Detailed information NTG0120880

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: DK92_RS01425
• Genome accession: NZ_CP007561
• Coordinates: 268118..269188 (+)
• Length: 356 a.a.
• NCBI ID: WP_009880666.1
• Uniprot ID: Q54910
• Organism: Streptococcus pyogenes strain NGAS596
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 263118..274188

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK92_RS01410 (DK92_01470)	amiA	263646..265616 (+)	1971	WP_047235658.1	peptide ABC transporter substrate-binding protein	Regulator
DK92_RS01415 (DK92_01475)	amiC	265681..267183 (+)	1503	WP_047235659.1	ABC transporter permease	Regulator
DK92_RS01420 (DK92_01480)	amiD	267183..268109 (+)	927	WP_002986004.1	oligopeptide ABC transporter permease OppC	Regulator
DK92_RS01425 (DK92_01485)	amiE	268118..269188 (+)	1071	WP_009880666.1	ABC transporter ATP-binding protein	Regulator
DK92_RS01430 (DK92_01490)	amiF	269181..270104 (+)	924	WP_002986000.1	ABC transporter ATP-binding protein	Regulator
DK92_RS09525	-	270142..270225 (-)	84	Protein_236	IS3 family transposase	-
DK92_RS09530	-	270359..270669 (-)	311	Protein_237	IS3 family transposase	-

Sequence

Protein

• Length: 356 a.a.
• Molecular weight: 39645.74 Da
• Isoelectric Point: 5.8952

>NTDB_id=120880 DK92_RS01425 WP_009880666.1 268118..269188(+) (amiE) [Streptococcus pyogenes strain NGAS596]
MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFVGESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQEL
TDLKTNKEWAKIRGSKIATIFQDPMTSLSPIKTIGSQITEVIIKHQKVSHAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITHDLGVVASIADKVAVMYAGEIVE
FGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAIPGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAK
TWLLHPEAPKVQKPEVIQGLHQKILRKMSQQEEGNV

Nucleotide

• Length: 1071 bp

>NTDB_id=120880 DK92_RS01425 WP_009880666.1 268118..269188(+) (amiE) [Streptococcus pyogenes strain NGAS596]
ATGACAAAAGAAAATAATGTAATCTTAACTGCCAAAGATGTGGTGGTAGAATTTGATGTGCGTGATCGTGTTTTAACAGC
TATCCGTAACGTCTCACTGGAACTTGTTGAAGGAGAAGTCCTTGCTTTTGTAGGGGAATCAGGCTCAGGTAAATCTGTTT
TAACAAAGACCTTTACAGGGATGTTGGAGTCTAATGGACGCATTGCTAATGGTTCAATTGTCTATCGTGGGCAAGAATTG
ACAGATTTAAAAACAAATAAAGAGTGGGCAAAGATTCGCGGCTCAAAAATCGCAACGATTTTCCAAGACCCAATGACCAG
TCTTAGTCCCATTAAAACTATCGGTAGCCAAATCACAGAAGTGATTATTAAGCACCAAAAAGTAAGTCATGCCAAAGCTA
AAGAAATGGCCCTTGATTACATGAATAAAGTGGGTATCCCAAATGCCAAAAAACGCTTTGAAGATTACCCATTTGAGTAT
TCAGGAGGAATGCGTCAACGTATTGTTATCGCTATTGCTTTAGCTTGTCGCCCAGATATTCTTATCTGTGATGAGCCAAC
AACAGCCCTTGATGTGACTATTCAAGCTCAAATCGTTGAGTTATTGAAGTCGCTTCAACGAGAATATCATTTCACCATTA
TCTTTATTACGCACGATTTAGGTGTTGTGGCAAGCATTGCAGATAAAGTGGCTGTCATGTATGCAGGAGAAATTGTTGAA
TTTGGAACAGTCGAAGAGATTTTCTATGATCCAAGACACCCCTATACATGGAGTTTGCTGTCTAGCTTACCGCAGTTGGC
AGATGAATCTGGTGAACTTTACGCTATTCCAGGAACGCCTCCATCACTTTATTCACCAATTATCGGAGATGCCTTTGCAC
TTCGCTCAGAATATGCTATGGTTTTAGACTTTGAAAAAGCACCTCCGGCGATTAACGTATCTGAGACTCATTGGGCCAAA
ACATGGCTTTTACACCCAGAGGCTCCAAAAGTTCAAAAACCAGAAGTCATTCAAGGTTTGCATCAAAAAATCTTAAGGAA
AATGTCACAACAGGAGGAAGGAAATGTCTGA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-299)

3D structure

• AlphaFold DB: Q54910

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	76.667	100	0.775
amiE	Streptococcus thermophilus LMG 18311	75.556	100	0.764
amiE	Streptococcus thermophilus LMD-9	75.556	100	0.764
oppD	Streptococcus mutans UA159	56.677	94.663	0.537