Detailed information NTG0121829

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: EN71_RS02640
• Genome accession: NZ_CP007631
• Coordinates: 464935..466008 (+)
• Length: 357 a.a.
• NCBI ID: WP_000796095.1
• Uniprot ID: A0A0E1EG10
• Organism: Streptococcus agalactiae strain NGBS061
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 459935..471008

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EN71_RS02610 (EN72_02635)	-	460828..461892 (+)	1065	WP_000021309.1	MmcQ/YjbR family DNA-binding protein	-
EN71_RS02615 (EN72_02640)	asnA	462006..462998 (+)	993	WP_000748017.1	aspartate--ammonia ligase	-
EN71_RS02620 (EN72_02645)	-	463043..463492 (-)	450	WP_000592263.1	thiol reductase thioredoxin	-
EN71_RS02625 (EN72_02650)	rsmD	463622..464161 (+)	540	WP_001266830.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
EN71_RS02630 (EN72_02655)	-	464173..464463 (+)	291	WP_000384889.1	hypothetical protein	-
EN71_RS02635 (EN72_02660)	coaD	464460..464945 (+)	486	WP_000161892.1	pantetheine-phosphate adenylyltransferase	-
EN71_RS02640 (EN72_02665)	sepM	464935..466008 (+)	1074	WP_000796095.1	SepM family pheromone-processing serine protease	Regulator
EN71_RS02645 (EN72_02670)	-	466083..467415 (+)	1333	Protein_442	bifunctional metallophosphatase/5'-nucleotidase	-
EN71_RS02650 (EN72_02675)	-	467484..468062 (+)	579	WP_001224500.1	YutD family protein	-
EN71_RS02655 (EN72_02680)	rlmN	468113..469219 (+)	1107	WP_001124990.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
EN71_RS02660 (EN72_02685)	-	469219..469734 (+)	516	WP_000919802.1	VanZ family protein	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 39199.43 Da
• Isoelectric Point: 10.4385

>NTDB_id=121829 EN71_RS02640 WP_000796095.1 464935..466008(+) (sepM) [Streptococcus agalactiae strain NGBS061]
MKNRDPKRKHKSLLGLLKWWIIGFAFLLLVLASLVVRLPYYLEMPGGAYDIRSVLKVNKKADKAKGSYNFVAVSVSQATP
AQVLYAWLTPFTELSSKEETTGGFSNDDYLRINQFYMETSQNESIYQALKLANKQVSLTYKGVYVLNLAKNSTFKDRLHL
ADTVTGVNGKSFKNSSQLIKYVAALHLGDKVKVQYTSQGKKKESVGKVIKLSNGKNGIGIGLTDHTEVLSDVPVDFNTEG
VGGPSAGLMFTLAIYDQLVKEDLRKGRKIAGTGTIEQNGHVGDIGGAGLKVVSAAKKGMDIFFVPNNPIDKNAKKGKTKV
QTNYQEAKAAAKRLGTKMKIVPVQNVQQAIDYLKKTK

Nucleotide

• Length: 1074 bp

>NTDB_id=121829 EN71_RS02640 WP_000796095.1 464935..466008(+) (sepM) [Streptococcus agalactiae strain NGBS061]
GTGAAGAATAGAGATCCAAAAAGAAAACATAAAAGTTTACTAGGTCTGCTTAAATGGTGGATTATAGGTTTTGCTTTTTT
ATTGTTAGTATTAGCAAGCCTTGTAGTGAGACTACCTTATTATTTGGAAATGCCAGGTGGAGCTTATGATATCCGTTCGG
TATTGAAAGTGAATAAAAAGGCTGATAAAGCTAAGGGTTCGTACAATTTTGTAGCGGTATCTGTCAGTCAAGCAACGCCA
GCTCAGGTTCTTTATGCTTGGTTAACTCCTTTTACAGAATTATCTAGTAAAGAGGAGACAACAGGTGGCTTTAGTAATGA
CGATTATCTCAGAATTAATCAATTCTACATGGAGACTTCTCAAAATGAGTCCATCTATCAAGCTTTAAAGTTAGCTAATA
AGCAAGTATCTCTTACTTATAAAGGAGTTTATGTGCTTAACTTAGCTAAAAATTCGACATTTAAAGATAGATTACATTTA
GCTGATACAGTCACAGGAGTTAATGGCAAAAGTTTCAAAAATTCTTCTCAACTTATCAAATATGTTGCAGCTCTTCATCT
AGGTGATAAAGTAAAGGTACAATACACAAGTCAAGGTAAAAAGAAAGAATCAGTTGGTAAAGTTATTAAACTATCAAACG
GTAAAAATGGTATTGGTATCGGTTTGACAGACCATACAGAAGTATTATCTGATGTTCCTGTGGACTTTAATACTGAAGGT
GTTGGAGGACCAAGTGCAGGTTTAATGTTTACTTTAGCGATTTACGACCAATTGGTTAAAGAAGATTTACGTAAAGGACG
TAAGATTGCAGGTACTGGTACTATTGAGCAAAATGGGCATGTTGGCGATATTGGTGGAGCAGGTTTGAAAGTTGTTTCAG
CGGCTAAAAAAGGAATGGATATTTTCTTTGTTCCTAATAATCCGATCGATAAAAATGCTAAAAAAGGCAAAACAAAGGTT
CAGACGAATTATCAAGAGGCAAAAGCAGCAGCTAAGCGATTAGGTACGAAGATGAAAATTGTACCAGTTCAAAATGTTCA
GCAAGCTATTGATTATTTGAAAAAAACAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (137-203)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (242-307)

3D structure

• AlphaFold DB: A0A0E1EG10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.322	94.958	0.658