Detailed information
Bioinformatically predicted
Overview
| Name | clpC | Type | Regulator |
| Locus tag | ZY05719_RS09315 | Genome accession | NZ_CP007497 |
| Coordinates | 1877892..1880345 (-) | Length | 817 a.a. |
| NCBI ID | WP_012027858.1 | Uniprot ID | A0A2K1SY42 |
| Organism | Streptococcus suis strain ZY05719 isolate diseased pig | ||
| Function | degradation of ComW (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 1873994..1917221 | 1877892..1880345 | within | 0 |
Gene organization within MGE regions
Location: 1873994..1917221
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ZY05719_RS09295 (ZY05719_09345) | dusB | 1873994..1874998 (+) | 1005 | WP_012775355.1 | tRNA dihydrouridine synthase DusB | - |
| ZY05719_RS09300 (ZY05719_09350) | - | 1875144..1875917 (-) | 774 | WP_012027854.1 | NUDIX domain-containing protein | - |
| ZY05719_RS09305 (ZY05719_09355) | pnuC | 1875910..1876731 (-) | 822 | WP_012027855.1 | nicotinamide riboside transporter PnuC | - |
| ZY05719_RS09310 (ZY05719_09360) | - | 1876741..1877778 (-) | 1038 | WP_012028524.1 | AAA family ATPase | - |
| ZY05719_RS09315 (ZY05719_09365) | clpC | 1877892..1880345 (-) | 2454 | WP_012027858.1 | ATP-dependent Clp protease ATP-binding subunit | Regulator |
| ZY05719_RS09320 (ZY05719_09370) | - | 1880351..1880809 (-) | 459 | WP_012027859.1 | CtsR family transcriptional regulator | - |
| ZY05719_RS09325 (ZY05719_09375) | - | 1880959..1881297 (+) | 339 | WP_012027860.1 | thioredoxin domain-containing protein | - |
| ZY05719_RS09330 (ZY05719_09380) | - | 1881297..1881998 (+) | 702 | WP_012027861.1 | hypothetical protein | - |
| ZY05719_RS09335 (ZY05719_09385) | tsf | 1882261..1883301 (-) | 1041 | WP_012027862.1 | translation elongation factor Ts | - |
| ZY05719_RS09340 (ZY05719_09390) | rpsB | 1883457..1884233 (-) | 777 | WP_012775356.1 | 30S ribosomal protein S2 | - |
| ZY05719_RS09345 (ZY05719_09395) | - | 1884580..1885092 (-) | 513 | WP_012027864.1 | adenylate kinase | - |
| ZY05719_RS09355 (ZY05719_09405) | - | 1885746..1890824 (-) | 5079 | WP_012775357.1 | S8 family serine peptidase | - |
| ZY05719_RS09360 (ZY05719_09410) | nusG | 1890968..1891507 (-) | 540 | WP_002940254.1 | transcription termination/antitermination protein NusG | - |
| ZY05719_RS09365 (ZY05719_09415) | secE | 1891617..1891793 (-) | 177 | WP_002940255.1 | preprotein translocase subunit SecE | - |
| ZY05719_RS09370 | rpmG | 1891803..1891955 (-) | 153 | WP_002940258.1 | 50S ribosomal protein L33 | - |
| ZY05719_RS09375 (ZY05719_09420) | pbp2a | 1891989..1894202 (-) | 2214 | WP_012027868.1 | penicillin-binding protein PBP2A | - |
| ZY05719_RS09380 (ZY05719_09425) | - | 1894355..1895323 (+) | 969 | WP_012027869.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| ZY05719_RS09385 (ZY05719_09430) | - | 1895325..1896191 (+) | 867 | WP_012027870.1 | RluA family pseudouridine synthase | - |
| ZY05719_RS09390 (ZY05719_09435) | purR | 1896218..1897030 (-) | 813 | WP_002938438.1 | pur operon repressor | - |
| ZY05719_RS09395 (ZY05719_09440) | - | 1897132..1897998 (-) | 867 | WP_012027872.1 | aminoglycoside phosphotransferase family protein | - |
| ZY05719_RS09400 (ZY05719_09445) | - | 1897998..1898939 (-) | 942 | WP_012775359.1 | 3'-5' exoribonuclease YhaM family protein | - |
| ZY05719_RS09405 (ZY05719_09450) | - | 1898929..1900167 (-) | 1239 | WP_012027874.1 | DNA recombination protein RmuC | - |
| ZY05719_RS09410 (ZY05719_09455) | - | 1900168..1900800 (-) | 633 | WP_012027875.1 | thiamine diphosphokinase | - |
| ZY05719_RS09415 (ZY05719_09460) | rpe | 1900793..1901452 (-) | 660 | WP_012027876.1 | ribulose-phosphate 3-epimerase | - |
| ZY05719_RS09420 (ZY05719_09465) | rsgA | 1901467..1902342 (-) | 876 | WP_012027877.1 | ribosome small subunit-dependent GTPase A | - |
| ZY05719_RS09430 (ZY05719_09475) | - | 1903239..1904816 (-) | 1578 | WP_012027878.1 | ATP-binding cassette domain-containing protein | - |
| ZY05719_RS09435 (ZY05719_09480) | - | 1904813..1906054 (-) | 1242 | WP_014636518.1 | radical SAM protein | - |
| ZY05719_RS09440 (ZY05719_09490) | - | 1906423..1907286 (-) | 864 | WP_012027880.1 | helix-turn-helix domain-containing protein | - |
| ZY05719_RS09450 (ZY05719_09495) | - | 1907776..1910220 (-) | 2445 | WP_012027881.1 | LTA synthase family protein | - |
| ZY05719_RS09455 (ZY05719_09500) | - | 1910233..1911963 (-) | 1731 | WP_012775361.1 | membrane protein | - |
| ZY05719_RS09460 (ZY05719_09505) | rsmA | 1912328..1913200 (-) | 873 | WP_012775362.1 | 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA | - |
| ZY05719_RS09465 (ZY05719_09510) | - | 1913220..1913750 (-) | 531 | WP_009910909.1 | DUF1697 domain-containing protein | - |
| ZY05719_RS09470 (ZY05719_09515) | - | 1913764..1914021 (-) | 258 | WP_012775363.1 | Txe/YoeB family addiction module toxin | - |
| ZY05719_RS09475 (ZY05719_09520) | - | 1914023..1914283 (-) | 261 | WP_002939010.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| ZY05719_RS09480 (ZY05719_09525) | - | 1914359..1914814 (-) | 456 | WP_012028534.1 | 8-oxo-dGTP diphosphatase | - |
| ZY05719_RS09485 (ZY05719_09530) | - | 1914821..1915150 (-) | 330 | WP_012775364.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| ZY05719_RS09490 (ZY05719_09535) | - | 1915140..1915427 (-) | 288 | WP_012028535.1 | hypothetical protein | - |
| ZY05719_RS09495 (ZY05719_09540) | - | 1915525..1915893 (-) | 369 | WP_012775365.1 | hypothetical protein | - |
| ZY05719_RS09500 (ZY05719_09545) | rnmV | 1915886..1916455 (-) | 570 | WP_012775366.1 | ribonuclease M5 | - |
| ZY05719_RS09505 (ZY05719_09550) | - | 1916439..1917221 (-) | 783 | WP_012028536.1 | TatD family hydrolase | - |
Sequence
Protein
Download Length: 817 a.a. Molecular weight: 90132.53 Da Isoelectric Point: 6.3138
>NTDB_id=119985 ZY05719_RS09315 WP_012027858.1 1877892..1880345(-) (clpC) [Streptococcus suis strain ZY05719 isolate diseased pig]
MKISRGLQGVYEDAQLIAQRYSSDYLETWHLLLAFVINPDTVAGAILAEYPADVLDYERAVYMVMGRRYHEELESFFFLP
SSKRVKELQVFAEKIAEIVKSKGLGTEHIFMGMLLDKRSTASQILDQVGFHFEDSDDKVRFLDLRKNLEAKAGFTKEHLK
AIRTMTKGGKPKQATVGNMMGMTQSQSGGLEDYTRDLTALARSGQLEPVIGRDEEISRMLQILSRKTKNNPVLVGDAGVG
KTALALGLAQRIANGEVPASLVNMRILELDLMNVIAGTRFRGDFEERMNNIINDIEEDGRVILFIDELHTIMGSGSGIDS
ILDAANILKPALSRGTLRTVGATTQDEYQKHIEKDAALVRRFAKVTIEEPSVADSVAILQGLKPAYEAHHKVTISDQAVV
TAVAYAKRYLTSKNLPDSAIDLLDEASATVQNRAKGQVEEGGLTALDQALMAGKYKTVTQLLLKAQEAENQATSYSLEVT
EEDILATLSRLSGIPVTKLSQTDAKKYLNLEQELHKRVIGQEEAISAVSRAIRRNQSGIRTGHRPIGSFMFLGPTGVGKT
ELAKALAEILFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGVLTDRKGRKVDFSNTVIIMTSNLGATALRDDKTVGFGALDLSKSQEHVEKRIFEALKKAYRPEFINRIDEKVVFH
SLTEADMQDVVKVMVKPLIAVAASKGITLKLQASALKLLAKEGYDPEMGARPLRRLLQTKLEDPLAEMLLRGELPAGVTL
KVGVKAEQLKFDSVKAG
MKISRGLQGVYEDAQLIAQRYSSDYLETWHLLLAFVINPDTVAGAILAEYPADVLDYERAVYMVMGRRYHEELESFFFLP
SSKRVKELQVFAEKIAEIVKSKGLGTEHIFMGMLLDKRSTASQILDQVGFHFEDSDDKVRFLDLRKNLEAKAGFTKEHLK
AIRTMTKGGKPKQATVGNMMGMTQSQSGGLEDYTRDLTALARSGQLEPVIGRDEEISRMLQILSRKTKNNPVLVGDAGVG
KTALALGLAQRIANGEVPASLVNMRILELDLMNVIAGTRFRGDFEERMNNIINDIEEDGRVILFIDELHTIMGSGSGIDS
ILDAANILKPALSRGTLRTVGATTQDEYQKHIEKDAALVRRFAKVTIEEPSVADSVAILQGLKPAYEAHHKVTISDQAVV
TAVAYAKRYLTSKNLPDSAIDLLDEASATVQNRAKGQVEEGGLTALDQALMAGKYKTVTQLLLKAQEAENQATSYSLEVT
EEDILATLSRLSGIPVTKLSQTDAKKYLNLEQELHKRVIGQEEAISAVSRAIRRNQSGIRTGHRPIGSFMFLGPTGVGKT
ELAKALAEILFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGVLTDRKGRKVDFSNTVIIMTSNLGATALRDDKTVGFGALDLSKSQEHVEKRIFEALKKAYRPEFINRIDEKVVFH
SLTEADMQDVVKVMVKPLIAVAASKGITLKLQASALKLLAKEGYDPEMGARPLRRLLQTKLEDPLAEMLLRGELPAGVTL
KVGVKAEQLKFDSVKAG
Nucleotide
Download Length: 2454 bp
>NTDB_id=119985 ZY05719_RS09315 WP_012027858.1 1877892..1880345(-) (clpC) [Streptococcus suis strain ZY05719 isolate diseased pig]
ATGAAGATTTCAAGAGGGTTACAGGGTGTCTATGAAGATGCTCAATTGATTGCACAGCGTTATAGTAGTGACTATTTGGA
GACCTGGCACTTGTTGTTAGCCTTTGTCATCAATCCAGATACCGTTGCGGGAGCTATTTTAGCAGAATATCCTGCGGATG
TATTGGACTATGAACGTGCAGTTTATATGGTGATGGGGCGGCGTTACCATGAAGAGTTAGAGAGCTTTTTCTTTCTTCCA
TCGTCCAAGCGGGTGAAGGAATTGCAGGTCTTTGCCGAGAAGATTGCGGAGATTGTCAAGAGTAAGGGGCTAGGAACGGA
GCATATTTTCATGGGAATGCTCTTGGACAAGCGTTCGACTGCCTCACAAATTCTGGATCAGGTCGGTTTTCACTTTGAGG
ATTCGGATGATAAGGTTCGTTTTCTGGATTTGCGGAAAAATCTGGAAGCCAAGGCTGGCTTTACCAAGGAGCATCTGAAG
GCTATCCGCACCATGACGAAAGGTGGCAAGCCCAAGCAGGCAACGGTTGGCAATATGATGGGCATGACCCAGTCACAAAG
TGGTGGCTTGGAAGACTATACACGTGATTTGACGGCTTTGGCCCGCTCAGGTCAGTTGGAGCCAGTCATCGGACGGGATG
AGGAAATTTCCCGTATGCTTCAGATTTTGTCGCGGAAAACCAAGAACAATCCTGTCTTGGTTGGAGATGCGGGTGTTGGG
AAAACAGCTCTGGCACTGGGTCTAGCCCAGCGGATTGCTAATGGAGAGGTGCCAGCTAGTCTTGTCAATATGCGGATCTT
GGAATTGGACTTGATGAATGTCATTGCGGGAACGCGTTTCCGTGGGGATTTTGAGGAGCGGATGAACAATATCATCAACG
ATATTGAAGAAGATGGTCGAGTGATTCTCTTCATTGATGAACTCCATACCATTATGGGATCGGGGTCAGGGATTGACTCG
ATCCTGGATGCTGCCAATATTTTGAAGCCTGCTCTGTCCCGTGGGACTTTGCGGACAGTTGGAGCAACGACTCAGGATGA
ATACCAGAAGCATATTGAAAAAGATGCTGCCTTAGTACGTCGATTTGCCAAGGTGACCATTGAGGAACCGAGTGTAGCAG
ACAGCGTAGCAATTTTGCAGGGGTTGAAGCCAGCCTATGAGGCTCACCACAAGGTGACCATTTCGGATCAGGCGGTGGTA
ACGGCGGTAGCCTATGCCAAACGCTATCTGACCAGTAAGAATTTGCCAGATTCGGCTATTGATTTGCTGGATGAAGCCAG
TGCGACGGTTCAAAATCGTGCCAAGGGACAGGTAGAAGAAGGTGGATTGACCGCTTTAGACCAAGCCTTGATGGCTGGGA
AATACAAGACGGTAACGCAGCTCTTGCTTAAGGCTCAAGAGGCGGAAAATCAGGCGACTAGCTATAGCTTGGAAGTCACA
GAAGAAGACATTTTGGCAACCCTCAGTCGCTTGTCAGGTATTCCTGTCACCAAACTGAGTCAGACAGATGCCAAGAAGTA
CCTTAATCTTGAACAGGAATTGCACAAGCGTGTTATCGGGCAGGAAGAGGCGATTTCAGCTGTCAGCCGGGCAATTCGCC
GCAACCAGTCAGGCATTCGCACTGGTCACAGACCGATTGGTTCCTTTATGTTCTTGGGGCCAACAGGTGTCGGTAAGACA
GAATTGGCCAAGGCCTTGGCGGAGATCCTCTTTGATGACGAATCTGCCTTGATTCGTTTTGATATGAGTGAGTATATGGA
GAAATTTGCGGCTAGTCGCCTCAACGGTGCTCCTCCAGGCTATGTTGGCTATGAAGAAGGGGGCGAGCTGACAGAAAAAG
TTCGCAACAAGCCATACTCTGTCCTACTTTTTGATGAGGTGGAGAAAGCACATCCAGATATTTTCAATGTTCTTTTGCAG
GTCTTGGATGACGGTGTCTTGACGGACAGAAAAGGTCGCAAGGTTGATTTCTCTAATACGGTCATCATTATGACGTCTAA
CTTAGGGGCAACCGCTTTACGTGATGATAAGACAGTTGGGTTTGGGGCTCTTGATTTGTCTAAGAGTCAGGAACACGTTG
AAAAACGGATTTTTGAGGCGTTGAAGAAGGCCTATCGTCCTGAATTTATTAACCGGATTGATGAAAAAGTGGTCTTCCAT
AGCCTGACAGAAGCAGATATGCAGGATGTGGTCAAGGTCATGGTCAAACCATTGATTGCCGTGGCGGCCAGCAAGGGTAT
TACCCTCAAATTGCAGGCTTCTGCTCTTAAACTCTTGGCCAAAGAAGGCTACGATCCAGAAATGGGTGCCCGCCCACTTC
GTCGCCTCCTCCAAACCAAGTTGGAAGATCCATTGGCAGAAATGCTCTTACGTGGAGAACTGCCAGCTGGTGTGACCTTA
AAAGTAGGGGTCAAGGCCGAGCAGTTGAAGTTTGATAGTGTGAAAGCAGGTTAG
ATGAAGATTTCAAGAGGGTTACAGGGTGTCTATGAAGATGCTCAATTGATTGCACAGCGTTATAGTAGTGACTATTTGGA
GACCTGGCACTTGTTGTTAGCCTTTGTCATCAATCCAGATACCGTTGCGGGAGCTATTTTAGCAGAATATCCTGCGGATG
TATTGGACTATGAACGTGCAGTTTATATGGTGATGGGGCGGCGTTACCATGAAGAGTTAGAGAGCTTTTTCTTTCTTCCA
TCGTCCAAGCGGGTGAAGGAATTGCAGGTCTTTGCCGAGAAGATTGCGGAGATTGTCAAGAGTAAGGGGCTAGGAACGGA
GCATATTTTCATGGGAATGCTCTTGGACAAGCGTTCGACTGCCTCACAAATTCTGGATCAGGTCGGTTTTCACTTTGAGG
ATTCGGATGATAAGGTTCGTTTTCTGGATTTGCGGAAAAATCTGGAAGCCAAGGCTGGCTTTACCAAGGAGCATCTGAAG
GCTATCCGCACCATGACGAAAGGTGGCAAGCCCAAGCAGGCAACGGTTGGCAATATGATGGGCATGACCCAGTCACAAAG
TGGTGGCTTGGAAGACTATACACGTGATTTGACGGCTTTGGCCCGCTCAGGTCAGTTGGAGCCAGTCATCGGACGGGATG
AGGAAATTTCCCGTATGCTTCAGATTTTGTCGCGGAAAACCAAGAACAATCCTGTCTTGGTTGGAGATGCGGGTGTTGGG
AAAACAGCTCTGGCACTGGGTCTAGCCCAGCGGATTGCTAATGGAGAGGTGCCAGCTAGTCTTGTCAATATGCGGATCTT
GGAATTGGACTTGATGAATGTCATTGCGGGAACGCGTTTCCGTGGGGATTTTGAGGAGCGGATGAACAATATCATCAACG
ATATTGAAGAAGATGGTCGAGTGATTCTCTTCATTGATGAACTCCATACCATTATGGGATCGGGGTCAGGGATTGACTCG
ATCCTGGATGCTGCCAATATTTTGAAGCCTGCTCTGTCCCGTGGGACTTTGCGGACAGTTGGAGCAACGACTCAGGATGA
ATACCAGAAGCATATTGAAAAAGATGCTGCCTTAGTACGTCGATTTGCCAAGGTGACCATTGAGGAACCGAGTGTAGCAG
ACAGCGTAGCAATTTTGCAGGGGTTGAAGCCAGCCTATGAGGCTCACCACAAGGTGACCATTTCGGATCAGGCGGTGGTA
ACGGCGGTAGCCTATGCCAAACGCTATCTGACCAGTAAGAATTTGCCAGATTCGGCTATTGATTTGCTGGATGAAGCCAG
TGCGACGGTTCAAAATCGTGCCAAGGGACAGGTAGAAGAAGGTGGATTGACCGCTTTAGACCAAGCCTTGATGGCTGGGA
AATACAAGACGGTAACGCAGCTCTTGCTTAAGGCTCAAGAGGCGGAAAATCAGGCGACTAGCTATAGCTTGGAAGTCACA
GAAGAAGACATTTTGGCAACCCTCAGTCGCTTGTCAGGTATTCCTGTCACCAAACTGAGTCAGACAGATGCCAAGAAGTA
CCTTAATCTTGAACAGGAATTGCACAAGCGTGTTATCGGGCAGGAAGAGGCGATTTCAGCTGTCAGCCGGGCAATTCGCC
GCAACCAGTCAGGCATTCGCACTGGTCACAGACCGATTGGTTCCTTTATGTTCTTGGGGCCAACAGGTGTCGGTAAGACA
GAATTGGCCAAGGCCTTGGCGGAGATCCTCTTTGATGACGAATCTGCCTTGATTCGTTTTGATATGAGTGAGTATATGGA
GAAATTTGCGGCTAGTCGCCTCAACGGTGCTCCTCCAGGCTATGTTGGCTATGAAGAAGGGGGCGAGCTGACAGAAAAAG
TTCGCAACAAGCCATACTCTGTCCTACTTTTTGATGAGGTGGAGAAAGCACATCCAGATATTTTCAATGTTCTTTTGCAG
GTCTTGGATGACGGTGTCTTGACGGACAGAAAAGGTCGCAAGGTTGATTTCTCTAATACGGTCATCATTATGACGTCTAA
CTTAGGGGCAACCGCTTTACGTGATGATAAGACAGTTGGGTTTGGGGCTCTTGATTTGTCTAAGAGTCAGGAACACGTTG
AAAAACGGATTTTTGAGGCGTTGAAGAAGGCCTATCGTCCTGAATTTATTAACCGGATTGATGAAAAAGTGGTCTTCCAT
AGCCTGACAGAAGCAGATATGCAGGATGTGGTCAAGGTCATGGTCAAACCATTGATTGCCGTGGCGGCCAGCAAGGGTAT
TACCCTCAAATTGCAGGCTTCTGCTCTTAAACTCTTGGCCAAAGAAGGCTACGATCCAGAAATGGGTGCCCGCCCACTTC
GTCGCCTCCTCCAAACCAAGTTGGAAGATCCATTGGCAGAAATGCTCTTACGTGGAGAACTGCCAGCTGGTGTGACCTTA
AAAGTAGGGGTCAAGGCCGAGCAGTTGAAGTTTGATAGTGTGAAAGCAGGTTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpC | Streptococcus pneumoniae TIGR4 |
71.464 |
99.51 |
0.711 |
| clpC | Streptococcus pneumoniae Rx1 |
71.464 |
99.51 |
0.711 |
| clpC | Streptococcus pneumoniae D39 |
71.464 |
99.51 |
0.711 |
| clpC | Streptococcus mutans UA159 |
66.173 |
99.143 |
0.656 |
| clpC | Streptococcus thermophilus LMG 18311 |
64.828 |
99.878 |
0.647 |
| clpC | Streptococcus thermophilus LMD-9 |
64.706 |
99.878 |
0.646 |
| clpC | Lactococcus lactis subsp. lactis strain DGCC12653 |
48.086 |
100 |
0.492 |
| clpC | Bacillus subtilis subsp. subtilis str. 168 |
44.403 |
99.51 |
0.442 |