Detailed information NTG0120697

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: X998_RS12925
• Genome accession: NZ_CP007539
• Coordinates: 2487287..2488174 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain FDAARGOS_5
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2482287..2493174

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
X998_RS12895 (X998_2612)	-	2483019..2483780 (+)	762	WP_000323455.1	alpha/beta hydrolase	-
X998_RS12900 (X998_2611)	-	2484025..2484480 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
X998_RS14820 (X998_03255)	-	2484602..2484703 (+)	102	WP_000731972.1	SE2200 family small protein	-
X998_RS12910 (X998_2610)	-	2484763..2486187 (-)	1425	WP_000953744.1	alkaline phosphatase	-
X998_RS12915 (X998_2609)	-	2486385..2486585 (+)	201	WP_000604728.1	hypothetical protein	-
X998_RS12920 (X998_2608)	braR	2486611..2487276 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
X998_RS12925 (X998_2607)	braS	2487287..2488174 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
X998_RS12930 (X998_2606)	-	2488282..2489037 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
X998_RS12935 (X998_2605)	-	2489034..2491034 (+)	2001	WP_000776751.1	ABC transporter permease	-
X998_RS12940 (X998_03260)	-	2491693..2491806 (+)	114	WP_011447078.1	hypothetical protein	-
X998_RS12950 (X998_03270)	-	2492188..2492448 (+)	261	WP_001789910.1	hypothetical protein	-
X998_RS12955 (X998_2603)	-	2492458..2492955 (+)	498	WP_001065268.1	glutathione peroxidase	-
X998_RS12960 (X998_03275)	-	2493063..2493155 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=120697 X998_RS12925 WP_000143419.1 2487287..2488174(+) (braS) [Staphylococcus aureus strain FDAARGOS_5]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=120697 X998_RS12925 WP_000143419.1 2487287..2488174(+) (braS) [Staphylococcus aureus strain FDAARGOS_5]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997