Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   ACLV7D_RS06230 Genome accession   NZ_OZ217345
Coordinates   1275794..1277596 (-) Length   600 a.a.
NCBI ID   WP_173233955.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis F22     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 1270794..1282596
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7D_RS06195 (SMIF22_12180) - 1271275..1272117 (+) 843 WP_112443626.1 DUF368 domain-containing protein -
  ACLV7D_RS06200 (SMIF22_12190) - 1272117..1272599 (+) 483 WP_218764128.1 aminoacyl-tRNA deacylase -
  ACLV7D_RS06205 (SMIF22_12200) - 1272599..1273219 (+) 621 WP_173274465.1 histidine phosphatase family protein -
  ACLV7D_RS06210 - 1273498..1273656 (-) 159 WP_025173180.1 hypothetical protein -
  ACLV7D_RS06215 - 1273668..1273763 (-) 96 Protein_1177 IS630 family transposase -
  ACLV7D_RS06220 (SMIF22_12210) prsA 1274071..1275012 (-) 942 WP_173233959.1 peptidylprolyl isomerase PrsA -
  ACLV7D_RS06225 (SMIF22_12220) - 1275079..1275792 (-) 714 WP_173233957.1 O-methyltransferase -
  ACLV7D_RS06230 (SMIF22_12230) pepF 1275794..1277596 (-) 1803 WP_173233955.1 oligoendopeptidase F Regulator
  ACLV7D_RS06235 (SMIF22_12240) coiA 1277615..1278568 (-) 954 WP_218764127.1 competence protein CoiA Machinery gene
  ACLV7D_RS06240 (SMIF22_12250) - 1278647..1279024 (-) 378 WP_173233951.1 type II toxin-antitoxin system HicB family antitoxin -
  ACLV7D_RS06245 - 1279052..1279243 (-) 192 WP_173234128.1 type II toxin-antitoxin system HicA family toxin -
  ACLV7D_RS06250 (SMIF22_12260) tehB 1279467..1280327 (-) 861 WP_218764126.1 SAM-dependent methyltransferase TehB -
  ACLV7D_RS06255 (SMIF22_12270) smpB 1280342..1280809 (-) 468 WP_001051750.1 SsrA-binding protein SmpB -

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 69911.83 Da        Isoelectric Point: 4.5671

>NTDB_id=1170373 ACLV7D_RS06230 WP_173233955.1 1275794..1277596(-) (pepF) [Streptococcus mitis isolate S. mitis F22]
MVLQRNEINEKDTWDLSTIYPTDQAWEEALKELTEQLETVARYEGHLLDSADSLLEITEFSLEMERQMEKLYVYAHMKND
QDTREAKYQEYYAKAMTLYSQLDQAFSFYEPEFMEISEKQYTDFLEAQPKLQVYQHYFDKLLQGKEHVLSQREEELLAGA
GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKNREVRRGAYQALYATYQQFQHTYAKTLQTNVKVQ
NYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRKHLPLLHRYLELRSKILGISDLKMYDVYTPLSSVDYSFTYQEALK
KAEDALAVLGEDYLSRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSMHSSYTRET
QPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFRGTVFRQTQFAEFEHAIHQADQNGEVLTSDF
LNKLYADLNQEYYGLSKEDNPEIQYEWARIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPL
NVMRKAGVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=1170373 ACLV7D_RS06230 WP_173233955.1 1275794..1277596(-) (pepF) [Streptococcus mitis isolate S. mitis F22]
ATGGTATTACAAAGAAATGAAATAAATGAAAAAGATACATGGGATCTATCAACGATTTACCCAACTGACCAGGCTTGGGA
AGAAGCCTTAAAAGAGTTAACAGAACAACTGGAGACAGTGGCTCGGTATGAAGGTCATCTCTTGGATAGTGCGGATAGCC
TACTCGAAATTACTGAATTTTCTCTTGAAATGGAACGCCAAATGGAGAAGCTTTACGTTTATGCTCATATGAAAAATGAC
CAGGATACACGTGAAGCCAAGTACCAAGAGTATTACGCCAAGGCAATGACTCTCTACAGCCAGCTAGACCAAGCCTTTTC
ATTCTATGAACCTGAATTTATGGAAATTAGTGAAAAGCAGTATACTGACTTTTTAGAGGCTCAACCAAAATTGCAGGTTT
ATCAACACTATTTTGATAAGCTTTTACAAGGTAAGGAACACGTTCTTTCACAACGCGAAGAAGAATTATTGGCTGGAGCT
GGGGAAATCTTTGGTTCGGCAAGTGAAACTTTCGCTATCTTGGACAATGCGGATATTGTTTTCCCTTATGTTCTTGACGA
TGATGGTAAGGAAGTTCAGCTATCTCATGGGACTTACACACGTTTGATGGAGTCTAAAAATCGTGAGGTGCGTCGTGGTG
CTTATCAAGCTCTTTATGCGACTTATCAACAATTCCAACACACCTATGCTAAAACCTTGCAAACCAATGTTAAGGTGCAA
AACTATCGTGCTAAAGTTCGCAACTACAAGAGCGCTCGTCATGCAGCCCTAGCGGCTAATTTTGTTCCAGAAAGTGTTTA
TGACAATTTGGTAGCAGCAGTTCGCAAGCATTTGCCACTCTTGCATCGTTACCTTGAACTTCGTTCAAAAATCTTGGGAA
TTTCAGATCTCAAGATGTACGATGTCTACACACCGCTTTCGTCAGTAGATTATAGTTTCACCTACCAAGAAGCCTTGAAA
AAGGCAGAAGATGCCTTGGCAGTCTTGGGTGAAGATTACTTGAGCCGTGTTAAACGTGCTTTCAGTGAGCGTTGGATTGA
CGTTTATGAAAATCAAGGCAAGCGTTCAGGGGCTTACTCTGGTGGTTCTTACGATACCAATGCCTTCATGCTTCTTAACT
GGCAGGACAATCTAGACAATCTTTTTACTCTTGTTCATGAAACTGGTCACAGTATGCACTCAAGCTATACTCGCGAAACT
CAGCCTTATGTTTACGGGGATTACTCTATTTTCTTGGCTGAGATTGCATCAACTACCAATGAAAATATCTTGACGGAGAA
ATTATTGGAAGAAGTGGAAGATGACGCAACGCGCTTTGCTATTCTCAATAACTTCCTAGACGGTTTCCGTGGAACAGTTT
TCCGCCAAACTCAATTTGCTGAGTTTGAACACGCGATTCACCAAGCGGATCAAAATGGTGAAGTCTTGACAAGCGATTTC
TTAAATAAACTCTACGCAGACTTGAACCAAGAGTATTATGGTTTGAGTAAGGAAGACAATCCTGAAATCCAATACGAGTG
GGCACGCATTCCACACTTCTACTATAACTACTATGTATACCAATATTCAACAGGATTTGCAGCAGCCTCAGCCTTGGCTG
AAAAGATTGTTCATGGTAGTCAAGAAGACCGTGACCGCTATATCGACTACCTCAAGGCAGGTAAGTCTGACTATCCACTT
AATGTCATGAGAAAAGCTGGAGTTGATATGGAGAAGGAAGACTATCTCAACGATGCCTTTGCAGTCTTTGAACGTCGTTT
GAATGAGTTTGAAGCCCTTGTTGAAAAATTGGGATTGGCATAA

Domains

Predicted by InterproScan.

Oligopeptidase F (Peptidase_M3_N)

(112-181)

Peptidase family M3 (Peptidase_M3)

(202-581)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

66.611

99.333

0.662

Multiple sequence alignment