Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   NMA510612_RS04590 Genome accession   NZ_CP007524
Coordinates   888816..891035 (+) Length   739 a.a.
NCBI ID   WP_153063192.1    Uniprot ID   -
Organism   Neisseria meningitidis strain 510612     
Function   DNA processing; DNA transport into the cytoplasm (predicted from homology)   
DNA processing DNA binding and uptake

Genomic Context

Location: 883816..896035
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMA510612_RS15530 - 888543..888734 (-) 192 Protein_871 hypothetical protein -
  NMA510612_RS04590 (NMA510612_1015) comA 888816..891035 (+) 2220 WP_153063192.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  NMA510612_RS04595 (NMA510612_1017) comL 891093..891896 (-) 804 WP_002221259.1 outer membrane protein assembly factor BamD Machinery gene
  NMA510612_RS04600 (NMA510612_1016) rluD 891895..893019 (+) 1125 WP_002246063.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD -
  NMA510612_RS04605 (NMA510612_1019) - 893172..894119 (-) 948 WP_002246064.1 bile acid:sodium symporter family protein -
  NMA510612_RS15535 - 894338..894511 (-) 174 Protein_876 IS5/IS1182 family transposase -
  NMA510612_RS04610 (NMA510612_1022) pgeF 894678..895457 (+) 780 WP_002246066.1 peptidoglycan editing factor PgeF -
  NMA510612_RS04615 (NMA510612_1023) lptE 895509..895988 (+) 480 WP_002214127.1 LPS assembly lipoprotein LptE -

Sequence

Protein


Download         Length: 739 a.a.        Molecular weight: 79936.73 Da        Isoelectric Point: 10.2085

>NTDB_id=120308 NMA510612_RS04590 WP_153063192.1 888816..891035(+) (comA) [Neisseria meningitidis strain 510612]
MFRRWFLPCWVVGAAASFALPVVPHWLFWLAAFAVFAVFARRFAFAGLMLCVLAGAAYGVFRTEAALSSQWRAEAVSGVP
LTVEVADMPRSDGRRVQFAAKAVDSGGRTFDLLLSDYKRREWAVGSRWRITARVHPVVGELNLRGLNREAWALSNGIGGA
GTVGADRVLLHDGSGWGIAVWRSRISRNWQQADADGGLSDGIGLMRALSVGEQSALRPELWQAFRPLGLTHLVSISGLHV
TMVAVMFAWLAKRLLACSPRLPARPRVWVLAAGCAGALFYALLAGFSVPTQRSVLMLAAFAWAWRRGRLSAWATWWQALA
AVLLFDPSAVLGVGTWLSFGLVAALIWACSGRLHEGKRQTALRGQWAASVLSLVLLGYLFASLPLISPLVNAVAIPWFSW
VLTPLALLGSVVPFAPLQQAAAFLAEYTLRFLVWLAGVSPEFAVAAAPLPLLVLAVCAALLLLLPRGLGLRPWAVLLLAG
FVFYRPPSVPENEAAVTVWDAGQGLSVSVQTANHHLLFDTGTAAAAQMGIVPSLNAAGVRRLDKLVLSHHDSDHDGGFQA
VGKIPNGGIYAGQPEFYEGARHCAEQRWQWDGVDFEFLMPSERKNIDDNGKSCVLRVVAGGAALLVTGDLDTKGEAELVK
KYGSNLYSQVLVLGHHGSNTSSSGLFLHTVAPEYAVASSGYANAYKHPTEAVQNRVRAHGIKLLRTDLSGALQFGLGRGG
VKAQRLRGYKFYWQKKPFE

Nucleotide


Download         Length: 2220 bp        

>NTDB_id=120308 NMA510612_RS04590 WP_153063192.1 888816..891035(+) (comA) [Neisseria meningitidis strain 510612]
GTGTTCCGTCGTTGGTTTTTGCCGTGTTGGGTTGTCGGCGCGGCGGCTTCGTTTGCGCTGCCGGTCGTGCCGCATTGGCT
GTTTTGGCTGGCGGCTTTTGCGGTTTTTGCTGTGTTTGCAAGGCGTTTTGCGTTTGCCGGTCTGATGCTGTGCGTGTTGG
CGGGCGCGGCTTACGGCGTATTCAGGACGGAGGCGGCATTGTCTTCGCAATGGCGGGCGGAGGCGGTTTCAGGCGTGCCT
TTGACAGTGGAAGTGGCGGATATGCCGAGGTCGGACGGGCGGCGCGTGCAGTTTGCGGCAAAGGCTGTGGACAGCGGTGG
TCGGACGTTTGATTTGCTGCTGTCGGACTACAAACGGCGCGAATGGGCGGTCGGGAGCAGATGGCGGATAACGGCACGTG
TGCACCCCGTCGTCGGGGAGTTGAACCTGCGCGGTTTGAACCGTGAGGCGTGGGCATTATCCAACGGGATAGGCGGCGCG
GGGACGGTCGGTGCGGACAGGGTTTTGCTGCATGACGGAAGCGGTTGGGGGATTGCGGTTTGGCGCAGCCGCATCAGCCG
TAATTGGCAGCAGGCGGATGCGGACGGCGGGCTTTCAGACGGCATCGGGCTGATGCGCGCGTTGAGCGTGGGCGAACAGT
CGGCATTGCGCCCCGAATTGTGGCAGGCGTTCCGGCCGTTGGGGCTGACGCATTTGGTCAGTATTTCGGGTTTGCACGTT
ACGATGGTGGCGGTGATGTTTGCGTGGCTGGCGAAGCGGCTGCTTGCCTGTTCCCCGCGCCTTCCTGCCCGGCCGCGCGT
GTGGGTTTTGGCGGCGGGGTGTGCAGGCGCGCTGTTTTACGCGCTGCTTGCCGGTTTTTCCGTGCCGACGCAGCGCAGTG
TTTTGATGTTGGCGGCGTTTGCGTGGGCTTGGCGTAGGGGAAGACTGTCGGCGTGGGCGACGTGGTGGCAGGCGTTGGCG
GCGGTGCTGCTGTTCGACCCGTCGGCGGTCTTGGGTGTGGGGACTTGGCTGTCTTTTGGTTTGGTGGCGGCCCTGATATG
GGCGTGTTCGGGGCGTTTGCACGAGGGGAAACGGCAAACTGCTTTGCGCGGGCAGTGGGCGGCTTCGGTGTTGTCGTTGG
TTTTGCTCGGTTATCTGTTTGCTTCGCTGCCTTTAATCAGCCCTTTGGTCAATGCGGTGGCGATTCCGTGGTTTTCTTGG
GTATTGACGCCGCTGGCGTTGCTGGGTTCGGTCGTGCCGTTTGCGCCGCTTCAGCAGGCGGCAGCATTCTTGGCAGAATA
TACTTTGAGGTTTTTGGTATGGCTTGCCGGTGTGTCGCCGGAGTTTGCCGTTGCCGCCGCACCTTTGCCGCTGCTGGTGT
TGGCGGTGTGTGCCGCTTTGCTGTTGTTGCTGCCGCGCGGCTTGGGTTTGCGTCCGTGGGCGGTGTTGCTGTTGGCAGGG
TTTGTGTTTTACCGTCCGCCCAGCGTGCCGGAAAATGAGGCTGCGGTTACGGTTTGGGATGCGGGGCAGGGTTTGTCGGT
GTCGGTTCAGACGGCAAATCATCATCTTTTGTTTGACACCGGAACGGCAGCGGCGGCGCAGATGGGGATTGTGCCGAGTT
TGAATGCGGCGGGTGTCCGCCGTTTGGACAAGCTGGTTCTGTCGCATCACGACAGCGACCACGACGGCGGTTTTCAGGCA
GTCGGCAAGATACCGAACGGCGGGATTTATGCCGGGCAGCCAGAATTTTATGAGGGGGCGCGGCATTGTGCGGAACAGCG
TTGGCAATGGGACGGCGTGGATTTCGAGTTTTTGATGCCGTCTGAACGCAAAAACATCGATGATAATGGGAAAAGTTGTG
TTTTGCGTGTTGTGGCTGGTGGTGCGGCACTGCTGGTAACGGGCGATTTGGATACGAAAGGCGAGGCGGAGTTGGTTAAA
AAATACGGCTCAAACCTGTACAGCCAGGTGTTGGTATTGGGGCATCACGGCAGCAATACTTCATCATCAGGGTTGTTTTT
GCATACGGTCGCACCGGAATATGCGGTAGCGTCAAGCGGTTATGCCAACGCCTACAAACATCCGACCGAAGCGGTGCAGA
ACCGTGTCCGCGCACACGGCATCAAACTGCTGCGTACCGATTTGTCGGGCGCGCTGCAATTCGGCTTGGGGCGCGGCGGC
GTGAAGGCTCAACGTTTGAGAGGGTATAAATTCTATTGGCAGAAAAAACCGTTTGAATGA

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(8-167)

Metallo-beta-lactamase superfamily (Lactamase_B)

(501-677)

Competence protein (Competence)

(208-465)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Neisseria gonorrhoeae MS11

94.587

100

0.946

Multiple sequence alignment