Detailed information NTG0119978

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: ZY05719_RS07945
• Genome accession: NZ_CP007497
• Coordinates: 1594356..1595405 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis strain ZY05719 isolate diseased pig
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1589356..1600405

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ZY05719_RS07925 (ZY05719_07970)	nadE	1589762..1590586 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
ZY05719_RS07930 (ZY05719_07975)	-	1591882..1592409 (-)	528	WP_012027591.1	VanZ family protein	-
ZY05719_RS07935 (ZY05719_07980)	rlmN	1592406..1593518 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
ZY05719_RS07940 (ZY05719_07985)	-	1593527..1594168 (-)	642	WP_012027595.1	YutD family protein	-
ZY05719_RS07945 (ZY05719_07990)	sepM	1594356..1595405 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
ZY05719_RS07950 (ZY05719_07995)	coaD	1595392..1595880 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
ZY05719_RS07955 (ZY05719_08000)	rsmD	1595870..1596409 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
ZY05719_RS07960 (ZY05719_08005)	-	1596717..1597439 (-)	723	WP_012027598.1	lipoprotein	-
ZY05719_RS07965 (ZY05719_08010)	-	1597496..1597882 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
ZY05719_RS07970 (ZY05719_08015)	-	1597882..1598100 (-)	219	WP_004194736.1	YqgQ family protein	-
ZY05719_RS07975 (ZY05719_08020)	-	1598408..1599010 (-)	603	WP_012027601.1	response regulator transcription factor	-
ZY05719_RS07980 (ZY05719_08025)	-	1599007..1600101 (-)	1095	WP_012027602.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=119978 ZY05719_RS07945 WP_012775295.1 1594356..1595405(-) (sepM) [Streptococcus suis strain ZY05719 isolate diseased pig]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=119978 ZY05719_RS07945 WP_012775295.1 1594356..1595405(-) (sepM) [Streptococcus suis strain ZY05719 isolate diseased pig]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605