Detailed information NTG1170343

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: ACLV7D_RS01550
• Genome accession: NZ_OZ217345
• Coordinates: 294802..295626 (+)
• Length: 274 a.a.
• NCBI ID: WP_218764450.1
• Uniprot ID: -
• Organism: Streptococcus mitis isolate S. mitis F22
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 289802..300626

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV7D_RS01525 (SMIF22_02930)	rsmD	290948..291487 (+)	540	WP_218764453.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
ACLV7D_RS01530 (SMIF22_02950)	-	291477..292987 (+)	1511	Protein_268	SepM family pheromone-processing serine protease	-
ACLV7D_RS01535 (SMIF22_02960)	-	293045..293275 (+)	231	WP_078156193.1	DUF1146 family protein	-
ACLV7D_RS01540 (SMIF22_02970)	murA	293299..294582 (+)	1284	WP_173212201.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
ACLV7D_RS01545 (SMIF22_02980)	-	294569..294763 (+)	195	WP_050236587.1	DNA-directed RNA polymerase subunit beta	-
ACLV7D_RS01550 (SMIF22_02990)	endA	294802..295626 (+)	825	WP_218764450.1	DNA/RNA non-specific endonuclease	Machinery gene
ACLV7D_RS01555 (SMIF22_03000)	-	295781..297112 (+)	1332	WP_218764449.1	hemolysin family protein	-

Sequence

Protein

• Length: 274 a.a.
• Molecular weight: 29795.33 Da
• Isoelectric Point: 9.8711

>NTDB_id=1170343 ACLV7D_RS01550 WP_218764450.1 294802..295626(+) (endA) [Streptococcus mitis isolate S. mitis F22]
MNKKTRQTLIGLLVLLLLSAGSYYIKQNELGNQAAKTKISQKSQSPDAPGQELAESVLTDAVKSQIKGSLEWNGAGAFIV
NGNKTNLNAKVSSKPYADNKTKTVGKETVPAVANALLSKATRQYKNREETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEDSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide

• Length: 825 bp

>NTDB_id=1170343 ACLV7D_RS01550 WP_218764450.1 294802..295626(+) (endA) [Streptococcus mitis isolate S. mitis F22]
ATGAACAAAAAAACAAGACAGACACTGATTGGCTTGCTAGTGTTATTGCTCTTATCTGCGGGGAGCTATTATATTAAGCA
GAATGAACTAGGCAATCAGGCTGCTAAGACAAAAATAAGTCAGAAAAGTCAATCACCAGACGCGCCTGGTCAAGAATTGG
CGGAAAGTGTCTTAACAGATGCAGTCAAAAGCCAAATAAAAGGGAGTCTGGAGTGGAACGGGGCTGGTGCTTTTATCGTC
AATGGTAATAAAACAAACCTAAATGCCAAGGTTTCAAGTAAGCCCTACGCTGATAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAGCCGTGGCTAATGCCCTCTTGTCTAAGGCCACTCGCCAGTACAAGAATCGTGAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTTAAGAATCTAAAGGGCTCTTATACCCATGCCGTTGATAGAGGGCAC
TTGTTAGGCTATGCCTTAATCGGTGGCTTGGATGGTTTTGATGCCTCAACAAGCAATCCCAAAAACATTGCTGTTCAAAC
AGCCTGGGCAAATCAGGCGCAAGCCGAGGATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTATTACGCTTCAAACGAGGATTTAGTTCCTTCAGCTTCACAGATTGAA
GCCAAGTCTTCAGACGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTCCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACGGTAACTCAGTAA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (76-247)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	91.971	100	0.92
endA	Streptococcus pneumoniae D39	91.971	100	0.92
endA	Streptococcus pneumoniae R6	91.971	100	0.92
endA	Streptococcus pneumoniae TIGR4	91.971	100	0.92