Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   A421_RS11370 Genome accession   NZ_CP007462
Coordinates   2274764..2276569 (-) Length   601 a.a.
NCBI ID   WP_003724606.1    Uniprot ID   A0A3D7VFE2
Organism   Listeria monocytogenes serotype 4b str. 02-6680     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 2269764..2281569
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A421_RS11350 (A421_2244) isdE 2270687..2271559 (-) 873 WP_003727849.1 heme ABC transporter substrate-binding protein IsdE -
  A421_RS11355 (A421_2245) hbp2 2271646..2273355 (-) 1710 WP_003727848.1 hemin/hemoglobin-binding protein Hbp2 -
  A421_RS11360 (A421_2246) isdC 2273368..2273994 (-) 627 WP_003724604.1 heme uptake protein IsdC -
  A421_RS11365 (A421_2247) - 2274205..2274465 (-) 261 WP_003724605.1 DUF3116 family protein -
  A421_RS11370 (A421_2248) pepF 2274764..2276569 (-) 1806 WP_003724606.1 oligoendopeptidase F Regulator
  A421_RS11375 (A421_2249) - 2276644..2277759 (-) 1116 WP_003740782.1 competence protein CoiA -
  A421_RS11380 (A421_2250) mecA 2277885..2278538 (-) 654 WP_003724608.1 adaptor protein MecA -
  A421_RS11385 (A421_2251) spxA 2278770..2279165 (-) 396 WP_003720569.1 transcriptional regulator SpxA -
  A421_RS11390 (A421_2252) - 2279485..2280453 (-) 969 WP_003722315.1 ABC transporter ATP-binding protein -
  A421_RS11395 (A421_2253) - 2280450..2281526 (-) 1077 WP_003722316.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 601 a.a.        Molecular weight: 68550.63 Da        Isoelectric Point: 4.5488

>NTDB_id=119675 A421_RS11370 WP_003724606.1 2274764..2276569(-) (pepF) [Listeria monocytogenes serotype 4b str. 02-6680]
MSKTNALPLREEVPENLTWDLTTIYPNDEAWEQAFTDLQKITEESEQFKGRLSESSQTLYEALQFRDNAYDLISNLYVYA
HLKMDQDTANAKYQGLHSRAGSLVTKLMSALSYYDPEILAMDESVLKQFLNENKDLQLYAHLLEELNLSRPYILSEKEEA
LLANAGEVLGSSSNTFNTLNNADMKFPTIKDENGEDIEITHGRFGKLLESNDPRVRREAFLGVYSVYEGLKNTLASTLNG
QVKKSNFYASTRGYTSAREAALSGNHIPETVYDSLLKSVNANADLLHRYVKLRKELLGLEELHMYDLYTPLSDDVNLEFT
YEEAKELVLEALKPLGDEYQAILKEAFDSRWIDVMENKGKRSGAYSSGSYSTSPYILLNWQDNINNVYTLAHELGHSVHS
YYTRKNQPFVYGDYSIFLAEVASTTNENLLTDYLLKKYDDPKVRAYLLNHYLDGFKGTVFRQTQFAEFEHAIHQADQEGV
ALTADYLTETYFDINKKYYGEAMVYDAEIGYEWSRIPHFYMNYYVFQYATGFSAASALSAKILTEGQEAVTAYIDFLKAG
SSDYPIDVLKKAGVDMATPNPVDDALKVFEQRLDELEKLVK

Nucleotide


Download         Length: 1806 bp        

>NTDB_id=119675 A421_RS11370 WP_003724606.1 2274764..2276569(-) (pepF) [Listeria monocytogenes serotype 4b str. 02-6680]
TTGAGTAAAACAAATGCATTACCTTTAAGAGAAGAAGTACCGGAAAATCTAACTTGGGATTTAACTACGATTTATCCAAA
CGATGAAGCTTGGGAACAAGCATTTACAGATTTGCAAAAAATCACAGAAGAAAGCGAGCAATTTAAAGGGCGTTTATCGG
AAAGCAGCCAGACACTATATGAAGCACTTCAATTTCGAGATAATGCATATGATTTAATTAGTAACTTATATGTATATGCG
CATTTGAAAATGGACCAAGATACGGCTAATGCGAAATATCAAGGTTTACATAGTCGCGCAGGAAGCCTAGTTACAAAGCT
AATGTCTGCACTGTCTTATTATGATCCTGAAATTTTAGCTATGGACGAAAGCGTTTTAAAACAATTTTTAAATGAGAACA
AAGATTTACAATTATATGCGCATTTACTAGAAGAGTTAAATTTAAGCCGACCGTATATTTTAAGTGAGAAAGAGGAGGCT
TTACTAGCTAACGCAGGTGAAGTGCTTGGCAGTTCGTCTAATACTTTTAATACCTTGAATAATGCAGATATGAAGTTTCC
AACCATTAAAGATGAGAACGGGGAAGATATCGAAATTACTCATGGTCGTTTCGGGAAATTGTTGGAAAGTAATGATCCGC
GAGTTCGTCGTGAAGCGTTTCTTGGTGTGTATTCTGTTTATGAAGGCCTAAAAAACACCTTAGCCTCTACTTTGAATGGA
CAAGTGAAGAAGTCTAATTTTTATGCTTCCACTCGTGGCTACACGTCAGCTCGTGAAGCGGCTCTTTCTGGGAACCATAT
TCCTGAAACAGTATATGATTCCTTGTTAAAATCAGTAAATGCGAATGCAGATTTGCTTCATCGTTATGTGAAGTTACGTA
AAGAATTACTTGGCTTAGAGGAATTGCATATGTATGATCTTTATACGCCACTTTCTGATGATGTTAATTTGGAGTTTACT
TATGAAGAAGCGAAAGAACTTGTGCTTGAAGCGCTTAAACCGCTTGGTGATGAATATCAAGCAATTTTAAAAGAAGCATT
TGATAGTCGTTGGATTGATGTGATGGAAAATAAAGGAAAACGTAGTGGAGCCTATTCTTCTGGTTCGTATAGTACGAGTC
CTTATATTTTACTCAATTGGCAGGATAATATTAACAATGTTTACACACTTGCGCATGAATTAGGGCATAGTGTGCATAGT
TATTATACAAGAAAAAACCAACCATTTGTTTATGGTGATTATTCGATTTTCTTAGCGGAGGTTGCTTCGACAACAAATGA
AAATTTACTAACTGATTATCTTCTTAAGAAATATGATGATCCAAAAGTTCGTGCTTACTTGTTGAATCACTATTTGGATG
GATTCAAGGGTACTGTATTCCGTCAAACCCAATTTGCTGAATTTGAACATGCTATTCATCAAGCGGATCAAGAAGGAGTG
GCGCTGACTGCGGATTACTTGACCGAAACATATTTTGATATTAACAAGAAATATTACGGGGAAGCGATGGTTTATGATGC
TGAAATCGGTTATGAATGGTCTCGTATTCCGCATTTTTATATGAATTATTATGTGTTCCAATATGCGACTGGTTTTTCTG
CAGCATCTGCATTGAGTGCGAAGATTTTAACAGAAGGCCAAGAAGCGGTGACTGCCTATATTGATTTCTTGAAAGCGGGA
AGTTCGGATTATCCTATCGATGTGTTGAAAAAAGCAGGAGTTGATATGGCAACTCCTAATCCGGTGGATGATGCACTAAA
AGTATTTGAACAAAGATTAGATGAACTAGAAAAATTAGTTAAATAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(207-586)

Oligopeptidase F (Peptidase_M3_N)

(117-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3D7VFE2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

51.014

98.502

0.503

Multiple sequence alignment