Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   SD90_RS05540 Genome accession   NZ_CP010450
Coordinates   1104530..1105192 (-) Length   220 a.a.
NCBI ID   WP_002995626.1    Uniprot ID   A0A0H2UV22
Organism   Streptococcus pyogenes strain NGAS638     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1099530..1110192
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SD90_RS05520 (SD90_05535) - 1100099..1100326 (-) 228 WP_032462850.1 hypothetical protein -
  SD90_RS05525 (SD90_05540) sodA 1100493..1101098 (-) 606 WP_032462849.1 superoxide dismutase SodA -
  SD90_RS05530 (SD90_05545) holA 1101195..1102235 (-) 1041 WP_011054659.1 DNA polymerase III subunit delta -
  SD90_RS05535 (SD90_05550) comEC/celB 1102306..1104549 (-) 2244 WP_032462848.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  SD90_RS05540 (SD90_05555) comEA/celA/cilE 1104530..1105192 (-) 663 WP_002995626.1 ComEA family DNA-binding protein Machinery gene
  SD90_RS05545 (SD90_05560) - 1105392..1106132 (-) 741 WP_011054661.1 lysophospholipid acyltransferase family protein -
  SD90_RS05550 (SD90_05565) - 1106250..1107026 (+) 777 WP_002994360.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  SD90_RS05555 (SD90_05570) - 1107016..1107294 (+) 279 WP_002989164.1 GIY-YIG nuclease family protein -
  SD90_RS05560 (SD90_05575) - 1107318..1109318 (-) 2001 WP_032462847.1 potassium transporter Kup -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24623.45 Da        Isoelectric Point: 6.7451

>NTDB_id=121401 SD90_RS05540 WP_002995626.1 1104530..1105192(-) (comEA/celA/cilE) [Streptococcus pyogenes strain NGAS638]
MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQSKAAVPALREISPVKQQVSEEKKEIQEDNSILVDLK
GAVQKEGVYKLTASSRVRDVIELAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIFLD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=121401 SD90_RS05540 WP_002995626.1 1104530..1105192(-) (comEA/celA/cilE) [Streptococcus pyogenes strain NGAS638]
ATGTTAGACGAATTATTAATTAAAGGAAAATCGTTTTTGAGAGAGCGGTATTTTTTGCCATACCTAATTAGTCTTTTATT
AGGACTTTTTCTAATACTAAGCTTCAGTTTTTTGTTCTGGGGAAATAGGCAGAGCAAGGCAGCCGTTCCTGCTTTGAGAG
AAATATCGCCTGTGAAACAGCAGGTTAGTGAAGAAAAAAAGGAAATTCAAGAAGATAATAGTATTTTAGTGGATTTAAAA
GGCGCCGTACAAAAAGAGGGAGTTTATAAGCTAACTGCTAGCAGTCGTGTGCGAGATGTCATTGAACTAGCTGGAGGCCT
AACTTCAGAAGCTGATAAACATGCTATTAATTTTGCAGAAAAACTAACTGATGAGCAAGTTGTTTATGTACCTAAACAAG
GAGAAGAGATTTCTGTGCTACCAAGGTCATTAGTTTCTGGTAAAAAAGAAACTGCCAGCAAGGATCAGTCAAAGGTTCAT
ATTAATAAGGCCAGCTTAGAAGAACTACAACATATCCCAGGTATTGGTGCTAAAAGAGCTCAGGATATTATTGATATGAG
AGATAAGTTAGGTGGTTTTAAAGCGTTAGAAGATCTCCGTCAGGTTTCGGGGATTGGCGAAAAAACGCTCGAGAAATTAA
AAGATGACATTTTCTTGGACTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(156-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UV22

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.995

94.091

0.405

Multiple sequence alignment