREADFINVVMWGRLAETLASYGTKGSLISVDGELRTR
KYEKDGQTHYITEVLASSFQLLESRSQRAMRENNISGDLSDLVLEEEELPF

Nucleotide


Download         Length: 396 bp        

>NTDB_id=121877 EN73_RS01170 WP_000282450.1 199386..199781(+) (ssbA) [Streptococcus agalactiae strain NGBS572]
ATGTATAATAAAGTTATTATGATTGGGCGTCTAACAGCAAAGCCTGAGATGGTAAAAACACCAACTGACAAGTCAGTAAC
GCGTGCAACTGTTGCTGTTAATAGACGCTTTAAAGGAAGTAATGGTGAGCGTGAAGCAGATTTTATTAATGTGGTTATGT
GGGGTCGTCTAGCGGAAACCCTTGCGAGCTATGGGACAAAGGGCTCTTTAATTTCAGTAGATGGTGAATTGCGTACGCGC
AAGTACGAAAAGGATGGTCAAACGCACTATATCACTGAAGTATTAGCATCATCATTTCAGTTGCTAGAAAGCCGTTCCCA
ACGTGCTATGCGTGAAAATAACATTTCTGGTGATTTGTCAGATTTAGTATTGGAAGAAGAGGAGCTCCCCTTTTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ssbA Streptococcus mutans UA159

80.153

100

0.802

  ssbB/cilA Streptococcus pneumoniae R6

77.863

100

0.779

  ssbB/cilA Streptococcus pneumoniae Rx1

77.863

100

0.779

  ssbB/cilA Streptococcus pneumoniae D39

77.863

100

0.779

  ssbB/cilA Streptococcus pneumoniae TIGR4

77.099

100

0.771

  ssbB Streptococcus sobrinus strain NIDR 6715-7

76.336

100

0.763

  ssbB/cilA Streptococcus mitis NCTC 12261

76.336

100

0.763

  ssbB/cilA Streptococcus mitis SK321

76.336

100

0.763

  ssbB Lactococcus lactis subsp. cremoris KW2

59.649

87.023

0.519

  ssbA Bacillus subtilis subsp. subtilis str. 168

51.402

81.679

0.42

  ssb Latilactobacillus sakei subsp. sakei 23K

46.903

86.26

0.405


Multiple sequence alignment