Detailed information NTG0121856

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: EN71_RS09665
• Genome accession: NZ_CP007631
• Coordinates: 1914817..1917264 (-)
• Length: 815 a.a.
• NCBI ID: WP_000020283.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain NGBS061
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1909817..1922264

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EN71_RS09640 (EN72_09860)	-	1910098..1911354 (+)	1257	WP_001285395.1	toxic anion resistance protein	-
EN71_RS09645 (EN72_09865)	hslO	1911494..1912369 (+)	876	WP_000357828.1	Hsp33 family molecular chaperone HslO	-
EN71_RS09650 (EN72_09870)	dusB	1912353..1913330 (+)	978	WP_000192732.1	tRNA dihydrouridine synthase DusB	-
EN71_RS09655 (EN72_09875)	-	1913451..1914092 (+)	642	WP_000909523.1	deoxynucleoside kinase	-
EN71_RS09660 (EN72_09880)	-	1914106..1914597 (+)	492	WP_000586898.1	GNAT family N-acetyltransferase	-
EN71_RS09665 (EN72_09885)	clpC	1914817..1917264 (-)	2448	WP_000020283.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
EN71_RS09670 (EN72_09890)	-	1917261..1917725 (-)	465	WP_000985641.1	CtsR family transcriptional regulator	-
EN71_RS09675 (EN72_09895)	-	1917898..1918359 (+)	462	WP_001106578.1	COG2426 family protein	-
EN71_RS09680 (EN72_09900)	tsf	1918519..1919559 (-)	1041	WP_000808080.1	translation elongation factor Ts	-
EN71_RS09685 (EN72_09905)	rpsB	1919653..1920423 (-)	771	WP_000268453.1	30S ribosomal protein S2	-
EN71_RS09690 (EN72_09910)	ahpC	1920700..1921260 (+)	561	WP_000060538.1	alkyl hydroperoxide reductase subunit C	-

Sequence

Protein

• Length: 815 a.a.
• Molecular weight: 90596.06 Da
• Isoelectric Point: 5.8782

>NTDB_id=121856 EN71_RS09665 WP_000020283.1 1914817..1917264(-) (clpC) [Streptococcus agalactiae strain NGBS061]
MSHYSIKLQEVFRLAQFQAARYESHYLESWHLLLAMVLVHDSVAGLTFAEYESEVAIEEYEAATILALGRAPKEEITDYQ
FLEQSSALKKILKLAENISIVVGAEDVGTEHVLLAMLVNKDLLATRILELVGFRGQDDGESVRMVDLRKALERHAGFTKD
DIKAIYELRNPKKAKSGASFSDMMKPPSTAGDLADFTRDLSQMAVDGEIEPVIGRDTEISRMVQVLSRKTKNNPVLVGDA
GVGKTALAYGLAQRIANGNIPYELRDMRVLELDMMSVVAGTRFRGDFEERMNQIIADIEEDGHIILFIDELHTIMGSGSG
IDSTLDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVLVEEPNLEDAYEILLGLKPAYEAFHNVTISDE
AVMTAVKVAHRYLTSKNLPDSAIDLLDEASATVQMMIKKNAPSLLTEVDQAILDDDMKSASKALKASHKDKKRKPIAVTE
DHIMATLSRLSGIPVEKLTQADSKKYLNLEKELHKRVIGQDDAVTAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTE
LAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQV
LDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDISHDYTAMQKRIMEELKKAYRPEFINRIDEKVVFHS
LSQDNMREVVKIMVKPLILALKDKGMDLKFQPSALKHLAEDGYDIEMGARPLRRTIQTQVEDHLSELLLANQVKEGQVIK
IGVSKGKLKFDIAKS

Nucleotide

• Length: 2448 bp

>NTDB_id=121856 EN71_RS09665 WP_000020283.1 1914817..1917264(-) (clpC) [Streptococcus agalactiae strain NGBS061]
ATGAGTCATTATTCCATAAAATTACAAGAAGTATTCAGATTGGCGCAATTTCAAGCAGCACGCTATGAAAGTCACTATTT
AGAAAGCTGGCATCTTCTTTTAGCAATGGTTTTAGTTCATGATTCAGTAGCTGGTTTGACATTTGCTGAATATGAGTCTG
AAGTTGCAATTGAAGAGTACGAAGCAGCAACAATTTTAGCTTTAGGTAGAGCACCGAAAGAAGAGATTACCGATTATCAA
TTTTTAGAGCAATCATCGGCTTTGAAAAAGATCTTAAAGTTAGCAGAAAATATTAGTATCGTAGTAGGAGCTGAAGATGT
GGGTACTGAACATGTCTTGCTTGCTATGTTGGTTAATAAAGATTTATTAGCCACACGTATCTTAGAATTAGTTGGTTTTA
GAGGTCAAGACGATGGTGAATCAGTTCGTATGGTTGATTTACGTAAGGCTCTAGAACGTCATGCCGGTTTTACAAAAGAT
GATATCAAAGCAATTTATGAATTACGTAATCCTAAAAAAGCAAAGTCGGGTGCTTCTTTTTCTGATATGATGAAACCACC
GAGTACTGCTGGTGATTTAGCTGATTTCACACGTGATTTATCACAGATGGCGGTTGATGGGGAAATTGAACCTGTTATTG
GGCGTGATACAGAAATTTCACGTATGGTCCAAGTCTTAAGTCGTAAAACAAAGAATAATCCTGTCTTAGTTGGAGATGCG
GGTGTCGGTAAAACAGCTTTGGCGTACGGTCTAGCACAACGTATTGCTAATGGAAATATTCCTTATGAGCTTAGAGATAT
GCGTGTTCTAGAGTTAGATATGATGAGCGTTGTTGCTGGAACTCGTTTTCGTGGTGATTTTGAGGAACGTATGAATCAAA
TCATTGCAGATATTGAAGAAGACGGTCATATTATTCTTTTCATTGATGAACTGCATACTATTATGGGTTCTGGCTCTGGT
ATTGATAGCACACTTGATGCTGCTAATATTTTAAAACCAGCTTTGGCCCGAGGCACTTTACGCACTGTTGGAGCAACAAC
TCAAGAGGAATATCAAAAGCATATTGAAAAAGATGCTGCTTTATCTCGTCGCTTTGCAAAAGTTTTAGTAGAAGAACCAA
ATCTTGAAGACGCTTATGAAATTCTACTTGGATTGAAGCCAGCGTATGAAGCCTTTCATAATGTTACTATTTCAGATGAA
GCAGTTATGACTGCTGTAAAAGTGGCTCATCGTTATTTGACAAGTAAGAATTTACCAGACTCAGCTATAGACTTACTTGA
TGAAGCTTCTGCCACTGTGCAAATGATGATTAAGAAAAATGCTCCTTCGCTTTTAACAGAAGTTGACCAAGCTATTTTAG
ATGATGATATGAAATCTGCTTCTAAAGCTCTAAAAGCAAGCCATAAGGATAAAAAGCGTAAGCCTATTGCCGTAACCGAA
GATCATATTATGGCAACTCTCAGCCGTCTATCTGGTATTCCTGTTGAAAAATTGACACAAGCTGATAGTAAAAAATACCT
CAATTTAGAAAAAGAATTGCATAAACGTGTTATCGGTCAAGATGATGCAGTTACCGCCATTAGTCGTGCTATCCGTCGCA
ATCAATCTGGCATTCGTACTGGTAAGCGTCCTATTGGTTCCTTTATGTTCTTGGGACCAACTGGTGTTGGTAAGACAGAG
TTAGCAAAAGCCTTGGCAGAAGTGTTGTTTGATGATGAATCAGCCCTAATTCGTTTTGATATGTCGGAATATATGGAAAA
ATTCGCAGCTTCTCGCCTGAATGGGGCACCTCCAGGTTATGTTGGTTATGATGAAGGAGGAGAGCTGACTGAAAAAGTAC
GCAATAAACCATATTCAGTTTTACTTTTTGATGAAGTTGAAAAAGCTCATCCAGATATTTTTAATGTATTATTACAAGTG
CTTGATGATGGCGTTTTAACAGATAGTCGAGGACGAAAAGTTGATTTTTCAAATACTATAATCATTATGACTTCTAATTT
AGGAGCAACTGCATTACGTGACGATAAAACAGTTGGTTTTGGAGCTAAGGATATCAGCCATGATTATACTGCTATGCAAA
AACGTATTATGGAGGAGCTTAAAAAAGCTTATCGACCAGAATTTATCAATCGTATTGATGAGAAAGTTGTATTCCATAGT
CTCAGTCAAGATAATATGCGTGAAGTTGTGAAAATTATGGTTAAACCTTTAATTTTAGCGCTTAAAGATAAAGGTATGGA
TCTGAAATTCCAGCCTTCAGCCTTGAAACACTTGGCAGAGGATGGCTATGATATAGAAATGGGTGCTCGTCCACTGCGTA
GAACTATTCAAACGCAAGTAGAGGATCATTTATCAGAACTACTATTGGCAAATCAAGTGAAAGAGGGGCAAGTAATTAAG
ATTGGCGTATCCAAAGGCAAATTGAAATTTGATATTGCAAAATCATAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (721-801)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (105-132)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-46)

• ATPase family associated with various cellular activities (AAA) (AAA) (235-367)

• AAA lid domain (AAA_lid_9) (375-471)

• AAA domain (Cdc48 subfamily) (AAA_2) (543-714)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	76.601	99.632	0.763
clpC	Streptococcus thermophilus LMG 18311	72.705	100	0.729
clpC	Streptococcus thermophilus LMD-9	72.583	100	0.728
clpC	Streptococcus pneumoniae Rx1	68.55	99.877	0.685
clpC	Streptococcus pneumoniae D39	68.55	99.877	0.685
clpC	Streptococcus pneumoniae TIGR4	68.55	99.877	0.685
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.558	100	0.496
clpC	Bacillus subtilis subsp. subtilis str. 168	45.324	100	0.464
clpE	Streptococcus mutans UA159	46.395	78.282	0.363