Detailed information
Bioinformatically predicted
Overview
| Name | radA | Type | Machinery gene |
| Locus tag | DK92_RS01175 | Genome accession | NZ_CP007561 |
| Coordinates | 211587..212948 (+) | Length | 453 a.a. |
| NCBI ID | WP_002991192.1 | Uniprot ID | Q1JNL0 |
| Organism | Streptococcus pyogenes strain NGAS596 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 174662..211506 | 211587..212948 | flank | 81 |
Gene organization within MGE regions
Location: 174662..212948
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| DK92_RS01000 (DK92_01025) | - | 174662..175858 (+) | 1197 | WP_023605215.1 | glycine betaine/L-proline ABC transporter ATP-binding protein | - |
| DK92_RS01005 (DK92_01030) | - | 175874..177601 (+) | 1728 | WP_002986341.1 | ABC transporter permease/substrate binding protein | - |
| DK92_RS01010 (DK92_01035) | polA | 177732..180374 (+) | 2643 | WP_047235631.1 | DNA polymerase I | - |
| DK92_RS01015 (DK92_01040) | - | 180561..181016 (+) | 456 | WP_002986334.1 | CoA-binding protein | - |
| DK92_RS01020 (DK92_01045) | perR | 181068..181535 (+) | 468 | WP_002986328.1 | peroxide-responsive transcriptional repressor PerR | - |
| DK92_RS01025 (DK92_01050) | - | 181754..181990 (+) | 237 | WP_014635252.1 | hypothetical protein | - |
| DK92_RS01030 (DK92_01055) | - | 182212..183546 (+) | 1335 | WP_047235632.1 | phosphoadenosine phosphosulfate reductase | - |
| DK92_RS01035 (DK92_01060) | - | 183539..184069 (+) | 531 | WP_002987925.1 | IbrB-like domain-containing protein | - |
| DK92_RS09250 | - | 184116..184265 (-) | 150 | Protein_158 | ISL3 family transposase | - |
| DK92_RS09160 | - | 184398..185548 (-) | 1151 | Protein_159 | IS3 family transposase | - |
| DK92_RS01065 (DK92_01090) | - | 185626..186936 (-) | 1311 | WP_002984130.1 | SLC13 family permease | - |
| DK92_RS01070 (DK92_01095) | nadC | 187160..188032 (+) | 873 | WP_002992869.1 | carboxylating nicotinate-nucleotide diphosphorylase | - |
| DK92_RS01075 (DK92_01100) | - | 188332..189675 (-) | 1344 | WP_168681605.1 | IS3 family transposase | - |
| DK92_RS01080 (DK92_01110) | - | 189761..190624 (-) | 864 | WP_047235635.1 | DUF975 family protein | - |
| DK92_RS09495 (DK92_01115) | - | 190661..190846 (+) | 186 | WP_002986321.1 | hypothetical protein | - |
| DK92_RS01085 (DK92_01120) | tgt | 190843..191985 (+) | 1143 | WP_011528208.1 | tRNA guanosine(34) transglycosylase Tgt | - |
| DK92_RS08795 (DK92_01125) | - | 192202..192513 (+) | 312 | WP_080262837.1 | CHY zinc finger protein | - |
| DK92_RS01090 (DK92_01130) | - | 192517..193056 (+) | 540 | WP_002986314.1 | biotin transporter BioY | - |
| DK92_RS01095 (DK92_01135) | - | 193196..193975 (+) | 780 | WP_011528209.1 | MBL fold metallo-hydrolase | - |
| DK92_RS01100 (DK92_01140) | tadA | 193975..194490 (+) | 516 | WP_002992549.1 | tRNA adenosine(34) deaminase TadA | - |
| DK92_RS01105 (DK92_01145) | - | 195104..196336 (-) | 1233 | WP_047235636.1 | transglutaminase domain-containing protein | - |
| DK92_RS01110 (DK92_01150) | speG | 196735..197439 (+) | 705 | WP_047235637.1 | streptococcal pyrogenic exotoxin SpeG | - |
| DK92_RS01115 (DK92_01160) | - | 197895..199244 (+) | 1350 | WP_014635263.1 | glucose-6-phosphate isomerase | - |
| DK92_RS01120 (DK92_01165) | - | 199593..201101 (-) | 1509 | WP_002986134.1 | helix-turn-helix domain-containing protein | - |
| DK92_RS01125 (DK92_01170) | - | 201656..202789 (+) | 1134 | WP_014635671.1 | ISAs1-like element IS1548 family transposase | - |
| DK92_RS01135 (DK92_01185) | - | 203114..203785 (+) | 672 | WP_011017305.1 | rhomboid family intramembrane serine protease | - |
| DK92_RS01140 (DK92_01190) | galU | 203884..204783 (-) | 900 | WP_002986125.1 | UTP--glucose-1-phosphate uridylyltransferase GalU | - |
| DK92_RS01145 (DK92_01195) | - | 204816..205832 (-) | 1017 | WP_002986123.1 | NAD(P)H-dependent glycerol-3-phosphate dehydrogenase | - |
| DK92_RS01150 (DK92_01200) | - | 206130..206579 (+) | 450 | WP_002986120.1 | MarR family winged helix-turn-helix transcriptional regulator | - |
| DK92_RS01155 (DK92_01205) | - | 206572..208278 (+) | 1707 | WP_031488680.1 | ABC transporter ATP-binding protein | - |
| DK92_RS01160 (DK92_01210) | - | 208281..210065 (+) | 1785 | WP_047235639.1 | ABC transporter ATP-binding protein | - |
| DK92_RS01165 (DK92_01215) | - | 210183..210950 (+) | 768 | WP_011054158.1 | epoxyqueuosine reductase QueH | - |
| DK92_RS01170 (DK92_01220) | - | 211060..211506 (+) | 447 | WP_002986111.1 | dUTP diphosphatase | - |
| DK92_RS01175 (DK92_01225) | radA | 211587..212948 (+) | 1362 | WP_002991192.1 | DNA repair protein RadA | Machinery gene |
Sequence
Protein
Download Length: 453 a.a. Molecular weight: 49358.62 Da Isoelectric Point: 6.0962
>NTDB_id=120875 DK92_RS01175 WP_002991192.1 211587..212948(+) (radA) [Streptococcus pyogenes strain NGAS596]
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRV
LGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLYASGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNAR
RTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIR
RVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKAVFS
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRV
LGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLYASGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNAR
RTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIR
RVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKAVFS
Nucleotide
Download Length: 1362 bp
>NTDB_id=120875 DK92_RS01175 WP_002991192.1 211587..212948(+) (radA) [Streptococcus pyogenes strain NGAS596]
ATGGCAAAGAAAAAAGCAACCTTTATCTGTCAGGAGTGTGGCTACCAGTCGCCAAAGTATTTAGGGCGCTGTCCAAATTG
CTCGGCCTGGTCTTCTTTTGTGGAAGAAGTAGAGGTCAAAGAAGTCAAAAATGCCCGTGTTAGTCTAGCTGGAGAAAAGT
CCAGACCGGTTAAACTAAAAGATGTGGATAATATTAGTTATCACAGAACACAGACTGACATGTCTGAATTTAATAGAGTT
CTTGGAGGGGGTGTGGTTCCTGGAAGCTTGATTTTAATTGGTGGTGATCCAGGTATTGGAAAATCCACCTTACTCTTGCA
GGTATCTACGCAGCTCGCTAATAAGGGAACGGTTCTCTATGCGTCTGGGGAAGAATCAGCAGAGCAGATTAAACTGCGGA
GTGAGCGTCTGGGTGATATTGACAATGAATTTTACCTCTATGCCGAAACCAATATGCAAGCTATTCGCACAGAAATTGAA
AATATTAAACCAGATTTTTTAATTATTGACTCCATTCAGACCATCATGAGCCCTGATATTACAGGTGTTCAAGGATCAGT
CAGTCAGGTGAGAGAAGTCACTGCAGAATTGATGCAGCTTGCAAAGACGAACAACATTGCAACCTTTATTGTGGGTCATG
TCACCAAGGAAGGAACCTTGGCTGGGCCTCGTATGTTAGAACACATGGTGGATACCGTTCTCTACTTTGAAGGGGAAAGG
CATCACACCTTTCGCATTCTTCGGGCTGTGAAAAACCGCTTTGGCTCCACTAACGAGATTGGCATCTTTGAAATGCAGTC
TGGCGGCTTGGTAGAGGTCTTAAATCCTAGTCAAGTCTTTTTAGAGGAACGCTTAGATGGGGCAACAGGATCGGCTGTCG
TTGTAACGATGGAAGGAAGTCGTCCTATCTTAGCAGAGGTGCAATCTTTAGTGACACCAACCGTTTTTGGCAATGCCAGA
CGAACCACTACGGGACTTGATTTCAATCGCGTAAGCCTAATAATGGCAGTTTTAGAAAAGCGTTGTGGTTTACTCTTACA
AAATCAAGATGCCTACCTCAAGTCGGCTGGTGGTGTCAAACTAGACGAACCTGCCATTGATTTGGCAGTCGCTGTGGCTA
TCGCATCCAGTTATAAGGAAAAACCAACCAGCCCTCAAGAAGCTTTCTTAGGCGAGATCGGGTTAACAGGTGAGATTCGG
CGAGTGACCCGTATTGAGCAACGGATTAATGAAGCAGCAAAGCTTGGCTTTACCAAGGTCTATGCTCCTAAAAATGCCTT
GCAAGGCATTGATATCCCTCAAGGTATTGAGGTTGTTGGAGTGACTACGGTTGGTCAGGTTTTAAAGGCAGTTTTTAGCT
AG
ATGGCAAAGAAAAAAGCAACCTTTATCTGTCAGGAGTGTGGCTACCAGTCGCCAAAGTATTTAGGGCGCTGTCCAAATTG
CTCGGCCTGGTCTTCTTTTGTGGAAGAAGTAGAGGTCAAAGAAGTCAAAAATGCCCGTGTTAGTCTAGCTGGAGAAAAGT
CCAGACCGGTTAAACTAAAAGATGTGGATAATATTAGTTATCACAGAACACAGACTGACATGTCTGAATTTAATAGAGTT
CTTGGAGGGGGTGTGGTTCCTGGAAGCTTGATTTTAATTGGTGGTGATCCAGGTATTGGAAAATCCACCTTACTCTTGCA
GGTATCTACGCAGCTCGCTAATAAGGGAACGGTTCTCTATGCGTCTGGGGAAGAATCAGCAGAGCAGATTAAACTGCGGA
GTGAGCGTCTGGGTGATATTGACAATGAATTTTACCTCTATGCCGAAACCAATATGCAAGCTATTCGCACAGAAATTGAA
AATATTAAACCAGATTTTTTAATTATTGACTCCATTCAGACCATCATGAGCCCTGATATTACAGGTGTTCAAGGATCAGT
CAGTCAGGTGAGAGAAGTCACTGCAGAATTGATGCAGCTTGCAAAGACGAACAACATTGCAACCTTTATTGTGGGTCATG
TCACCAAGGAAGGAACCTTGGCTGGGCCTCGTATGTTAGAACACATGGTGGATACCGTTCTCTACTTTGAAGGGGAAAGG
CATCACACCTTTCGCATTCTTCGGGCTGTGAAAAACCGCTTTGGCTCCACTAACGAGATTGGCATCTTTGAAATGCAGTC
TGGCGGCTTGGTAGAGGTCTTAAATCCTAGTCAAGTCTTTTTAGAGGAACGCTTAGATGGGGCAACAGGATCGGCTGTCG
TTGTAACGATGGAAGGAAGTCGTCCTATCTTAGCAGAGGTGCAATCTTTAGTGACACCAACCGTTTTTGGCAATGCCAGA
CGAACCACTACGGGACTTGATTTCAATCGCGTAAGCCTAATAATGGCAGTTTTAGAAAAGCGTTGTGGTTTACTCTTACA
AAATCAAGATGCCTACCTCAAGTCGGCTGGTGGTGTCAAACTAGACGAACCTGCCATTGATTTGGCAGTCGCTGTGGCTA
TCGCATCCAGTTATAAGGAAAAACCAACCAGCCCTCAAGAAGCTTTCTTAGGCGAGATCGGGTTAACAGGTGAGATTCGG
CGAGTGACCCGTATTGAGCAACGGATTAATGAAGCAGCAAAGCTTGGCTTTACCAAGGTCTATGCTCCTAAAAATGCCTT
GCAAGGCATTGATATCCCTCAAGGTATTGAGGTTGTTGGAGTGACTACGGTTGGTCAGGTTTTAAAGGCAGTTTTTAGCT
AG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| radA | Streptococcus mitis NCTC 12261 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae D39 |
85.43 |
100 |
0.854 |
| radA | Streptococcus pneumoniae R6 |
85.43 |
100 |
0.854 |
| radA | Streptococcus pneumoniae Rx1 |
85.43 |
100 |
0.854 |
| radA | Streptococcus mitis SK321 |
85.43 |
100 |
0.854 |
| radA | Streptococcus pneumoniae TIGR4 |
85.43 |
100 |
0.854 |
| radA | Bacillus subtilis subsp. subtilis str. 168 |
61.369 |
100 |
0.614 |