Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   ACLV7D_RS07020 Genome accession   NZ_OZ217345
Coordinates   1432763..1435021 (+) Length   752 a.a.
NCBI ID   WP_218764161.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis F22     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1427763..1440021
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7D_RS06990 (SMIF22_13780) - 1427975..1428847 (-) 873 WP_218764163.1 NAD(P)H-hydrate dehydratase -
  ACLV7D_RS06995 (SMIF22_13790) - 1428906..1429679 (-) 774 WP_164226965.1 HAD hydrolase family protein -
  ACLV7D_RS07000 (SMIF22_13800) - 1429684..1430541 (-) 858 WP_218764162.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  ACLV7D_RS07005 (SMIF22_13810) - 1430695..1431429 (-) 735 WP_000140954.1 amino acid ABC transporter ATP-binding protein -
  ACLV7D_RS07010 (SMIF22_13820) - 1431429..1432112 (-) 684 WP_001011642.1 amino acid ABC transporter permease -
  ACLV7D_RS07015 (SMIF22_13830) - 1432302..1432532 (+) 231 WP_000443574.1 DUF1797 family protein -
  ACLV7D_RS07020 (SMIF22_13840) clpE 1432763..1435021 (+) 2259 WP_218764161.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  ACLV7D_RS07025 (SMIF22_13850) - 1435152..1435604 (+) 453 WP_218764160.1 NUDIX hydrolase -
  ACLV7D_RS07030 - 1435601..1435747 (-) 147 WP_000693452.1 hypothetical protein -
  ACLV7D_RS07035 (SMIF22_13860) - 1435815..1436114 (+) 300 WP_000767194.1 DUF1827 family protein -
  ACLV7D_RS07040 (SMIF22_13870) - 1436294..1437550 (+) 1257 WP_173217988.1 ISL3 family transposase -
  ACLV7D_RS07045 (SMIF22_13880) ezrA 1437723..1439450 (-) 1728 WP_164226787.1 septation ring formation regulator EzrA -

Sequence

Protein


Download         Length: 752 a.a.        Molecular weight: 83793.21 Da        Isoelectric Point: 5.3713

>NTDB_id=1170378 ACLV7D_RS07020 WP_218764161.1 1432763..1435021(+) (clpE) [Streptococcus mitis isolate S. mitis F22]
MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSLFKGMTDLNNRDFDPFGDFFNDLNNFRPSNNTPPIPP
TQSGGGYGGNGGYGSQNRGSAQTPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKREDIILFIDEIHEIVGAGSA
SDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAA
IEAAATLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRDQIAKYKEM
QKKKVTDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKSHVIGQDDAVDKIAKAIRRNRVGLGTPNRPI
GSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDE
VEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKAEASVGFGAAREGRTNSVLGELGNFFSPEFMNRF
DGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYLENP
SEKDLKAVMTSKGNIQIKSAKKAEVKSSEKEK

Nucleotide


Download         Length: 2259 bp        

>NTDB_id=1170378 ACLV7D_RS07020 WP_218764161.1 1432763..1435021(+) (clpE) [Streptococcus mitis isolate S. mitis F22]
ATGCTTTGTCAAAACTGTAAAATCAACGACTCAACAATTCATCTTTACACCAATCTCAATGGAAAACAAAAACAAATTGA
CCTCTGTCAAAACTGCTATAAGATTATCAAAACAGATCCTAACAATAGCCTCTTCAAAGGTATGACGGATCTGAACAATC
GTGACTTTGATCCCTTTGGTGATTTCTTCAATGATCTAAACAATTTCAGACCTTCTAACAACACTCCTCCTATTCCCCCA
ACCCAATCAGGTGGAGGTTACGGTGGAAACGGCGGTTATGGTTCCCAAAATCGTGGTTCTGCTCAAACTCCACCACCAAG
CCAAGAAAAAGGCCTGCTGGAAGAATTTGGTATCAACGTAACTGAGATTGCCCGTCGTGGAGACATTGACCCCGTTATTG
GGCGCGACGATGAGATTATCCGTGTCATCGAAATTCTCAATCGTAGAACTAAGAATAATCCTGTTCTTATCGGTGAACCA
GGTGTCGGAAAAACTGCTGTTGTCGAAGGTCTAGCTCAGAAAATCGTTGATGGCGATGTTCCACATAAACTCCAAGGTAA
ACAAGTCATCCGTCTGGATGTGGTTAGTCTGGTCCAAGGAACGGGTATCCGAGGACAATTTGAAGAACGCATGCAAAAAC
TCATGGAAGAAATTCGCAAACGTGAGGACATCATTCTCTTTATTGATGAAATCCATGAAATTGTTGGTGCTGGTTCTGCG
AGTGATGGTAATATGGACGCAGGAAATATCCTCAAGCCAGCCCTTGCTCGTGGGGAACTGCAACTGGTCGGTGCCACTAC
CCTCAATGAATACCGTATCATTGAAAAGGATGCTGCCCTCGAGCGTCGTATGCAGCCTGTTAAAGTCGATGAACCAACGG
TGGACGAAACAATCACTATTCTCAAAGGGATTCAAAAGAAATACGAAGACTACCACCACGTTCAGTATACTGATGCTGCG
ATTGAAGCAGCTGCAACTCTTTCTAATCGCTACATCCAAGATCGCTTCTTACCTGACAAGGCCATTGACCTCCTAGATGA
AGCAGGTTCTAAGATGAACTTGACCTTGAATTTTGTAGATCCTAAAGTCATTGATCAGCGCTTGATTGAGGCTGAAAATC
TCAAATCTCAAGCTACACGAGAGGAAGATTTTGAGAAGGCCGCCTATTTCCGTGACCAGATTGCCAAATATAAGGAAATG
CAAAAGAAAAAGGTCACAGACCAAGATACACCTATCATCAGTGAGAAAACCATTGAGCACATTATCGAACAGAAAACCAA
CATCCCTGTTGGTGATTTAAAAGAGAAAGAACAATCTCAACTCATCCATCTAGCCGAAGATCTCAAGTCTCATGTTATTG
GCCAAGATGATGCAGTTGATAAGATTGCCAAGGCTATTCGCCGTAATCGTGTCGGTCTCGGTACGCCTAACCGCCCAATT
GGAAGCTTCCTCTTTGTCGGACCAACTGGGGTCGGTAAGACAGAACTTTCCAAACAACTAGCTATCGAACTCTTTGGTTC
TGCTGACAGCATGATTCGCTTTGATATGAGTGAATATATGGAAAAACACAGTGTAGCTAAATTAGTTGGTGCCCCTCCAG
GTTATGTTGGCTACGATGAGGCTGGGCAATTAACTGAAAAAGTTCGCCGCAATCCATATTCTCTCATCCTTCTCGATGAA
GTGGAAAAAGCTCACCCAGATGTTATGCACATGTTTCTACAAGTCTTGGACGATGGTCGTTTGACAGATGGACAAGGACG
CACCGTTAGTTTCAAAGATGCCATCATTATCATGACTTCAAATGCAGGTACAGGTAAGGCAGAAGCCAGCGTTGGATTTG
GGGCTGCTAGAGAAGGACGTACCAACTCTGTTCTCGGTGAACTCGGCAACTTCTTTAGCCCAGAGTTTATGAACCGTTTT
GATGGTATTATCGAATTTAAGGCTCTCAGCAAAGATAACCTCCTTCAGATTGTCGAGCTCATGCTAGCAGATGTTAACAA
ACGTCTTTCTAGCAACAACATTCATTTAGATGTAACTGACAAGGTCAAGGAAAAATTAGTTGACCTCGGTTATGATCCAA
AAATGGGAGCACGCCCACTTCGCCGCACTATTCAAGACTATATTGAAGACGCAATCACTGATTACTACCTTGAAAATCCA
AGCGAAAAAGATCTCAAAGCAGTTATGACTAGCAAGGGAAACATTCAGATTAAATCTGCCAAAAAAGCTGAAGTTAAAAG
TTCTGAAAAAGAAAAATAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(649-723)

AAA lid domain (AAA_lid_9)

(293-390)

ATPase family associated with various cellular activities (AAA) (AAA)

(155-276)

AAA domain (Cdc48 subfamily) (AAA_2)

(478-641)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

99.202

100

0.992
  clpE Streptococcus pneumoniae D39

99.202

100

0.992
  clpE Streptococcus pneumoniae R6

99.202

100

0.992
  clpE Streptococcus pneumoniae TIGR4

99.069

100

0.991
  clpE Streptococcus mutans UA159

83.266

99.335

0.827
  clpC Lactococcus lactis subsp. cremoris KW2

77.384

97.606

0.755
  clpC Bacillus subtilis subsp. subtilis str. 168

52.462

86.436

0.453
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.006

83.378

0.4
  clpC Streptococcus pneumoniae Rx1

46.91

83.91

0.394
  clpC Streptococcus pneumoniae D39

46.91

83.91

0.394
  clpC Streptococcus pneumoniae TIGR4

46.91

83.91

0.394
  clpC Streptococcus mutans UA159

46.73

83.378

0.39
  clpC Streptococcus thermophilus LMD-9

46.795

82.979

0.388
  clpC Streptococcus thermophilus LMG 18311

46.4

83.112

0.386

Multiple sequence alignment