Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   ACLV7Q_RS06160 Genome accession   NZ_OZ217341
Coordinates   1249986..1251788 (-) Length   600 a.a.
NCBI ID   WP_218757815.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis C22     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 1244986..1256788
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7Q_RS06130 (SMIC22_12030) - 1245560..1246402 (+) 843 WP_218757818.1 DUF368 domain-containing protein -
  ACLV7Q_RS06135 (SMIC22_12040) - 1246402..1246884 (+) 483 WP_218757817.1 aminoacyl-tRNA deacylase -
  ACLV7Q_RS06140 (SMIC22_12050) - 1246884..1247504 (+) 621 WP_218757816.1 histidine phosphatase family protein -
  ACLV7Q_RS06145 - 1247862..1247957 (-) 96 Protein_1163 IS630 family transposase -
  ACLV7Q_RS06150 (SMIC22_12060) prsA 1248266..1249204 (-) 939 WP_050211752.1 peptidylprolyl isomerase PrsA -
  ACLV7Q_RS06155 (SMIC22_12070) - 1249271..1249984 (-) 714 WP_004259562.1 O-methyltransferase -
  ACLV7Q_RS06160 (SMIC22_12080) pepF 1249986..1251788 (-) 1803 WP_218757815.1 oligoendopeptidase F Regulator
  ACLV7Q_RS06165 (SMIC22_12090) coiA 1251807..1252760 (-) 954 WP_218757814.1 competence protein CoiA Machinery gene
  ACLV7Q_RS06170 (SMIC22_12100) - 1252839..1253216 (-) 378 WP_050252888.1 type II toxin-antitoxin system HicB family antitoxin -
  ACLV7Q_RS06175 (SMIC22_12110) - 1253244..1253432 (-) 189 WP_001122912.1 type II toxin-antitoxin system HicA family toxin -
  ACLV7Q_RS06180 (SMIC22_12120) tehB 1253554..1254414 (-) 861 WP_218757813.1 SAM-dependent methyltransferase TehB -
  ACLV7Q_RS06185 (SMIC22_12130) smpB 1254429..1254896 (-) 468 WP_001051750.1 SsrA-binding protein SmpB -

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 69921.82 Da        Isoelectric Point: 4.5466

>NTDB_id=1170044 ACLV7Q_RS06160 WP_218757815.1 1249986..1251788(-) (pepF) [Streptococcus mitis isolate S. mitis C22]
MVLQRHEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVVQYEGHLLDSADSLLEITEFSLEMERQMEKIYVYAHMKND
QDTREAKYQEYYAKAMTLYSQLDQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQSKDHVLSQREEELLAGA
GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKNREVRRGAYQALYATYEQFQHTYAKTLQTNVKVQ
NYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRKHLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALK
KAEDALAVLGEDYLSRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSMHSSYTRET
QPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFRGTVFRQTQFAEFEHAIHQADQNGEVLTSDF
LNKLYADLNQEYYGLSKEDNPEIQYEWARIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPL
NVMRKAGVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=1170044 ACLV7Q_RS06160 WP_218757815.1 1249986..1251788(-) (pepF) [Streptococcus mitis isolate S. mitis C22]
ATGGTATTACAAAGACATGAAATAAATGAAAAAGATACATGGGATCTATCAACGATCTACCCAACTGACCAGGCTTGGGA
AGAAGCCTTAAAAGATTTAACAGAACAATTGGAGACAGTAGTCCAGTATGAAGGTCATCTCTTGGATAGTGCGGATAGCC
TACTCGAAATTACTGAATTTTCTCTTGAAATGGAACGCCAAATGGAGAAGATTTACGTTTATGCTCATATGAAAAATGAC
CAGGACACACGTGAAGCTAAGTATCAAGAGTATTACGCCAAGGCCATGACTCTCTATAGCCAGCTAGACCAAGCCTTTTC
ATTCTATGAACCTGAATTTATGGAGATTAGCGAAAAGCAGTATGCTGACTTTTTAGAAGCTCAACCAAAATTGCAGGTTT
ATCAACACTATTTTGACAAGCTCTTGCAAAGCAAGGATCACGTTCTTTCACAACGCGAAGAAGAATTATTAGCTGGAGCT
GGAGAAATCTTTGGTTCAGCAAGTGAAACCTTCGCTATTTTGGACAATGCGGATATTGTGTTCCCTTATGTCCTCGACGA
TGATGGTAAAGAAGTTCAGCTATCTCATGGGACCTACACACGTTTGATGGAGTCTAAAAATCGTGAGGTTCGCCGTGGGG
CCTATCAAGCCCTTTATGCGACTTATGAGCAATTCCAACACACCTATGCTAAAACCTTGCAAACCAATGTTAAGGTGCAA
AACTATCGTGCCAAAGTTCGCAACTACAAGAGCGCTCGTCATGCAGCCCTCGCAGCCAATTTTGTTCCAGAGAGTGTTTA
TGACAATTTGGTAGCAGCAGTTCGCAAGCATTTGCCACTCTTGCATCGTTACCTTGAGCTTCGTTCAAAAATCTTGGGGA
TTTCAGACCTCAAGATGTACGATGTCTACACACCACTTTCATCTGTTGAATACAGTTTTACCTACCAAGAAGCCTTGAAA
AAGGCAGAAGATGCCTTGGCAGTCTTGGGTGAGGATTACTTGAGCCGTGTTAAACGTGCCTTCAGTGAGCGTTGGATTGA
TGTTTATGAAAATCAAGGCAAGCGTTCAGGGGCTTACTCTGGTGGTTCTTACGATACAAATGCCTTTATGCTTCTTAACT
GGCAGGACAATCTGGACAATCTCTTTACTCTTGTTCATGAAACAGGTCACAGTATGCATTCTAGCTATACTCGCGAGACT
CAGCCTTATGTTTACGGAGATTATTCGATCTTCTTGGCTGAGATTGCCTCAACGACCAATGAAAATATTTTGACGGAGAA
ATTATTGGAAGAAGTGGAAGACGACGCAACGCGCTTTGCTATTCTCAATAACTTCCTAGATGGTTTCCGTGGGACAGTTT
TCCGCCAAACTCAATTTGCTGAGTTTGAACACGCTATTCATCAAGCAGACCAAAATGGGGAAGTCTTGACAAGCGATTTC
CTAAATAAACTCTACGCAGACTTGAACCAAGAATATTATGGTTTGAGTAAGGAAGACAATCCTGAAATCCAATACGAGTG
GGCTCGCATTCCACACTTCTACTATAACTACTATGTATACCAATATTCAACAGGTTTTGCAGCAGCCTCAGCTTTGGCTG
AAAAAATTGTCCATGGTAGTCAAGAAGACCGTGACCGCTATATCGACTACCTCAAGGCAGGTAAGTCTGACTATCCACTT
AATGTCATGAGAAAAGCTGGTGTTGATATGGAGAAGGAAGACTATCTCAACGATGCCTTTGCAGTCTTTGAACGTCGTTT
GAATGAGTTTGAAGCCCTTGTTGAAAAATTGGGATTGGCATAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(202-581)

Oligopeptidase F (Peptidase_M3_N)

(112-181)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

67.45

99.333

0.67

Multiple sequence alignment