Detailed information    

insolico Bioinformatically predicted

Overview

Name   rcrP   Type   Regulator
Locus tag   ACLV7Z_RS01760 Genome accession   NZ_OZ217343
Coordinates   335628..337397 (+) Length   589 a.a.
NCBI ID   WP_218774548.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis G22     
Function   regulate competence (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 316979..346370 335628..337397 within 0


Gene organization within MGE regions


Location: 316979..346370
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7Z_RS01675 (SMIG22_03270) cinA 316979..318235 (+) 1257 WP_218774541.1 competence/damage-inducible protein A Machinery gene
  ACLV7Z_RS01680 (SMIG22_03280) recA 318290..319456 (+) 1167 WP_023933324.1 recombinase RecA Machinery gene
  ACLV7Z_RS01685 (SMIG22_03290) - 319572..320942 (+) 1371 WP_218774542.1 MATE family efflux transporter -
  ACLV7Z_RS01690 (SMIG22_03300) - 321311..322261 (+) 951 WP_173212168.1 N-acetylmuramoyl-L-alanine amidase -
  ACLV7Z_RS01695 (SMIG22_03310) - 322632..322976 (+) 345 WP_218774543.1 helix-turn-helix domain-containing protein -
  ACLV7Z_RS01700 (SMIG22_03320) - 322989..323735 (+) 747 WP_411882185.1 ImmA/IrrE family metallo-endopeptidase -
  ACLV7Z_RS01705 (SMIG22_03330) - 323728..324150 (+) 423 Protein_302 hypothetical protein -
  ACLV7Z_RS01710 (SMIG22_03340) - 324874..325428 (+) 555 WP_306416194.1 PBECR4 domain-containing protein -
  ACLV7Z_RS01715 (SMIG22_03350) - 326211..327701 (+) 1491 WP_225904910.1 YSIRK-type signal peptide-containing protein -
  ACLV7Z_RS01720 (SMIG22_03360) - 327783..328127 (+) 345 WP_218774545.1 hypothetical protein -
  ACLV7Z_RS01725 (SMIG22_03370) - 328155..330398 (+) 2244 WP_411882186.1 DUF1542 domain-containing protein -
  ACLV7Z_RS01730 (SMIG22_03380) - 330710..331168 (+) 459 WP_031233612.1 DUF4231 domain-containing protein -
  ACLV7Z_RS01735 (SMIG22_03390) - 331181..331789 (+) 609 WP_218764810.1 hypothetical protein -
  ACLV7Z_RS01740 (SMIG22_03400) - 331782..332192 (+) 411 WP_225904911.1 hypothetical protein -
  ACLV7Z_RS01745 (SMIG22_03410) ply 332203..333618 (+) 1416 WP_173214000.1 cholesterol-dependent cytolysin pneumolysin -
  ACLV7Z_RS01750 (SMIG22_03420) - 334288..335004 (+) 717 WP_000532882.1 YebC/PmpR family DNA-binding transcriptional regulator -
  ACLV7Z_RS01755 (SMIG22_03430) - 335183..335653 (+) 471 WP_218774547.1 MarR family winged helix-turn-helix transcriptional regulator -
  ACLV7Z_RS01760 (SMIG22_03440) rcrP 335628..337397 (+) 1770 WP_218774548.1 ABC transporter ATP-binding protein Regulator
  ACLV7Z_RS01765 (SMIG22_03450) rcrQ 337387..339147 (+) 1761 WP_218774549.1 ABC transporter ATP-binding protein Regulator
  ACLV7Z_RS01770 (SMIG22_03460) - 339243..339746 (+) 504 WP_218774550.1 phosphatase PAP2 family protein -
  ACLV7Z_RS01775 (SMIG22_03470) - 339966..340412 (+) 447 WP_218774551.1 LytTR family DNA-binding domain-containing protein -
  ACLV7Z_RS01780 (SMIG22_03480) - 340417..341091 (+) 675 WP_218774552.1 LiaF transmembrane domain-containing protein -
  ACLV7Z_RS01785 (SMIG22_03490) - 341334..341531 (+) 198 Protein_318 N-acetylmuramoyl-L-alanine amidase family protein -
  ACLV7Z_RS01790 (SMIG22_03500) - 341762..342061 (+) 300 WP_001815024.1 DUF4651 domain-containing protein -
  ACLV7Z_RS01795 (SMIG22_03510) - 342058..342375 (+) 318 WP_218774554.1 thioredoxin family protein -
  ACLV7Z_RS01800 (SMIG22_03520) ytpR 342390..343016 (+) 627 WP_218774555.1 YtpR family tRNA-binding protein -
  ACLV7Z_RS01805 (SMIG22_03530) - 343058..343819 (+) 762 WP_218774556.1 SDR family NAD(P)-dependent oxidoreductase -
  ACLV7Z_RS01810 (SMIG22_03540) ssbB/cilA 343897..344292 (+) 396 WP_000282442.1 single-stranded DNA-binding protein Machinery gene
  ACLV7Z_RS01815 (SMIG22_03550) groES 344448..344732 (+) 285 WP_000917336.1 co-chaperone GroES -
  ACLV7Z_RS01820 (SMIG22_03560) groL 344748..346370 (+) 1623 WP_218774557.1 chaperonin GroEL -

Sequence

Protein


Download         Length: 589 a.a.        Molecular weight: 65424.98 Da        Isoelectric Point: 6.8905

>NTDB_id=1170185 ACLV7Z_RS01760 WP_218774548.1 335628..337397(+) (rcrP) [Streptococcus mitis isolate S. mitis G22]
MKKLAKRISRKEWGMILLAILFTCFSVYLELEVPTYISKITDLLGTQGTNLDELWQPAGMMVGMSFLAFLSAVAVGFFAS
RVAASYTSRLRSDIFNRVLDYSQTEIKKFSIPSLLTRTTNDITQVQMLITMGLQVVTRGPIMAIWAIGKILGHSEYWLWA
VLVAVIVNVLMTTVLMTLAFPKQSLIQSLTDKLNSITRESLTGIRVVRAYNAEKYQNEKFAAANDGLTRLNLFVNRLMAI
LNPIMMGISSGLSVAIYWIGAYVINDAAPIVRLPLFSDMIVFMSYAMQVVMGFLLMGALFIVLPRTMVSAKRINQVLDLH
SSIQNPAQVQQADENLKGQVEFKDVTFRYAANSEAVIENVSFKAEAGQTVAFIGSTGSGKSTLVNLIPRFYDVSAGEIFV
DGVNVQDYALEDLRNKVGYIPQKAVLFSGDVKANLDFGQSQETPLSEQAMWQALELAQSKNFIEDKEAGLESEVTQGGIN
FSGGQRQRLAIARALARKPEILIFDDSFSALDYKTDRVLRQELAEKTKSMTKLIVAQRISTIMDADLILVLDQGKVVGQG
THKELLANNEVYQEIAYSQLSKEELEHGK

Nucleotide


Download         Length: 1770 bp        

>NTDB_id=1170185 ACLV7Z_RS01760 WP_218774548.1 335628..337397(+) (rcrP) [Streptococcus mitis isolate S. mitis G22]
ATGAAGAAATTAGCCAAACGAATTAGTAGAAAAGAATGGGGGATGATTTTACTAGCCATTCTCTTTACCTGCTTTTCGGT
CTATCTGGAGTTGGAAGTGCCGACCTATATCTCGAAAATTACGGATTTACTGGGAACTCAAGGAACAAACTTAGATGAGT
TATGGCAGCCAGCAGGTATGATGGTGGGAATGTCCTTTCTTGCCTTCTTGTCCGCAGTTGCAGTTGGATTTTTTGCGTCC
AGAGTGGCGGCTTCTTATACTAGTAGGCTAAGAAGTGATATTTTTAACCGAGTTTTGGATTACTCGCAGACAGAGATTAA
GAAATTCTCTATCCCTAGTCTCTTAACTCGTACCACCAATGATATTACTCAGGTTCAGATGTTGATTACCATGGGCTTGC
AAGTGGTTACGCGTGGTCCGATTATGGCTATCTGGGCCATCGGGAAGATTTTAGGCCATTCAGAATACTGGCTCTGGGCC
GTTCTTGTGGCAGTGATTGTCAACGTTTTGATGACGACTGTTTTGATGACGTTAGCCTTTCCAAAACAGTCCTTGATTCA
AAGTCTGACTGATAAACTGAACAGTATCACTCGTGAAAGTTTAACAGGTATTCGAGTCGTTCGTGCCTACAATGCCGAAA
AGTACCAAAATGAAAAATTTGCAGCAGCCAATGATGGATTGACACGTTTGAATTTGTTTGTCAACCGTCTTATGGCTATT
TTGAACCCTATCATGATGGGGATTTCAAGCGGTTTGAGTGTGGCGATTTACTGGATTGGGGCCTATGTGATTAACGACGC
TGCTCCGATAGTGCGTCTGCCTCTCTTTAGTGACATGATTGTTTTCATGTCTTATGCCATGCAGGTTGTCATGGGTTTCC
TTCTCATGGGAGCACTTTTCATCGTTCTTCCCCGAACTATGGTCTCTGCCAAGCGGATCAATCAAGTTCTAGATTTGCAT
TCGTCTATCCAAAACCCTGCTCAAGTGCAGCAGGCTGATGAAAACCTCAAAGGTCAGGTCGAATTTAAGGATGTGACCTT
CCGCTATGCGGCAAATTCGGAGGCGGTTATTGAGAATGTTAGCTTTAAAGCAGAAGCTGGCCAAACAGTGGCCTTTATTG
GGTCAACAGGTTCTGGTAAATCTACTCTAGTTAATCTGATTCCACGTTTCTACGACGTATCAGCAGGAGAGATTTTTGTA
GACGGTGTCAATGTTCAAGACTATGCCTTAGAAGATTTGCGCAACAAGGTTGGCTATATTCCACAAAAAGCTGTTCTCTT
TTCAGGTGATGTCAAGGCTAATCTAGACTTTGGACAGAGTCAAGAAACACCACTTAGTGAGCAGGCTATGTGGCAGGCCT
TGGAATTGGCCCAGTCTAAGAACTTTATCGAAGACAAGGAAGCGGGTTTAGAGTCAGAAGTGACCCAAGGAGGAATCAAC
TTCTCAGGTGGTCAAAGACAGCGTCTGGCCATTGCGCGTGCCTTGGCTCGGAAGCCAGAAATCCTCATCTTTGATGACTC
CTTCTCAGCCTTGGATTACAAGACAGACCGTGTCCTACGCCAAGAGTTAGCAGAGAAAACCAAGTCTATGACCAAGCTTA
TCGTCGCACAGCGTATTTCAACGATTATGGATGCTGATTTGATTTTGGTCTTGGATCAAGGAAAAGTCGTGGGACAAGGC
ACCCACAAGGAACTTCTAGCTAATAACGAAGTTTACCAAGAAATTGCCTATTCACAACTATCGAAGGAGGAATTGGAACA
TGGAAAATAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(17-292)

ABC transporter (ABC_tran)

(358-507)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rcrP Streptococcus mutans UA159

66.223

100

0.676

Multiple sequence alignment