Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   EG63_RS03780 Genome accession   NZ_CP007604
Coordinates   788269..790053 (+) Length   594 a.a.
NCBI ID   WP_038417709.1    Uniprot ID   -
Organism   Helicobacter pylori strain BM013A     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 783269..795053
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EG63_RS03750 (EG63_03905) motB 784033..784806 (+) 774 WP_038417705.1 flagellar motor protein MotB -
  EG63_RS03755 (EG63_03910) - 784812..785249 (+) 438 WP_025444993.1 hypothetical protein -
  EG63_RS03760 (EG63_03915) - 785318..786979 (+) 1662 WP_038417706.1 glycine betaine ABC transporter substrate-binding protein -
  EG63_RS03765 (EG63_03920) - 786983..787624 (+) 642 WP_038417707.1 ATP-binding cassette domain-containing protein -
  EG63_RS03770 (EG63_03925) - 787636..787815 (-) 180 WP_001847249.1 hypothetical protein -
  EG63_RS03775 (EG63_03930) - 787807..788268 (+) 462 WP_000437165.1 hypothetical protein -
  EG63_RS03780 (EG63_03935) uvrC 788269..790053 (+) 1785 WP_038417709.1 excinuclease ABC subunit UvrC Machinery gene
  EG63_RS03785 (EG63_03940) - 790064..791329 (+) 1266 WP_038417711.1 homoserine dehydrogenase -
  EG63_RS03790 (EG63_03945) - 791330..791674 (+) 345 WP_038417712.1 YraN family protein -
  EG63_RS03795 (EG63_03950) trxA 791763..792083 (+) 321 WP_000020204.1 thioredoxin -
  EG63_RS03800 (EG63_03955) trxB 792089..793024 (+) 936 WP_000564430.1 thioredoxin-disulfide reductase -
  EG63_RS03805 (EG63_03965) - 793379..794200 (+) 822 WP_038417714.1 glycosyltransferase family 25 protein -
  EG63_RS03810 (EG63_03970) - 794431..794679 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68550.75 Da        Isoelectric Point: 9.6283

>NTDB_id=121572 EG63_RS03780 WP_038417709.1 788269..790053(+) (uvrC) [Helicobacter pylori strain BM013A]
MADLLSSLKNLSNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVRNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDRLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGGINKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLS
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKASNEDLILEEARSLFELECVPYRVEIFDT
SHHANSQCVGGMVVYENNAFQKDSYRRYHLKGSDEYAQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIAVEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASDQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=121572 EG63_RS03780 WP_038417709.1 788269..790053(+) (uvrC) [Helicobacter pylori strain BM013A]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTAACAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
GCTCTATATCGGTAAAGCAAAAAACTTAAAAAAACGCATCAAAAGCTATTTTTCTGTCCGTAACAATGAAATCACGCCCA
ACCATCGCGCAAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCCTATATTTATATGGATTTTTCCACCGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTGGACAGCTTGTATGAATTGCTCCCATTGGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAACAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAGGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGCGGGATCAATAAAGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAGATCTTATTGAGC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCCCATCAATACTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAAATTTTTAGCCAAGAAAAAGCCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTGAATTAGAGTGCGTGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACAACGCCTTCCAAAAAGACTCTTATCGGCG
CTACCATTTAAAAGGCTCTGATGAATACGCTCAAATGAGCGAGTTGCTCACTAGAAGAGCTTTAGACTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTGATTGATGGAGGGAGGGCGCAATTAAACATCGCTGTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAGGCTTATCGCTCTAAAGGGGGTGCTAAAGACATTAT
CCATACGCCTAGCAATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGATCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.306

100

0.973

Multiple sequence alignment