Detailed information NTG0120030

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: CH51_RS14870
• Genome accession: NZ_CP007499
• Coordinates: 2854437..2855324 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain 2395 USA500
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2849437..2860324

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CH51_RS14835	-	2849456..2849548 (+)	93	WP_010956583.1	hypothetical protein	-
CH51_RS14840 (CH51_13980)	-	2849656..2850153 (-)	498	WP_001065268.1	glutathione peroxidase	-
CH51_RS14845	-	2850163..2850423 (-)	261	WP_001789910.1	hypothetical protein	-
CH51_RS14850	-	2850805..2850918 (-)	114	WP_011447078.1	hypothetical protein	-
CH51_RS14860 (CH51_13985)	-	2851577..2853577 (-)	2001	WP_000776751.1	ABC transporter permease	-
CH51_RS14865 (CH51_13990)	-	2853574..2854329 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
CH51_RS14870 (CH51_13995)	braS	2854437..2855324 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
CH51_RS14875 (CH51_14000)	braR	2855335..2856000 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
CH51_RS14880 (CH51_14005)	-	2856026..2856226 (-)	201	WP_000604728.1	hypothetical protein	-
CH51_RS14890 (CH51_14010)	-	2856424..2857848 (+)	1425	WP_000953744.1	alkaline phosphatase	-
CH51_RS16800	-	2857908..2858009 (-)	102	WP_000731972.1	SE2200 family small protein	-
CH51_RS14895 (CH51_14020)	-	2858131..2858586 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
CH51_RS14900 (CH51_14025)	-	2858831..2859592 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=120030 CH51_RS14870 WP_000143419.1 2854437..2855324(-) (braS) [Staphylococcus aureus strain 2395 USA500]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=120030 CH51_RS14870 WP_000143419.1 2854437..2855324(-) (braS) [Staphylococcus aureus strain 2395 USA500]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997