Detailed information NTG0120659

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: X998_RS02085
• Genome accession: NZ_CP007539
• Coordinates: 377915..378958 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain FDAARGOS_5
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 372915..383958

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
X998_RS02040 (X998_03790)	-	373344..373454 (+)	111	WP_001790257.1	hypothetical protein	-
X998_RS02045 (X998_1945)	-	373483..373896 (+)	414	WP_001549145.1	hypothetical protein	-
X998_RS02055 (X998_1944)	-	374327..375313 (-)	987	WP_000999713.1	FUSC family protein	-
X998_RS02070 (X998_1943)	map	375841..376599 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
X998_RS02075 (X998_1942)	-	376816..377202 (+)	387	WP_001110179.1	hypothetical protein	-
X998_RS02080 (X998_1941)	liaF	377217..377918 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
X998_RS02085 (X998_1940)	vraS	377915..378958 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
X998_RS02090 (X998_1939)	vraR	378948..379577 (+)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
X998_RS02095 (X998_1938)	-	379693..380910 (-)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
X998_RS02100 (X998_1937)	-	381188..381463 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
X998_RS02105 (X998_1936)	-	381470..381934 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
X998_RS02110 (X998_1935)	-	382081..382281 (+)	201	WP_000180461.1	DUF1128 family protein	-
X998_RS02115 (X998_1934)	-	382284..383540 (+)	1257	WP_001795438.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=120659 X998_RS02085 WP_001017131.1 377915..378958(+) (vraS) [Staphylococcus aureus strain FDAARGOS_5]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=120659 X998_RS02085 WP_001017131.1 377915..378958(+) (vraS) [Staphylococcus aureus strain FDAARGOS_5]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1