Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   DK92_RS02975 Genome accession   NZ_CP007561
Coordinates   591481..592518 (+) Length   345 a.a.
NCBI ID   WP_047235746.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NGAS596     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 586481..597518
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK92_RS02950 (DK92_03035) - 586745..588076 (+) 1332 WP_011054719.1 dipeptidase -
  DK92_RS02955 (DK92_03040) arcC 588096..589046 (+) 951 WP_011528820.1 carbamate kinase -
  DK92_RS02960 (DK92_03045) asnA 589359..590351 (+) 993 WP_002983817.1 aspartate--ammonia ligase -
  DK92_RS02965 (DK92_03050) rsmD 590474..591013 (+) 540 WP_002983819.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  DK92_RS02970 (DK92_03055) coaD 591003..591494 (+) 492 WP_002983821.1 pantetheine-phosphate adenylyltransferase -
  DK92_RS02975 (DK92_03060) sepM 591481..592518 (+) 1038 WP_047235746.1 SepM family pheromone-processing serine protease Regulator
  DK92_RS02980 (DK92_03065) - 592932..593909 (+) 978 WP_002994809.1 LacI family DNA-binding transcriptional regulator -
  DK92_RS02985 (DK92_03070) - 594357..594977 (+) 621 WP_032464468.1 YutD family protein -
  DK92_RS02990 (DK92_03075) rlmN 594981..596060 (+) 1080 WP_002992788.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  DK92_RS02995 (DK92_03080) - 596142..596768 (-) 627 WP_002983834.1 prepilin peptidase -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37555.27 Da        Isoelectric Point: 9.6692

>NTDB_id=120890 DK92_RS02975 WP_047235746.1 591481..592518(+) (sepM) [Streptococcus pyogenes strain NGAS596]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPITTVQEALVYLRK

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=120890 DK92_RS02975 WP_047235746.1 591481..592518(+) (sepM) [Streptococcus pyogenes strain NGAS596]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGGGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTATTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(233-309)

PDZ domain (PDZ_2)

(129-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

68.986

100

0.69

Multiple sequence alignment