Detailed information
Bioinformatically predicted
Overview
| Name | comYH | Type | Machinery gene |
| Locus tag | EN73_RS01110 | Genome accession | NZ_CP007632 |
| Coordinates | 190777..191751 (+) | Length | 324 a.a. |
| NCBI ID | WP_001008570.1 | Uniprot ID | A0AAW6XQQ3 |
| Organism | Streptococcus agalactiae strain NGBS572 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 190488..236168 | 190777..191751 | within | 0 |
Gene organization within MGE regions
Location: 190488..236168
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EN73_RS01110 (EN73_01120) | comYH | 190777..191751 (+) | 975 | WP_001008570.1 | class I SAM-dependent methyltransferase | Machinery gene |
| EN73_RS01115 (EN73_01125) | - | 191783..192976 (+) | 1194 | WP_000047535.1 | acetate kinase | - |
| EN73_RS01120 (EN73_01130) | - | 193127..193333 (+) | 207 | WP_000798242.1 | helix-turn-helix transcriptional regulator | - |
| EN73_RS10395 | - | 193392..193529 (+) | 138 | WP_001867090.1 | hypothetical protein | - |
| EN73_RS01125 (EN73_01135) | - | 193570..194025 (+) | 456 | WP_000905674.1 | hypothetical protein | - |
| EN73_RS01130 (EN73_01140) | - | 194094..194759 (+) | 666 | WP_000008111.1 | CPBP family intramembrane glutamic endopeptidase | - |
| EN73_RS01135 (EN73_01145) | proC | 194780..195550 (-) | 771 | WP_001867096.1 | pyrroline-5-carboxylate reductase | - |
| EN73_RS01140 (EN73_01150) | pepA | 195620..196687 (-) | 1068 | WP_001281321.1 | glutamyl aminopeptidase | - |
| EN73_RS01145 (EN73_01155) | - | 196872..197111 (-) | 240 | WP_000660181.1 | hypothetical protein | - |
| EN73_RS01150 (EN73_01160) | - | 197272..197556 (+) | 285 | WP_000791272.1 | DUF4651 domain-containing protein | - |
| EN73_RS01155 (EN73_01165) | - | 197553..197876 (+) | 324 | WP_000601792.1 | thioredoxin family protein | - |
| EN73_RS01160 (EN73_01170) | ytpR | 197909..198535 (+) | 627 | WP_000578331.1 | YtpR family tRNA-binding protein | - |
| EN73_RS01165 (EN73_01175) | - | 198589..199305 (-) | 717 | WP_000186183.1 | class I SAM-dependent methyltransferase | - |
| EN73_RS01170 (EN73_01180) | ssbA | 199386..199781 (+) | 396 | WP_000282450.1 | single-stranded DNA-binding protein | Machinery gene |
| EN73_RS01175 (EN73_01185) | - | 199904..200548 (+) | 645 | WP_000416612.1 | HAD family hydrolase | - |
| EN73_RS01180 (EN73_01190) | - | 200575..202320 (+) | 1746 | WP_000930334.1 | LytS/YhcK type 5TM receptor domain-containing protein | - |
| EN73_RS01185 (EN73_01195) | - | 202301..203041 (+) | 741 | WP_000697630.1 | LytR/AlgR family response regulator transcription factor | - |
| EN73_RS01190 (EN73_01200) | - | 203211..203666 (+) | 456 | WP_000683316.1 | CidA/LrgA family protein | - |
| EN73_RS01195 (EN73_01205) | lrgB | 203668..204396 (+) | 729 | WP_000421727.1 | antiholin-like protein LrgB | - |
| EN73_RS01200 (EN73_01210) | - | 204639..206267 (+) | 1629 | WP_000170504.1 | ABC transporter substrate-binding protein | - |
| EN73_RS01205 (EN73_01215) | - | 206380..207357 (+) | 978 | WP_000680644.1 | ABC transporter permease | - |
| EN73_RS01210 (EN73_01220) | - | 207354..208175 (+) | 822 | WP_000603397.1 | ABC transporter permease | - |
| EN73_RS01215 (EN73_01225) | - | 208187..208990 (+) | 804 | WP_000140979.1 | ABC transporter ATP-binding protein | - |
| EN73_RS01220 (EN73_01230) | - | 208974..209600 (+) | 627 | WP_000171304.1 | ABC transporter ATP-binding protein | - |
| EN73_RS01225 (EN73_01235) | treP | 209882..211912 (+) | 2031 | WP_000434610.1 | PTS system trehalose-specific EIIBC component | - |
| EN73_RS01230 (EN73_01240) | treC | 212134..213759 (+) | 1626 | WP_000151014.1 | alpha,alpha-phosphotrehalase | - |
| EN73_RS01235 (EN73_01245) | - | 213979..216015 (+) | 2037 | WP_038405830.1 | BglG family transcription antiterminator | - |
| EN73_RS01240 (EN73_01250) | - | 216018..216302 (+) | 285 | WP_000944235.1 | PTS sugar transporter subunit IIB | - |
| EN73_RS01245 (EN73_01255) | - | 216315..217670 (+) | 1356 | WP_000677351.1 | PTS ascorbate transporter subunit IIC | - |
| EN73_RS01250 (EN73_01260) | - | 217673..218530 (+) | 858 | WP_000203492.1 | transketolase | - |
| EN73_RS01255 (EN73_01265) | - | 218527..219456 (+) | 930 | WP_001203828.1 | transketolase family protein | - |
| EN73_RS01260 (EN73_01270) | - | 219565..220824 (+) | 1260 | WP_001203074.1 | ferric reductase-like transmembrane domain-containing protein | - |
| EN73_RS01265 (EN73_01275) | rpsO | 220912..221181 (+) | 270 | WP_001018249.1 | 30S ribosomal protein S15 | - |
| EN73_RS01270 (EN73_01280) | pnp | 221562..223691 (+) | 2130 | WP_000043857.1 | polyribonucleotide nucleotidyltransferase | - |
| EN73_RS01275 (EN73_01285) | - | 223693..224445 (+) | 753 | WP_000204780.1 | SseB family protein | - |
| EN73_RS01280 (EN73_01290) | cysE | 224454..225038 (+) | 585 | WP_000539954.1 | serine O-acetyltransferase | - |
| EN73_RS01285 (EN73_01295) | - | 225048..225230 (+) | 183 | WP_000656477.1 | hypothetical protein | - |
| EN73_RS01290 (EN73_01300) | cysS | 225227..226570 (+) | 1344 | WP_000591129.1 | cysteine--tRNA ligase | - |
| EN73_RS01295 (EN73_01305) | - | 226563..226949 (+) | 387 | WP_000568029.1 | Mini-ribonuclease 3 | - |
| EN73_RS01300 (EN73_01310) | rlmB | 227052..227807 (+) | 756 | WP_000178023.1 | 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB | - |
| EN73_RS01305 (EN73_01315) | - | 227804..228322 (+) | 519 | WP_000716636.1 | NYN domain-containing protein | - |
| EN73_RS01310 (EN73_01320) | - | 228415..229275 (+) | 861 | WP_000143135.1 | DegV family protein | - |
| EN73_RS01315 (EN73_01335) | - | 229813..229932 (+) | 120 | Protein_208 | helix-turn-helix transcriptional regulator | - |
| EN73_RS01320 (EN73_01340) | - | 230250..231416 (-) | 1167 | WP_000160598.1 | IS30-like element ISSag9 family transposase | - |
| EN73_RS01325 (EN73_01345) | rplM | 231717..232163 (+) | 447 | WP_001867156.1 | 50S ribosomal protein L13 | - |
| EN73_RS01330 (EN73_01350) | rpsI | 232184..232576 (+) | 393 | WP_000035940.1 | 30S ribosomal protein S9 | - |
| EN73_RS01335 (EN73_01355) | - | 232722..233876 (-) | 1155 | WP_000110711.1 | site-specific integrase | - |
| EN73_RS01340 (EN73_01360) | - | 233931..234449 (-) | 519 | WP_000181342.1 | helix-turn-helix domain-containing protein | - |
| EN73_RS01345 (EN73_01365) | - | 234596..234880 (+) | 285 | WP_001287945.1 | hypothetical protein | - |
| EN73_RS01350 (EN73_01370) | - | 234892..235746 (+) | 855 | WP_000005759.1 | phage replisome organizer N-terminal domain-containing protein | - |
| EN73_RS01355 (EN73_01375) | - | 235757..236047 (+) | 291 | WP_000158581.1 | DUF5962 family protein | - |
Sequence
Protein
Download Length: 324 a.a. Molecular weight: 37100.99 Da Isoelectric Point: 4.4041
>NTDB_id=121875 EN73_RS01110 WP_001008570.1 190777..191751(+) (comYH) [Streptococcus agalactiae strain NGBS572]
MNFEKIETAYELILENIQTIENQLKTHIYDALIEQNSYYLGSSCDLDIVVVNNQKLRQLDLSQEEWRRTFQFIFIKSAQT
EQLQANHQFTPDSIGFILLFLLEELTSQETVDVLEIGSGTGNLAQTLLNNSSKELNYMGIEVDDLLIDLSASIAEIIGSS
AQFIQEDAVRPQILKESDVIISDLPIGYYPNDDIAKRYAVSSSKEHTYAHHLLMEQSLKYLKKDGIAIFLAPENLLTSPQ
SDLLKEWLKGYADVIAVLTLPETIFGSRQNAKSIFVLKKQAEQKPETFVYPLTDLQNRENMANFIENFQKWSRENSHYSK
NMIE
MNFEKIETAYELILENIQTIENQLKTHIYDALIEQNSYYLGSSCDLDIVVVNNQKLRQLDLSQEEWRRTFQFIFIKSAQT
EQLQANHQFTPDSIGFILLFLLEELTSQETVDVLEIGSGTGNLAQTLLNNSSKELNYMGIEVDDLLIDLSASIAEIIGSS
AQFIQEDAVRPQILKESDVIISDLPIGYYPNDDIAKRYAVSSSKEHTYAHHLLMEQSLKYLKKDGIAIFLAPENLLTSPQ
SDLLKEWLKGYADVIAVLTLPETIFGSRQNAKSIFVLKKQAEQKPETFVYPLTDLQNRENMANFIENFQKWSRENSHYSK
NMIE
Nucleotide
Download Length: 975 bp
>NTDB_id=121875 EN73_RS01110 WP_001008570.1 190777..191751(+) (comYH) [Streptococcus agalactiae strain NGBS572]
ATGAATTTTGAAAAAATTGAGACAGCCTATGAGCTGATTTTAGAAAATATCCAAACGATTGAGAACCAATTAAAAACTCA
TATTTATGATGCCTTAATTGAACAGAACTCTTATTACCTTGGTTCAAGTTGTGATTTAGATATTGTTGTGGTGAATAACC
AAAAATTACGTCAACTTGACTTAAGTCAAGAAGAATGGCGTCGCACTTTCCAGTTCATTTTTATCAAATCTGCGCAAACA
GAGCAATTACAAGCTAATCATCAGTTTACGCCAGATAGTATTGGTTTTATCTTGTTATTTCTTTTGGAAGAATTAACGAG
TCAAGAGACAGTGGATGTCTTGGAAATTGGAAGTGGAACTGGGAATTTAGCTCAGACTCTCCTCAATAACAGCTCGAAAG
AGTTAAATTATATGGGCATTGAAGTTGATGATCTTTTGATTGATCTATCAGCAAGCATTGCTGAAATTATAGGTTCTAGT
GCCCAATTTATCCAAGAGGATGCCGTTAGACCACAAATTTTGAAAGAAAGCGATGTAATCATTAGTGATTTACCAATTGG
CTATTATCCTAATGATGATATTGCTAAACGATATGCTGTATCAAGTTCTAAAGAGCACACCTATGCTCACCATCTATTGA
TGGAGCAATCTCTTAAATATTTGAAAAAAGATGGAATCGCTATATTTTTAGCACCCGAAAACCTTTTAACAAGTCCACAA
AGTGATTTGCTGAAGGAGTGGTTAAAAGGATATGCAGATGTCATTGCCGTTTTAACTCTACCAGAAACTATTTTTGGAAG
TCGTCAAAATGCGAAATCTATATTTGTTCTCAAGAAGCAAGCAGAACAAAAACCAGAAACCTTTGTATATCCGCTGACAG
ATTTGCAAAATCGTGAGAATATGGCAAACTTCATTGAAAATTTTCAAAAATGGAGCAGAGAAAATAGTCATTACTCAAAA
AATATGATAGAATAG
ATGAATTTTGAAAAAATTGAGACAGCCTATGAGCTGATTTTAGAAAATATCCAAACGATTGAGAACCAATTAAAAACTCA
TATTTATGATGCCTTAATTGAACAGAACTCTTATTACCTTGGTTCAAGTTGTGATTTAGATATTGTTGTGGTGAATAACC
AAAAATTACGTCAACTTGACTTAAGTCAAGAAGAATGGCGTCGCACTTTCCAGTTCATTTTTATCAAATCTGCGCAAACA
GAGCAATTACAAGCTAATCATCAGTTTACGCCAGATAGTATTGGTTTTATCTTGTTATTTCTTTTGGAAGAATTAACGAG
TCAAGAGACAGTGGATGTCTTGGAAATTGGAAGTGGAACTGGGAATTTAGCTCAGACTCTCCTCAATAACAGCTCGAAAG
AGTTAAATTATATGGGCATTGAAGTTGATGATCTTTTGATTGATCTATCAGCAAGCATTGCTGAAATTATAGGTTCTAGT
GCCCAATTTATCCAAGAGGATGCCGTTAGACCACAAATTTTGAAAGAAAGCGATGTAATCATTAGTGATTTACCAATTGG
CTATTATCCTAATGATGATATTGCTAAACGATATGCTGTATCAAGTTCTAAAGAGCACACCTATGCTCACCATCTATTGA
TGGAGCAATCTCTTAAATATTTGAAAAAAGATGGAATCGCTATATTTTTAGCACCCGAAAACCTTTTAACAAGTCCACAA
AGTGATTTGCTGAAGGAGTGGTTAAAAGGATATGCAGATGTCATTGCCGTTTTAACTCTACCAGAAACTATTTTTGGAAG
TCGTCAAAATGCGAAATCTATATTTGTTCTCAAGAAGCAAGCAGAACAAAAACCAGAAACCTTTGTATATCCGCTGACAG
ATTTGCAAAATCGTGAGAATATGGCAAACTTCATTGAAAATTTTCAAAAATGGAGCAGAGAAAATAGTCATTACTCAAAA
AATATGATAGAATAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comYH | Streptococcus mutans UA159 |
66.984 |
97.222 |
0.651 |
| comYH | Streptococcus mutans UA140 |
66.984 |
97.222 |
0.651 |