Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   RG52_RS08855 Genome accession   NZ_CP010177
Coordinates   1763469..1764101 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain H14     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1758469..1769101
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RG52_RS08830 (RG52_08435) yhfG 1758601..1758768 (+) 168 WP_000736860.1 YhfG family protein -
  RG52_RS08835 (RG52_08440) fic 1758758..1759360 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  RG52_RS08840 (RG52_08445) pabA 1759392..1759955 (+) 564 WP_000601844.1 aminodeoxychorismate synthase component 2 -
  RG52_RS08845 (RG52_08450) argD 1760041..1761261 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  RG52_RS08850 (RG52_08455) yhfK 1761328..1763418 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  RG52_RS08855 (RG52_08460) crp 1763469..1764101 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  RG52_RS08865 (RG52_08470) yhfA 1764403..1764807 (+) 405 WP_001148908.1 OsmC family protein -
  RG52_RS08870 (RG52_08475) prkB 1764862..1765731 (-) 870 WP_001274680.1 phosphoribulokinase -
  RG52_RS08875 (RG52_08480) yheU 1765785..1766003 (-) 219 WP_000907085.1 YheU family protein -
  RG52_RS08880 (RG52_08485) yheT 1765997..1767019 (-) 1023 WP_000057356.1 hydrolase -
  RG52_RS08885 (RG52_08490) yheS 1767019..1768932 (-) 1914 WP_000634793.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=117233 RG52_RS08855 WP_000242755.1 1763469..1764101(-) (crp) [Escherichia coli strain H14]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=117233 RG52_RS08855 WP_000242755.1 1763469..1764101(-) (crp) [Escherichia coli strain H14]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment