Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   DI45_RS06965 Genome accession   NZ_CP007560
Coordinates   1334772..1335809 (-) Length   345 a.a.
NCBI ID   WP_047235395.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NGAS743     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1329772..1340809
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DI45_RS06945 (DI45_07225) - 1330522..1331148 (+) 627 WP_002983834.1 prepilin peptidase -
  DI45_RS06950 (DI45_07230) rlmN 1331230..1332309 (-) 1080 WP_002992788.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  DI45_RS06955 (DI45_07235) - 1332313..1332933 (-) 621 WP_002992791.1 YutD family protein -
  DI45_RS06960 (DI45_07240) - 1333381..1334358 (-) 978 WP_002994809.1 LacI family DNA-binding transcriptional regulator -
  DI45_RS06965 (DI45_07245) sepM 1334772..1335809 (-) 1038 WP_047235395.1 SepM family pheromone-processing serine protease Regulator
  DI45_RS06970 (DI45_07250) coaD 1335796..1336287 (-) 492 WP_002983821.1 pantetheine-phosphate adenylyltransferase -
  DI45_RS06975 (DI45_07255) rsmD 1336277..1336816 (-) 540 WP_002983819.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  DI45_RS06980 (DI45_07260) asnA 1336939..1337931 (-) 993 WP_002994813.1 aspartate--ammonia ligase -
  DI45_RS06985 (DI45_07265) arcC 1338244..1339194 (-) 951 WP_002994815.1 carbamate kinase -
  DI45_RS06990 (DI45_07270) - 1339214..1340545 (-) 1332 WP_047235396.1 dipeptidase -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37569.30 Da        Isoelectric Point: 9.6692

>NTDB_id=120850 DI45_RS06965 WP_047235395.1 1334772..1335809(-) (sepM) [Streptococcus pyogenes strain NGAS743]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTIQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPITTVQEALVYLRK

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=120850 DI45_RS06965 WP_047235395.1 1334772..1335809(-) (sepM) [Streptococcus pyogenes strain NGAS743]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGTAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGCAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGATTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTATTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(233-309)

PDZ domain (PDZ_2)

(129-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

68.696

100

0.687

Multiple sequence alignment