Detailed information    

insolico Bioinformatically predicted

Overview

Name   rec2   Type   Machinery gene
Locus tag   NTHI723_RS08240 Genome accession   NZ_CP007472
Coordinates   1662804..1665170 (+) Length   788 a.a.
NCBI ID   WP_011271804.1    Uniprot ID   Q4QPI3
Organism   Haemophilus influenzae strain 723     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1657804..1670170
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NTHI723_RS08215 (NTHI723_01649) - 1658153..1659451 (-) 1299 WP_044364986.1 N-acetylmuramoyl-L-alanine amidase -
  NTHI723_RS08220 (NTHI723_01650) tsaE 1659459..1659935 (-) 477 WP_005693857.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  NTHI723_RS08225 (NTHI723_01651) folK 1660011..1660493 (-) 483 WP_011271807.1 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase -
  NTHI723_RS08230 (NTHI723_01652) pcnB 1660502..1661860 (-) 1359 WP_044365154.1 polynucleotide adenylyltransferase PcnB -
  NTHI723_RS08235 (NTHI723_01653) dksA 1662108..1662545 (-) 438 WP_011271805.1 RNA polymerase-binding protein DksA -
  NTHI723_RS08240 (NTHI723_01654) rec2 1662804..1665170 (+) 2367 WP_011271804.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  NTHI723_RS08245 (NTHI723_01655) msbA 1665211..1666974 (+) 1764 WP_011271803.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  NTHI723_RS08250 (NTHI723_01656) lpxK 1667047..1668045 (+) 999 WP_011271802.1 tetraacyldisaccharide 4'-kinase -
  NTHI723_RS08255 (NTHI723_01657) kdsB 1668116..1668880 (+) 765 WP_005663240.1 3-deoxy-manno-octulosonate cytidylyltransferase -

Sequence

Protein


Download         Length: 788 a.a.        Molecular weight: 89303.80 Da        Isoelectric Point: 9.9049

>NTDB_id=119788 NTHI723_RS08240 WP_011271804.1 1662804..1665170(+) (rec2) [Haemophilus influenzae strain 723]
MKLNLITLAVLLIVADLTLLFLPQPLLLPWQVALVIALVLIFLFIFLRRNFLVSLAFFVASLGYFHYSALSLSQQAQNIT
AQNQVVTFKIQEILHQQDYQTLIATATLENNLQEQRIFLNWKAKEVPQLSEIWQAEISLRPLSARLNFGGFDRQQWYFSK
GITAVGTVKSAVKIADVSSLRAEKLQQVKKQTEGLSLQGLLIALAFGERAWLDKTTWSIYQQTNTAHLIAISGLHIGLAM
GIGFCLARVVQVFCPTRFIHPYFPLVFGVLFALIYAYLAGFSVPTFRAISALVFVLFIQIMRRHYSPIQLFTLVVGFLLF
CDPLMPLSVSFWLSCGAVGCLLLWYRYVPFSLFQWKNRPFSPKVRWIFSLFHLQFGLLLFFTPLQLFLFNGLSLSGFLAN
LMAVPIYSFLLVPLILFAVFTNGTMFSWQLANKLAEGITGLISVFQGNWFNVSFNLALVLTALCAGIFMLIIWSIYREPE
VSSSTWKIKRPRFFTLNLSKPLLKTDRINVLRCSFGIILMCFMILLFKQLSKPTWQVDTLDVGQGLATLIVKNGKGILYD
TGSSWRGGSMAELEILPYLQREGIVLEKLILSHDDNDHAGGASTILKAYPNVELITPSRKNYGENYRTFCTAGRDWHWQG
LHFQILSPHNVATRADNPHSCVILVDDGKNSVLLTGDAEAKNEQIFARTLGKIDVLQVGHHGSKTSTSEYLLSQVRPDVA
IISSGRWNPWKFPHYSVMERLHRYKSAVENTAVSGQVRVNFFQDRLEIQQARTKFSPWYARVIGLSKE

Nucleotide


Download         Length: 2367 bp        

>NTDB_id=119788 NTHI723_RS08240 WP_011271804.1 1662804..1665170(+) (rec2) [Haemophilus influenzae strain 723]
ATGAAATTAAACTTAATAACTTTAGCTGTCTTGTTAATTGTCGCGGATTTAACGTTGTTATTTCTACCGCAACCGTTGCT
ATTGCCTTGGCAAGTTGCTCTCGTTATTGCGCTTGTTTTGATTTTTCTTTTTATTTTCTTGCGTAGAAATTTCTTAGTTA
GCCTTGCTTTTTTTGTTGCCTCTCTTGGCTATTTTCATTATTCGGCTTTGAGTTTATCACAACAAGCTCAAAATATTACC
GCTCAAAATCAAGTGGTAACTTTTAAGATTCAAGAAATTTTGCACCAACAGGATTATCAAACGCTTATCGCCACAGCAAC
ATTGGAGAATAATTTGCAAGAACAACGAATTTTCTTAAATTGGAAAGCGAAAGAGGTGCCTCAATTATCGGAAATTTGGC
AAGCTGAAATTTCTTTACGTCCCCTTTCTGCGCGATTAAATTTTGGTGGGTTTGATCGGCAACAATGGTATTTTTCAAAA
GGAATTACGGCTGTTGGAACGGTAAAAAGTGCGGTGAAAATTGCGGATGTTTCATCATTGCGTGCAGAAAAATTGCAACA
AGTAAAAAAACAAACAGAAGGGTTGTCCTTACAAGGTTTATTGATTGCCTTAGCTTTTGGCGAACGGGCTTGGTTAGATA
AAACCACTTGGTCAATTTACCAACAAACCAATACTGCGCATCTTATTGCTATTTCTGGCTTACATATTGGGTTGGCTATG
GGAATTGGATTTTGCTTGGCGCGTGTTGTGCAAGTCTTTTGCCCCACCCGTTTTATTCATCCTTATTTTCCTTTAGTTTT
TGGTGTTTTATTTGCTTTAATTTATGCGTATTTGGCTGGTTTTAGTGTGCCAACTTTTCGTGCCATTTCAGCACTTGTTT
TCGTTTTATTTATTCAAATAATGAGGCGACATTATTCGCCCATTCAGCTTTTTACGTTGGTTGTCGGATTCTTGCTTTTC
TGCGATCCATTAATGCCGCTTTCGGTCAGTTTTTGGCTTTCTTGTGGAGCGGTTGGGTGTTTGCTCCTCTGGTATCGTTA
TGTGCCTTTTTCACTTTTTCAATGGAAAAATCGCCCTTTTTCTCCAAAAGTGCGGTGGATTTTTAGTTTATTTCATTTGC
AATTTGGGTTATTGCTCTTTTTTACGCCTTTGCAACTTTTTCTATTTAATGGCTTATCGTTAAGTGGATTTTTAGCCAAT
CTTATGGCGGTTCCAATTTATAGTTTTTTGCTTGTGCCATTAATTTTATTTGCCGTTTTTACTAACGGCACAATGTTTTC
TTGGCAACTAGCAAACAAGTTAGCCGAAGGAATTACTGGGTTAATTTCTGTTTTCCAAGGGAATTGGTTTAATGTTTCAT
TTAATTTAGCATTGGTTTTAACCGCACTTTGTGCAGGAATTTTTATGTTAATTATTTGGAGTATTTATCGAGAACCAGAG
GTTTCATCATCAACTTGGAAAATTAAACGACCAAGATTTTTTACATTGAATCTCAGTAAACCTTTGCTAAAAACTGATCG
AATCAACGTTTTGCGATGTTCTTTCGGCATTATTCTTATGTGTTTTATGATTTTGTTGTTTAAACAATTGAGCAAGCCAA
CTTGGCAGGTAGATACTTTAGATGTGGGGCAGGGCTTGGCAACGCTGATTGTGAAAAATGGCAAAGGGATTCTTTATGAT
ACGGGTTCTTCTTGGCGAGGTGGAAGTATGGCTGAGTTGGAAATTTTGCCTTATTTACAAAGAGAAGGGATTGTTTTGGA
AAAATTGATTTTAAGCCACGACGATAACGATCACGCAGGTGGTGCTTCGACAATTTTAAAGGCGTATCCCAATGTGGAAT
TGATTACCCCTTCACGGAAAAACTATGGGGAAAATTACCGCACTTTTTGTACTGCTGGGCGTGATTGGCATTGGCAAGGG
TTGCATTTTCAAATACTTTCTCCTCACAACGTTGCGACACGAGCTGATAATCCCCATTCTTGTGTGATTTTAGTCGATGA
TGGAAAGAATAGCGTTTTGCTAACTGGCGATGCTGAAGCAAAAAATGAGCAAATTTTTGCCCGCACTTTAGGCAAAATCG
ATGTGTTGCAAGTGGGGCATCATGGGAGTAAAACATCGACAAGTGAATACTTGCTTTCTCAGGTTAGACCAGATGTAGCG
ATTATTTCTAGTGGGCGTTGGAATCCGTGGAAATTCCCTCATTATTCGGTTATGGAAAGGCTTCATCGCTATAAAAGTGC
GGTAGAAAATACCGCTGTTTCGGGGCAAGTGCGGGTAAATTTTTTTCAAGACCGATTAGAAATCCAGCAAGCTCGCACAA
AATTTTCCCCTTGGTATGCGCGTGTAATTGGATTATCAAAGGAATAA

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(28-171)

Competence protein (Competence)

(204-473)

Metallo-beta-lactamase superfamily (Lactamase_B)

(541-725)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QPI3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rec2 Haemophilus influenzae Rd KW20

97.335

100

0.973

Multiple sequence alignment