Detailed information
Bioinformatically predicted
Overview
| Name | pepF | Type | Regulator |
| Locus tag | STAB1101_RS05230 | Genome accession | NZ_CP007240 |
| Coordinates | 1049369..1051174 (-) | Length | 601 a.a. |
| NCBI ID | WP_038431433.1 | Uniprot ID | - |
| Organism | Streptococcus pyogenes strain 7F7 | ||
| Function | degradation of XIP; competence shut-off (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1029119..1076167 | 1049369..1051174 | within | 0 |
Gene organization within MGE regions
Location: 1029119..1076167
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| STAB1101_RS05135 (STAB1101_05135) | - | 1029157..1030431 (-) | 1275 | WP_020837316.1 | polysaccharide deacetylase family protein | - |
| STAB1101_RS05140 (STAB1101_05140) | - | 1030526..1031953 (-) | 1428 | WP_011284931.1 | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | - |
| STAB1101_RS05145 (STAB1101_05145) | ptsP | 1032138..1033871 (-) | 1734 | WP_020837320.1 | phosphoenolpyruvate--protein phosphotransferase | - |
| STAB1101_RS05150 (STAB1101_05150) | - | 1033876..1034139 (-) | 264 | WP_002984031.1 | phosphocarrier protein HPr | - |
| STAB1101_RS05155 (STAB1101_05155) | - | 1034532..1034750 (+) | 219 | WP_002989242.1 | redoxin NrdH | - |
| STAB1101_RS05160 (STAB1101_05160) | nrdE | 1034770..1036929 (+) | 2160 | WP_002993430.1 | class 1b ribonucleoside-diphosphate reductase subunit alpha | - |
| STAB1101_RS05165 (STAB1101_05165) | nrdF | 1037262..1038221 (+) | 960 | WP_002993434.1 | class 1b ribonucleoside-diphosphate reductase subunit beta | - |
| STAB1101_RS05170 (STAB1101_05170) | - | 1038283..1039509 (+) | 1227 | WP_002993437.1 | chloride channel protein | - |
| STAB1101_RS08765 | - | 1039605..1040762 (+) | 1158 | Protein_990 | IS3 family transposase | - |
| STAB1101_RS05190 (STAB1101_05190) | - | 1040854..1041549 (-) | 696 | WP_002995750.1 | CPBP family intramembrane glutamic endopeptidase | - |
| STAB1101_RS05195 (STAB1101_05195) | - | 1041568..1042328 (-) | 761 | Protein_992 | DUF3169 family protein | - |
| STAB1101_RS05200 (STAB1101_05200) | - | 1042325..1042540 (-) | 216 | WP_002989220.1 | helix-turn-helix transcriptional regulator | - |
| STAB1101_RS05210 (STAB1101_05210) | alaS | 1042901..1045519 (-) | 2619 | WP_038431432.1 | alanine--tRNA ligase | - |
| STAB1101_RS05215 (STAB1101_05215) | prsA | 1045906..1046961 (-) | 1056 | WP_011184661.1 | peptidylprolyl isomerase PrsA | - |
| STAB1101_RS05220 (STAB1101_05220) | - | 1047024..1047731 (-) | 708 | WP_011017939.1 | O-methyltransferase | - |
| STAB1101_RS05225 (STAB1101_05225) | - | 1047797..1048993 (-) | 1197 | WP_002995765.1 | OFA family MFS transporter | - |
| STAB1101_RS05230 (STAB1101_05230) | pepF | 1049369..1051174 (-) | 1806 | WP_038431433.1 | oligoendopeptidase F | Regulator |
| STAB1101_RS05235 (STAB1101_05235) | - | 1051187..1052149 (-) | 963 | WP_038431434.1 | competence protein CoiA | - |
| STAB1101_RS05240 (STAB1101_05240) | - | 1052444..1053160 (-) | 717 | WP_038431436.1 | pseudouridine synthase | - |
| STAB1101_RS05245 (STAB1101_05245) | nagB | 1053279..1053983 (-) | 705 | WP_002995779.1 | glucosamine-6-phosphate deaminase | - |
| STAB1101_RS05250 (STAB1101_05250) | queA | 1054185..1055213 (+) | 1029 | WP_002995782.1 | tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA | - |
| STAB1101_RS05255 (STAB1101_05255) | - | 1055220..1056440 (+) | 1221 | WP_038431438.1 | DUF3114 domain-containing protein | - |
| STAB1101_RS09115 (STAB1101_05260) | - | 1056554..1057227 (-) | 674 | Protein_1004 | serine hydrolase | - |
| STAB1101_RS09120 (STAB1101_05270) | - | 1057369..1057602 (-) | 234 | WP_002983979.1 | hypothetical protein | - |
| STAB1101_RS05275 (STAB1101_05275) | sodA | 1057769..1058374 (-) | 606 | WP_002983977.1 | superoxide dismutase SodA | - |
| STAB1101_RS05280 (STAB1101_05280) | holA | 1058471..1059511 (-) | 1041 | WP_011054659.1 | DNA polymerase III subunit delta | - |
| STAB1101_RS05285 (STAB1101_05285) | - | 1059582..1061825 (-) | 2244 | WP_002995623.1 | DNA internalization-related competence protein ComEC/Rec2 | - |
| STAB1101_RS05290 (STAB1101_05290) | - | 1061806..1062468 (-) | 663 | WP_002995626.1 | ComEA family DNA-binding protein | - |
| STAB1101_RS05295 (STAB1101_05295) | - | 1062668..1063408 (-) | 741 | WP_012560804.1 | lysophospholipid acyltransferase family protein | - |
| STAB1101_RS05300 (STAB1101_05300) | - | 1063526..1064302 (+) | 777 | WP_002994360.1 | tRNA1(Val) (adenine(37)-N6)-methyltransferase | - |
| STAB1101_RS05305 (STAB1101_05305) | - | 1064292..1064570 (+) | 279 | WP_002989164.1 | GIY-YIG nuclease family protein | - |
| STAB1101_RS05310 (STAB1101_05310) | - | 1064594..1066594 (-) | 2001 | WP_002994363.1 | potassium transporter Kup | - |
| STAB1101_RS05315 (STAB1101_05315) | - | 1066721..1068340 (-) | 1620 | WP_002989158.1 | DEAD/DEAH box helicase | - |
| STAB1101_RS05320 (STAB1101_05320) | - | 1068647..1070191 (-) | 1545 | WP_002989155.1 | peptide chain release factor 3 | - |
| STAB1101_RS05325 (STAB1101_05325) | - | 1070439..1071134 (-) | 696 | WP_002994365.1 | TIGR02206 family membrane protein | - |
| STAB1101_RS05330 (STAB1101_05330) | - | 1071238..1072605 (-) | 1368 | WP_002994368.1 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase | - |
| STAB1101_RS05335 (STAB1101_05335) | - | 1072804..1073850 (-) | 1047 | WP_002994369.1 | D-alanine--D-alanine ligase | - |
| STAB1101_RS05340 (STAB1101_05340) | recR | 1073951..1074547 (-) | 597 | WP_002983939.1 | recombination mediator RecR | - |
| STAB1101_RS09125 | - | 1074594..1074776 (-) | 183 | WP_011888786.1 | penicillin-binding protein | - |
| STAB1101_RS05345 (STAB1101_05345) | - | 1075336..1076115 (-) | 780 | WP_014635570.1 | formate/nitrite transporter family protein | - |
Sequence
Protein
Download Length: 601 a.a. Molecular weight: 69426.36 Da Isoelectric Point: 4.7090
>NTDB_id=118038 STAB1101_RS05230 WP_038431433.1 1049369..1051174(-) (pepF) [Streptococcus pyogenes strain 7F7]
MTDNRSHLEEKYTWDLSTIFATDKDWEAEVSDLATEIDAAKDFSGHLLDSSANLLTITDTYLELARRVEKVYVYAHMKND
QDTTVAKYQEYQAKASGLYAKFSEVFSFYDPEVMMLHQEDYQAFLTETPELKVYNHFFDKLFQAREHVLSQAEEELLAGA
QEIFNGAEETFSILDNADIVFPIVRNDKGENVELTHGNFISLMESKDRSVRQAAYEAMYSTYEQFQHTYAKTLQTNVKVQ
NYKARVHKYDSARQAAMAANFIPEAVYDTLLETVNKHLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALE
KAEKVLAVFGKDYADRVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSLHSTFTRET
QPYVYGDYSIFLAEIASTTNENIMTEALLNEVQDEKERFAILNHYLDGFRGTVFRQTQFAEFEHAIHQADQKGEVLTSEY
LNQLYADLNEKYYGLSKKDNHFIQYEWARIPHFYYNYYVYQYATGFAAASYLADKIVHGTQDDIDHYLAYLKSGNSDYPL
EVIAKAGVDMAKGDYLEAAFKVFDERLTELEVLVSKGIHKS
MTDNRSHLEEKYTWDLSTIFATDKDWEAEVSDLATEIDAAKDFSGHLLDSSANLLTITDTYLELARRVEKVYVYAHMKND
QDTTVAKYQEYQAKASGLYAKFSEVFSFYDPEVMMLHQEDYQAFLTETPELKVYNHFFDKLFQAREHVLSQAEEELLAGA
QEIFNGAEETFSILDNADIVFPIVRNDKGENVELTHGNFISLMESKDRSVRQAAYEAMYSTYEQFQHTYAKTLQTNVKVQ
NYKARVHKYDSARQAAMAANFIPEAVYDTLLETVNKHLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALE
KAEKVLAVFGKDYADRVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSLHSTFTRET
QPYVYGDYSIFLAEIASTTNENIMTEALLNEVQDEKERFAILNHYLDGFRGTVFRQTQFAEFEHAIHQADQKGEVLTSEY
LNQLYADLNEKYYGLSKKDNHFIQYEWARIPHFYYNYYVYQYATGFAAASYLADKIVHGTQDDIDHYLAYLKSGNSDYPL
EVIAKAGVDMAKGDYLEAAFKVFDERLTELEVLVSKGIHKS
Nucleotide
Download Length: 1806 bp
>NTDB_id=118038 STAB1101_RS05230 WP_038431433.1 1049369..1051174(-) (pepF) [Streptococcus pyogenes strain 7F7]
ATGACTGATAATCGCAGCCATTTAGAAGAAAAATACACTTGGGATTTGAGCACTATTTTTGCAACAGATAAGGATTGGGA
AGCTGAAGTCAGTGACTTAGCTACTGAAATTGACGCGGCTAAGGATTTTTCAGGTCATTTACTAGATTCTAGCGCTAATC
TGTTGACAATTACAGATACTTATTTAGAGTTAGCTCGTCGTGTTGAGAAAGTCTATGTTTATGCTCACATGAAAAATGAC
CAAGACACTACTGTTGCCAAGTATCAAGAATACCAAGCTAAGGCTTCAGGCTTGTATGCAAAGTTTAGCGAAGTCTTTTC
ATTCTATGATCCAGAAGTGATGATGCTTCATCAAGAAGACTATCAGGCTTTCCTTACTGAAACCCCTGAGTTGAAAGTGT
ACAACCATTTCTTTGACAAATTATTCCAAGCCCGCGAACATGTTCTTAGTCAAGCAGAAGAGGAATTATTAGCAGGAGCT
CAAGAAATTTTCAATGGTGCGGAAGAAACCTTTAGTATTCTTGATAACGCTGACATTGTTTTCCCGATAGTCAGAAATGA
TAAAGGTGAAAACGTTGAATTAACCCATGGTAACTTCATTAGCCTAATGGAATCTAAGGACCGTAGCGTTCGCCAAGCTG
CTTATGAAGCCATGTATAGTACTTATGAACAGTTCCAACATACTTACGCTAAAACCTTGCAAACCAATGTGAAAGTGCAA
AACTATAAGGCGCGTGTTCATAAATACGATTCAGCACGTCAAGCTGCCATGGCTGCTAACTTTATTCCAGAAGCTGTTTA
CGACACTTTATTAGAAACGGTTAACAAACATTTACCACTCTTACACCGTTATTTGAAATTGCGTCAAGAGGTTCTTGGTT
TAGACGATTTGAAGATGTATGATGTTTACACACCATTATCTGAAACAGATTTAGCCATTGGTTATGATGAGGCTTTGGAA
AAGGCTGAGAAGGTTTTGGCTGTTTTTGGTAAGGATTACGCAGATCGTGTACATCGTGCTTTTACCGAACGTTGGATTGA
TGTTCACGTCAATAAAGGGAAGCGCTCTGGGGCTTATTCAGGTGGTTCCTATGATACCAATGCCTTCATGCTGTTGAACT
GGCAAGATACACTTGATAATCTTTACACACTTGTCCACGAAACAGGCCACAGTTTGCATTCTACTTTCACTCGTGAAACA
CAGCCTTATGTGTATGGGGATTATAGTATCTTCTTGGCAGAAATTGCATCCACAACGAATGAAAACATCATGACAGAAGC
TCTCTTAAATGAAGTGCAAGATGAGAAAGAACGCTTTGCCATTTTAAACCATTACCTCGATGGTTTCCGTGGAACAGTTT
TCCGTCAAACCCAATTTGCTGAGTTTGAACATGCCATTCATCAAGCTGATCAAAAAGGAGAAGTGTTAACAAGTGAATAC
CTTAACCAGCTATACGCTGATTTAAATGAAAAATATTATGGTTTAAGTAAAAAAGATAATCATTTTATTCAGTATGAATG
GGCACGTATTCCTCATTTCTATTACAATTATTATGTTTACCAATATGCAACAGGGTTTGCAGCTGCAAGCTATTTAGCGG
ATAAGATTGTGCATGGCACACAAGATGATATCGATCATTACTTGGCCTACCTCAAGTCAGGAAATTCTGATTACCCACTT
GAAGTGATTGCTAAAGCAGGCGTTGATATGGCAAAAGGTGATTATTTGGAAGCTGCCTTTAAAGTCTTTGACGAACGTCT
AACAGAACTTGAAGTACTCGTGTCCAAAGGCATACACAAAAGCTAA
ATGACTGATAATCGCAGCCATTTAGAAGAAAAATACACTTGGGATTTGAGCACTATTTTTGCAACAGATAAGGATTGGGA
AGCTGAAGTCAGTGACTTAGCTACTGAAATTGACGCGGCTAAGGATTTTTCAGGTCATTTACTAGATTCTAGCGCTAATC
TGTTGACAATTACAGATACTTATTTAGAGTTAGCTCGTCGTGTTGAGAAAGTCTATGTTTATGCTCACATGAAAAATGAC
CAAGACACTACTGTTGCCAAGTATCAAGAATACCAAGCTAAGGCTTCAGGCTTGTATGCAAAGTTTAGCGAAGTCTTTTC
ATTCTATGATCCAGAAGTGATGATGCTTCATCAAGAAGACTATCAGGCTTTCCTTACTGAAACCCCTGAGTTGAAAGTGT
ACAACCATTTCTTTGACAAATTATTCCAAGCCCGCGAACATGTTCTTAGTCAAGCAGAAGAGGAATTATTAGCAGGAGCT
CAAGAAATTTTCAATGGTGCGGAAGAAACCTTTAGTATTCTTGATAACGCTGACATTGTTTTCCCGATAGTCAGAAATGA
TAAAGGTGAAAACGTTGAATTAACCCATGGTAACTTCATTAGCCTAATGGAATCTAAGGACCGTAGCGTTCGCCAAGCTG
CTTATGAAGCCATGTATAGTACTTATGAACAGTTCCAACATACTTACGCTAAAACCTTGCAAACCAATGTGAAAGTGCAA
AACTATAAGGCGCGTGTTCATAAATACGATTCAGCACGTCAAGCTGCCATGGCTGCTAACTTTATTCCAGAAGCTGTTTA
CGACACTTTATTAGAAACGGTTAACAAACATTTACCACTCTTACACCGTTATTTGAAATTGCGTCAAGAGGTTCTTGGTT
TAGACGATTTGAAGATGTATGATGTTTACACACCATTATCTGAAACAGATTTAGCCATTGGTTATGATGAGGCTTTGGAA
AAGGCTGAGAAGGTTTTGGCTGTTTTTGGTAAGGATTACGCAGATCGTGTACATCGTGCTTTTACCGAACGTTGGATTGA
TGTTCACGTCAATAAAGGGAAGCGCTCTGGGGCTTATTCAGGTGGTTCCTATGATACCAATGCCTTCATGCTGTTGAACT
GGCAAGATACACTTGATAATCTTTACACACTTGTCCACGAAACAGGCCACAGTTTGCATTCTACTTTCACTCGTGAAACA
CAGCCTTATGTGTATGGGGATTATAGTATCTTCTTGGCAGAAATTGCATCCACAACGAATGAAAACATCATGACAGAAGC
TCTCTTAAATGAAGTGCAAGATGAGAAAGAACGCTTTGCCATTTTAAACCATTACCTCGATGGTTTCCGTGGAACAGTTT
TCCGTCAAACCCAATTTGCTGAGTTTGAACATGCCATTCATCAAGCTGATCAAAAAGGAGAAGTGTTAACAAGTGAATAC
CTTAACCAGCTATACGCTGATTTAAATGAAAAATATTATGGTTTAAGTAAAAAAGATAATCATTTTATTCAGTATGAATG
GGCACGTATTCCTCATTTCTATTACAATTATTATGTTTACCAATATGCAACAGGGTTTGCAGCTGCAAGCTATTTAGCGG
ATAAGATTGTGCATGGCACACAAGATGATATCGATCATTACTTGGCCTACCTCAAGTCAGGAAATTCTGATTACCCACTT
GAAGTGATTGCTAAAGCAGGCGTTGATATGGCAAAAGGTGATTATTTGGAAGCTGCCTTTAAAGTCTTTGACGAACGTCT
AACAGAACTTGAAGTACTCGTGTCCAAAGGCATACACAAAAGCTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pepF | Streptococcus salivarius strain HSISS4 |
70.715 |
100 |
0.707 |