Detailed information NTG0120845

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: DI45_RS05430
• Genome accession: NZ_CP007560
• Coordinates: 1044352..1045581 (-)
• Length: 409 a.a.
• NCBI ID: WP_032464958.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NGAS743
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1039352..1050581

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DI45_RS05410 (DI45_05630)	rpiA	1039634..1040317 (-)	684	WP_020905094.1	ribose-5-phosphate isomerase RpiA	-
DI45_RS05415 (DI45_05635)	-	1040695..1042794 (+)	2100	WP_030127660.1	AAA family ATPase	-
DI45_RS05420 (DI45_05640)	-	1042852..1043595 (-)	744	WP_002984942.1	hypothetical protein	-
DI45_RS05425 (DI45_05645)	yihA	1043743..1044342 (-)	600	WP_002984945.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
DI45_RS05430 (DI45_05650)	clpX	1044352..1045581 (-)	1230	WP_032464958.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
DI45_RS09940 (DI45_05655)	-	1045711..1045881 (-)	171	WP_002990165.1	hypothetical protein	-
DI45_RS05440 (DI45_05660)	-	1045901..1046398 (-)	498	WP_002984955.1	dihydrofolate reductase	-
DI45_RS05445 (DI45_05665)	-	1046478..1047317 (-)	840	WP_047235334.1	thymidylate synthase	-
DI45_RS05450 (DI45_05670)	-	1047526..1048701 (+)	1176	WP_021299369.1	hydroxymethylglutaryl-CoA synthase	-
DI45_RS05455 (DI45_05675)	-	1048688..1049965 (+)	1278	WP_047235335.1	hydroxymethylglutaryl-CoA reductase, degradative	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45033.57 Da
• Isoelectric Point: 4.6616

>NTDB_id=120845 DI45_RS05430 WP_032464958.1 1044352..1045581(-) (clpX) [Streptococcus pyogenes strain NGAS743]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLKTSDLIRI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=120845 DI45_RS05430 WP_032464958.1 1044352..1045581(-) (clpX) [Streptococcus pyogenes strain NGAS743]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGTCGTTTACCAGTTGTGGCAGCTCTTGAACAACTTAAAACATCAGATTTGATTCGAATC
TTAACAGAACCAAGAAATGCCCTGGTCAAGCAATATCAGGCCCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CGATGTTAGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.998	100	0.89
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575