Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   DYB47_RS08950 Genome accession   NZ_UHFV01000002
Coordinates   1776121..1778562 (-) Length   813 a.a.
NCBI ID   WP_003081149.1    Uniprot ID   G5JW66
Organism   Streptococcus macacae NCTC 11558     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1771121..1783562
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DYB47_RS08925 (NCTC11558_01811) ptcA 1771122..1772141 (-) 1020 WP_003081109.1 putrescine carbamoyltransferase -
  DYB47_RS08930 (NCTC11558_01812) - 1772377..1773321 (+) 945 WP_003080449.1 response regulator transcription factor -
  DYB47_RS08935 (NCTC11558_01813) - 1773444..1774046 (-) 603 WP_003079738.1 nitroreductase family protein -
  DYB47_RS08940 (NCTC11558_01814) hslO 1774198..1775073 (+) 876 WP_003082437.1 Hsp33 family molecular chaperone HslO -
  DYB47_RS08945 (NCTC11558_01815) dusB 1775057..1776034 (+) 978 WP_003079353.1 tRNA dihydrouridine synthase DusB -
  DYB47_RS08950 (NCTC11558_01816) clpC 1776121..1778562 (-) 2442 WP_003081149.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  DYB47_RS08955 (NCTC11558_01817) - 1778568..1779023 (-) 456 WP_003078775.1 CtsR family transcriptional regulator -
  DYB47_RS08960 (NCTC11558_01818) - 1779196..1779660 (+) 465 WP_003082389.1 COG2426 family protein -
  DYB47_RS08965 (NCTC11558_01819) - 1779856..1781652 (-) 1797 WP_003080134.1 DHA2 family efflux MFS transporter permease subunit -
  DYB47_RS08970 (NCTC11558_01820) - 1781831..1782373 (+) 543 WP_003081357.1 TetR/AcrR family transcriptional regulator -
  DYB47_RS08975 (NCTC11558_01821) - 1782515..1783057 (-) 543 WP_002277500.1 TetR/AcrR family transcriptional regulator -

Sequence

Protein


Download         Length: 813 a.a.        Molecular weight: 90880.55 Da        Isoelectric Point: 6.7410

>NTDB_id=1171340 DYB47_RS08950 WP_003081149.1 1776121..1778562(-) (clpC) [Streptococcus macacae NCTC 11558]
MTHYSLKMQEVFRLAQFEAARYQSAYLESWHILLAMVEIDSSVAGLSFAEFEADVQFEEYQAAVILAVGRTPQKPKGKLT
LLEQSHALRKLLAEAEAISQVTHAKEVGTEHVLFTMLLNPNLLATRILELVGFRAKEDGEAVRLVDLRRVVERQAGFTKE
DLKAIFEMRKPKKNKTGNHFSDLMKPPSMTGELADFTRDLTELARQGRLEPVVGREEEISRMIQILSRKTKNNPVLVGEA
GVGKTALAYGLAQRIVDSAVPFELAAMKVLELDMMSVVAGTRFRGDFEERMNQIISDIEADGHIILFIDELHTIMGSGSG
IDSTLDAANILKPALARGSLRTVGATTQEEYQKHIEKDAALSRRFAKITIEEPSVEEAYQILLGLKKSYEDYHYVSISDE
TVMTAVKSAHRYLTSKHLPDSAIDLLDETSATVQGLVKKEAPAFLTELDNALLNGDFTQAKKLLKKKEEPLLKKRAAVTE
TDILKTLSKLSGIPVSKLNQTDSRKYLNLEKELHKRVIGQDEAVSSVSRAIRRNQSGIRTGRRPIGSFMFLGPTGVGKTE
LAKALAEILFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYAVLLFDEVEKAHPDIFNILLQV
LDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGVKNIAHDYKAMESRILEELKKTYRPEFINRIDEKVVFHS
LSQNNMRDVVKIMVQPLIAHLAEKNISLKFQPSALKFLAESGYDIEMGARPLRRTLQTEVEDKLAEFLLSGELSSGHSLK
IGVHKDRLKFDLI

Nucleotide


Download         Length: 2442 bp        

>NTDB_id=1171340 DYB47_RS08950 WP_003081149.1 1776121..1778562(-) (clpC) [Streptococcus macacae NCTC 11558]
ATGACCCATTACTCATTAAAAATGCAAGAAGTCTTTAGATTAGCACAATTTGAAGCTGCCCGCTACCAGAGTGCTTATTT
GGAAAGCTGGCATATTCTTCTGGCAATGGTGGAGATTGATAGTTCGGTTGCAGGTTTAAGTTTTGCAGAATTTGAGGCGG
ATGTTCAATTTGAAGAATATCAAGCTGCTGTTATTTTAGCTGTGGGCCGTACCCCTCAAAAACCAAAGGGGAAGCTAACC
TTATTAGAACAATCGCATGCTTTGCGCAAGCTCTTAGCAGAGGCAGAAGCAATCAGTCAGGTAACGCATGCGAAAGAAGT
TGGGACAGAGCATGTTTTATTTACTATGCTTTTAAATCCTAATTTATTAGCGACACGTATTCTAGAGCTGGTTGGTTTTC
GAGCAAAAGAAGATGGAGAAGCTGTCCGTTTGGTTGATTTGCGCAGGGTAGTAGAGCGTCAGGCTGGTTTTACCAAAGAA
GATCTTAAGGCTATTTTTGAGATGCGCAAACCTAAGAAAAATAAAACAGGAAATCATTTTTCGGACTTGATGAAACCGCC
TAGTATGACGGGAGAATTAGCTGATTTTACAAGGGATTTGACAGAATTGGCCCGCCAAGGCCGCTTAGAGCCTGTTGTTG
GCCGTGAAGAAGAAATTTCTCGTATGATTCAAATCCTTAGCCGTAAAACTAAAAATAACCCTGTGCTGGTTGGAGAAGCT
GGTGTTGGTAAGACAGCTTTGGCTTATGGATTAGCTCAGCGTATTGTAGATAGTGCTGTTCCTTTTGAATTGGCAGCTAT
GAAGGTCCTTGAATTGGATATGATGAGTGTAGTTGCAGGAACTCGTTTTCGCGGAGATTTCGAAGAACGCATGAATCAGA
TTATCTCTGATATTGAGGCTGATGGTCATATCATTCTCTTTATTGATGAGCTGCATACCATTATGGGATCAGGAAGCGGT
ATTGACAGCACACTTGATGCAGCTAATATTCTAAAGCCTGCTTTAGCCAGAGGCAGTCTTAGGACAGTAGGCGCGACAAC
ACAAGAAGAATATCAAAAACACATTGAAAAGGATGCCGCACTTTCACGCCGTTTTGCTAAGATTACAATTGAAGAACCAA
GTGTAGAAGAAGCTTATCAAATACTTCTTGGCTTGAAAAAAAGTTACGAAGATTATCACTATGTCAGTATTTCAGATGAG
ACGGTTATGACAGCTGTCAAGTCAGCACACCGCTATTTAACCAGTAAGCATCTGCCAGATTCAGCCATTGATCTATTGGA
TGAAACAAGCGCGACTGTACAAGGTCTGGTAAAAAAAGAAGCACCAGCTTTTCTAACCGAATTGGATAATGCTTTATTGA
ATGGTGATTTTACACAGGCTAAAAAACTGTTAAAGAAAAAAGAAGAGCCTTTGCTAAAAAAACGTGCAGCAGTAACTGAA
ACAGATATTTTGAAAACTTTAAGCAAGCTCTCTGGTATACCTGTCAGCAAACTAAACCAGACAGATAGTCGAAAATACCT
TAATCTTGAAAAAGAGCTGCATAAACGTGTGATTGGTCAAGACGAGGCTGTATCAAGTGTCAGCCGCGCTATCCGGCGCA
ATCAATCCGGAATCCGTACTGGGAGACGCCCTATTGGTTCCTTTATGTTTTTGGGGCCTACAGGTGTTGGAAAGACAGAA
TTGGCAAAAGCTTTAGCTGAGATTCTTTTTGATGATGAATCAGCACTCATTCGTTTTGATATGAGTGAGTATATGGAAAA
ATTTGCTGCCTCGCGTCTGAATGGAGCTCCTCCGGGCTATGTAGGCTATGAAGAAGGCGGTGAATTAACTGAAAAAGTCC
GCAATAAGCCTTATGCTGTCCTTCTTTTTGATGAAGTAGAAAAGGCCCATCCTGATATTTTCAATATTTTGCTGCAGGTT
TTAGATGATGGCGTTTTAACGGATAGCCGCGGCCGCAAAGTAGATTTTTCCAATACGATTATTATTATGACGTCTAACTT
GGGGGCAACGGCTTTACGTGATGACAAGACAGTCGGTTTTGGTGTTAAAAATATTGCTCATGATTATAAAGCGATGGAAT
CTCGTATCTTAGAGGAACTTAAAAAGACTTATCGTCCTGAGTTTATCAATCGGATTGATGAAAAAGTTGTCTTTCATAGT
CTCAGTCAGAACAATATGCGTGACGTTGTTAAAATTATGGTTCAGCCCTTGATTGCGCATCTTGCAGAAAAAAATATTTC
TCTTAAATTCCAGCCATCTGCCCTTAAGTTTTTGGCAGAAAGTGGATATGACATTGAAATGGGGGCAAGACCCTTACGCC
GAACCCTTCAAACAGAAGTAGAGGATAAGCTGGCAGAATTTCTTCTTTCAGGAGAGCTATCTAGCGGTCATTCCCTAAAA
ATTGGTGTTCATAAGGACAGGCTTAAATTTGATTTGATTTAA

Domains

Predicted by InterproScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(235-366)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(721-800)

AAA domain (Cdc48 subfamily) (AAA_2)

(543-714)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(15-55)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(102-134)

AAA lid domain (AAA_lid_9)

(374-455)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G5JW66

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus mutans UA159

84.748

100

0.847
  clpC Streptococcus thermophilus LMD-9

71.324

100

0.716
  clpC Streptococcus thermophilus LMG 18311

71.201

100

0.715
  clpC Streptococcus pneumoniae Rx1

68.428

100

0.685
  clpC Streptococcus pneumoniae D39

68.428

100

0.685
  clpC Streptococcus pneumoniae TIGR4

68.305

100

0.684
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

49.639

100

0.508
  clpC Bacillus subtilis subsp. subtilis str. 168

44.97

100

0.456
  clpE Streptococcus pneumoniae Rx1

47.604

76.999

0.367
  clpE Streptococcus pneumoniae D39

47.604

76.999

0.367
  clpE Streptococcus pneumoniae R6

47.604

76.999

0.367
  clpE Streptococcus mutans UA159

48.214

75.769

0.365
  clpE Streptococcus pneumoniae TIGR4

47.284

76.999

0.364

Multiple sequence alignment