Detailed information NTG0120307

Bioinformatically predicted

Overview

• Name: tpc
• Type: Machinery gene
• Locus tag: NMA510612_RS04535
• Genome accession: NZ_CP007524
• Coordinates: 874588..875586 (-)
• Length: 332 a.a.
• NCBI ID: WP_002214152.1
• Uniprot ID: X5F838
• Organism: Neisseria meningitidis strain 510612
• Function: DNA processing; DNA transport into the cytoplasm (predicted from homology) DNA processing DNA binding and uptake

Genomic Context

Location: 869588..880586

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NMA510612_RS04515 (NMA510612_0998)	-	871069..871695 (-)	627	WP_002246057.1	phosphoribosylanthranilate isomerase	-
NMA510612_RS04520 (NMA510612_0999)	greB	871754..872245 (-)	492	WP_002236813.1	transcription elongation factor GreB	-
NMA510612_RS04525 (NMA510612_1000)	purF	872345..873889 (-)	1545	WP_002246058.1	amidophosphoribosyltransferase	-
NMA510612_RS04530 (NMA510612_1002)	-	874098..874595 (-)	498	WP_002237644.1	CvpA family protein	-
NMA510612_RS04535 (NMA510612_1003)	tpc	874588..875586 (-)	999	WP_002214152.1	cell division protein FtsN	Machinery gene
NMA510612_RS04540 (NMA510612_1004)	folC	875599..876873 (-)	1275	WP_002246059.1	bifunctional tetrahydrofolate synthase/dihydrofolate synthase	-
NMA510612_RS04545 (NMA510612_1005)	-	876904..877350 (-)	447	WP_002246060.1	protein YgfX	-
NMA510612_RS04550 (NMA510612_1006)	-	877355..877714 (-)	360	WP_002233690.1	hypothetical protein	-
NMA510612_RS04555 (NMA510612_1007)	-	877787..878515 (-)	729	WP_002233691.1	amino acid ABC transporter ATP-binding protein	-
NMA510612_RS04565 (NMA510612_1010)	rsmA	878688..879467 (-)	780	WP_002249638.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
NMA510612_RS04570 (NMA510612_1011)	-	879664..880353 (+)	690	WP_002226537.1	uracil-DNA glycosylase family protein	-

Sequence

Protein

• Length: 332 a.a.
• Molecular weight: 35520.89 Da
• Isoelectric Point: 10.1759

>NTDB_id=120307 NMA510612_RS04535 WP_002214152.1 874588..875586(-) (tpc) [Neisseria meningitidis strain 510612]
MSENKQNEVLSGYEQLKRRNRRRLVTASCLVAASCILLAAALSSGPAEQTAGETSGVENKAAGAAQTPALKSAADKPQDL
AGEDKPSAADSEISEPENVGAPLVLINDRLEDSNIKGLEASEKLQQAETAKTAPKQAKQRAAEKVPATADSTDTVAVEKP
KRTAETKPQKAERTAKAKPKAKETKTAEKVADKPKTAAEKTKPDTAKSDSAVKEAKKADKAESKKTAEKDRSDGKKHETA
QKTDKADKTKTAEKEKSGKKAAIQAGYAEKERALSLQRKMKAAGIDSTITEIMTDNGKVYRVKSSNYKNARDAERDLNKL
RVHGIAGQVTNE

Nucleotide

• Length: 999 bp

>NTDB_id=120307 NMA510612_RS04535 WP_002214152.1 874588..875586(-) (tpc) [Neisseria meningitidis strain 510612]
ATGTCCGAAAACAAACAAAACGAAGTCCTGAGCGGTTACGAACAACTCAAACGGCGCAACCGCCGCCGCCTCGTAACGGC
AAGTTGCCTGGTTGCCGCCTCCTGCATCCTGCTGGCAGCCGCCCTCAGTTCCGGCCCTGCCGAACAGACTGCCGGCGAAA
CAAGCGGCGTAGAAAACAAAGCGGCAGGTGCGGCACAAACCCCTGCCTTGAAATCCGCCGCCGACAAACCGCAGGACTTG
GCAGGCGAAGACAAGCCTTCTGCCGCCGACAGCGAAATCAGCGAGCCTGAAAACGTAGGCGCGCCGCTGGTGCTGATTAA
CGACCGCCTCGAAGACAGCAACATCAAAGGTTTGGAAGCATCCGAGAAACTGCAACAGGCAGAAACCGCCAAAACCGCAC
CGAAGCAGGCAAAACAACGCGCTGCCGAAAAAGTGCCGGCAACTGCCGACAGTACGGATACGGTAGCGGTTGAAAAACCG
AAACGCACTGCCGAAACAAAACCGCAAAAAGCGGAACGCACTGCCAAAGCCAAGCCCAAAGCCAAAGAAACCAAAACCGC
CGAAAAAGTTGCCGACAAACCGAAAACTGCCGCCGAAAAAACCAAACCGGATACGGCAAAATCCGACAGCGCGGTAAAAG
AAGCGAAAAAAGCCGACAAGGCTGAAAGCAAAAAAACAGCCGAAAAAGACCGTTCGGACGGCAAAAAACACGAAACGGCA
CAAAAAACCGACAAAGCGGACAAGACCAAAACCGCCGAGAAGGAAAAATCCGGTAAAAAAGCCGCCATTCAGGCAGGTTA
TGCCGAAAAAGAACGCGCCTTAAGCCTCCAGCGCAAAATGAAGGCGGCGGGTATCGATTCGACCATCACCGAAATTATGA
CCGACAACGGCAAAGTTTACCGCGTCAAATCAAGCAACTATAAAAACGCAAGGGATGCCGAACGCGATTTGAACAAATTG
CGCGTACACGGTATCGCCGGTCAGGTAACGAATGAATAA

Domains

Predicted by InterproScan.

• SPOR domain (SPOR) (259-330)

3D structure

• AlphaFold DB: X5F838

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
tpc	Neisseria gonorrhoeae MS11	89.884	100	0.937