Detailed information NTG0121224

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DK43_RS07860
• Genome accession: NZ_CP007573
• Coordinates: 1635255..1636310 (-)
• Length: 351 a.a.
• NCBI ID: WP_003028378.1
• Uniprot ID: A0AAI9J5V3
• Organism: Streptococcus anginosus strain SA1
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1630255..1641310

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK43_RS07830 (DK43_08020)	-	1630426..1630953 (-)	528	WP_003028371.1	Dps family protein	-
DK43_RS07835 (DK43_08025)	cclA/cilC	1631107..1631766 (+)	660	WP_037593429.1	A24 family peptidase	Machinery gene
DK43_RS10180	-	1631929..1632090 (-)	162	Protein_1564	tryptophan synthase subunit beta	-
DK43_RS07840	-	1632087..1632524 (+)	438	Protein_1565	ISL3 family transposase	-
DK43_RS07845 (DK43_08035)	-	1632913..1633443 (-)	531	WP_003028375.1	VanZ family protein	-
DK43_RS07850 (DK43_08040)	rlmN	1633436..1634518 (-)	1083	WP_022525296.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
DK43_RS07855 (DK43_08045)	-	1634552..1635115 (-)	564	WP_003043206.1	YutD family protein	-
DK43_RS07860 (DK43_08050)	sepM	1635255..1636310 (-)	1056	WP_003028378.1	SepM family pheromone-processing serine protease	Regulator
DK43_RS07865 (DK43_08055)	coaD	1636291..1636788 (-)	498	WP_003028379.1	pantetheine-phosphate adenylyltransferase	-
DK43_RS07870 (DK43_08060)	rsmD	1636778..1637326 (-)	549	WP_176601969.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DK43_RS07875 (DK43_08065)	raiA	1637517..1638059 (-)	543	WP_003028381.1	ribosome-associated translation inhibitor RaiA	-
DK43_RS07880 (DK43_08070)	-	1638140..1638805 (-)	666	WP_003028382.1	ComF family protein	-
DK43_RS07885 (DK43_08075)	comFA/cflA	1638802..1640103 (-)	1302	WP_003028383.1	DEAD/DEAH box helicase	Machinery gene
DK43_RS07890 (DK43_08080)	-	1640160..1640795 (+)	636	WP_003028384.1	YigZ family protein	-

Sequence

Protein

• Length: 351 a.a.
• Molecular weight: 38415.25 Da
• Isoelectric Point: 10.1140

>NTDB_id=121224 DK43_RS07860 WP_003028378.1 1635255..1636310(-) (sepM) [Streptococcus anginosus strain SA1]
MEKPRNKFKKWPIIAIAGLILLFLSFVVPLPYYIEVPGGAADVRQVLRVDNKEDKEKGSYNFVTVGIQHATFAHLVYAWL
TPFTDIYSAKELTGGTSDKEYMRINQFYMETSQNLAKYQGLKKAGKDITLKYLGVYVLQVTKNSTFKGILNIADTVTGVN
DKTFNSSKELIDYVGAQKIGSKVKVNYVEDGQKKSATGKIIKLENGKNGIGISLIDRTEVTSNTPIEFSTAGIGGPSAGL
MFSLAIYTQIADPTLRDGRNIAGTGSIDREGKVGDIGGIDKKVVSAAKNSAEIFFAPNNPVTKEAKKANSKAKTNYETAL
ETAKKIKTNMKIVPVKTLQDAIDYLKNTKKS

Nucleotide

• Length: 1056 bp

>NTDB_id=121224 DK43_RS07860 WP_003028378.1 1635255..1636310(-) (sepM) [Streptococcus anginosus strain SA1]
ATGGAAAAACCAAGAAATAAATTTAAAAAATGGCCGATAATTGCAATAGCAGGGCTGATTTTGCTTTTCTTATCTTTTGT
AGTTCCCTTGCCTTATTATATTGAGGTGCCAGGTGGTGCAGCAGATGTCCGTCAGGTATTGCGCGTGGACAACAAAGAAG
ATAAGGAAAAAGGTTCTTACAACTTTGTAACGGTTGGGATTCAGCATGCGACCTTTGCTCATTTGGTTTATGCTTGGTTG
ACACCTTTTACAGATATTTATTCGGCGAAGGAGTTGACTGGCGGAACTTCTGATAAAGAATACATGCGGATCAATCAGTT
TTATATGGAAACATCGCAAAACCTAGCTAAATACCAAGGGTTGAAAAAAGCTGGCAAAGATATTACTCTGAAATATCTAG
GGGTTTACGTCTTGCAAGTCACAAAGAATTCTACTTTTAAAGGCATTTTAAATATTGCAGATACTGTGACAGGTGTGAAT
GACAAGACTTTCAATAGTTCAAAAGAATTGATAGACTATGTTGGAGCGCAAAAGATTGGCAGCAAAGTCAAGGTGAACTA
TGTAGAAGACGGTCAGAAGAAATCTGCTACAGGTAAAATCATCAAACTTGAAAATGGGAAAAACGGGATTGGTATTAGCT
TGATCGACCGAACAGAAGTCACAAGCAACACACCAATTGAATTTTCAACAGCCGGTATTGGTGGACCAAGTGCGGGCTTG
ATGTTTAGTTTGGCAATTTATACGCAAATTGCAGATCCAACATTGAGAGACGGCAGAAATATTGCTGGGACGGGCTCAAT
TGACCGCGAAGGAAAAGTTGGCGACATTGGTGGGATTGACAAAAAAGTTGTTTCAGCAGCAAAAAATAGTGCAGAAATTT
TCTTTGCACCAAATAATCCAGTTACTAAGGAAGCTAAAAAAGCTAATTCTAAAGCGAAAACTAACTATGAGACCGCTTTG
GAAACTGCTAAAAAAATTAAGACCAATATGAAAATTGTACCCGTGAAAACTTTACAAGATGCCATTGATTACCTCAAGAA
CACAAAGAAGTCATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (235-300)

• PDZ domain (PDZ_2) (133-197)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	63.953	98.006	0.627