Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   ACLV7H_RS07010 Genome accession   NZ_OZ217340
Coordinates   1339727..1341985 (+) Length   752 a.a.
NCBI ID   WP_411866742.1    Uniprot ID   -
Organism   Streptococcus oralis isolate S. oralis A22     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1334727..1346985
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7H_RS06980 (SORA22_14040) - 1335515..1336288 (-) 774 WP_045590826.1 HAD hydrolase family protein -
  ACLV7H_RS06985 (SORA22_14050) - 1336293..1337150 (-) 858 WP_045590825.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  ACLV7H_RS06990 (SORA22_14060) - 1337299..1337619 (-) 321 WP_411866741.1 TfoX/Sxy family protein -
  ACLV7H_RS06995 (SORA22_14070) - 1337652..1338386 (-) 735 WP_000140925.1 amino acid ABC transporter ATP-binding protein -
  ACLV7H_RS07000 (SORA22_14080) - 1338386..1339069 (-) 684 WP_045590822.1 amino acid ABC transporter permease -
  ACLV7H_RS07005 (SORA22_14090) - 1339260..1339490 (+) 231 WP_000443579.1 DUF1797 family protein -
  ACLV7H_RS07010 (SORA22_14110) clpE 1339727..1341985 (+) 2259 WP_411866742.1 AAA family ATPase Regulator
  ACLV7H_RS07015 (SORA22_14120) - 1342117..1342569 (+) 453 WP_045590819.1 NUDIX hydrolase -
  ACLV7H_RS07020 (SORA22_14130) - 1342628..1342927 (+) 300 WP_000767203.1 DUF1827 family protein -
  ACLV7H_RS07025 (SORA22_14140) metK 1342995..1344185 (-) 1191 WP_411866743.1 methionine adenosyltransferase -
  ACLV7H_RS07030 (SORA22_14150) - 1344529..1345872 (-) 1344 WP_045590813.1 DEAD/DEAH box helicase -
  ACLV7H_RS07035 (SORA22_14160) - 1346004..1346819 (-) 816 WP_045590812.1 endonuclease/exonuclease/phosphatase family protein -

Sequence

Protein


Download         Length: 752 a.a.        Molecular weight: 83901.37 Da        Isoelectric Point: 5.1262

>NTDB_id=1169968 ACLV7H_RS07010 WP_411866742.1 1339727..1341985(+) (clpE) [Streptococcus oralis isolate S. oralis A22]
MLCQNCKINDSTIHLYTNLNGQQKQIDLCQNCYKIIKTDPNNTLFKGMTDLNNRDFDPFGDFFNDLNNFKPSTNNVPPTQ
SGGGYGGNGGYGPQNRGPLQTPPSQERGLLEEYGINITEIARRGDIDPVIGRDEEIIRVIEILNRRTKNNPVLIGEPGVG
KTAVVECLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKREDIILFIDEIHEIVGAGSAGDG
NMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETIIILKGVQKKYEDYHHVKYTDAAIEA
AANLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKAQATREEDFEKAAYFRDQIAKYKEMQKN
KVTDQDTPIISEKTIEHIIEQKTNIPVGELKEKEQSQLIHLADDLKAHVIGQDEAVDKIAKAIRRNRVGLGTPNRPIGSF
LFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDEVEK
AHPDVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKAEASVGFGAAREGRTNSVLGELGNFFSPEFMNRFDGI
IEFKPLSKDNLLQIVELMLADVNKRLSSNNIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDFYLENPSEK
ALKAVMTSNGNIQIKSAKKAEKTEEIASEKEE

Nucleotide


Download         Length: 2259 bp        

>NTDB_id=1169968 ACLV7H_RS07010 WP_411866742.1 1339727..1341985(+) (clpE) [Streptococcus oralis isolate S. oralis A22]
ATGCTCTGTCAAAACTGTAAAATTAACGACTCAACAATTCATCTGTATACCAATCTCAATGGACAGCAAAAACAAATTGA
TCTTTGTCAAAATTGCTATAAAATTATCAAAACAGATCCAAATAATACCCTCTTTAAAGGAATGACTGACTTAAACAATC
GTGACTTTGATCCTTTCGGAGACTTTTTCAATGATTTGAACAATTTCAAACCTTCTACTAATAACGTCCCTCCAACTCAA
TCTGGTGGCGGATACGGAGGAAACGGCGGTTATGGACCTCAAAACCGCGGTCCACTTCAAACACCTCCTAGCCAAGAAAG
AGGACTCTTAGAGGAATACGGTATCAATATTACTGAGATTGCTCGTCGGGGAGATATTGACCCTGTTATCGGTCGAGATG
AGGAGATTATCCGCGTTATCGAAATCCTCAACCGTCGAACCAAAAACAATCCTGTCCTTATCGGAGAACCAGGTGTTGGT
AAAACAGCTGTTGTTGAATGTCTAGCTCAGAAGATTGTCGATGGTGATGTTCCCCATAAACTCCAAGGCAAGCAGGTCAT
CCGTCTGGATGTGGTTAGTCTAGTTCAAGGAACAGGGATTCGAGGCCAATTTGAAGAACGCATGCAAAAGCTCATGGAAG
AAATTCGCAAACGCGAGGACATTATCCTCTTTATCGACGAAATCCATGAAATTGTTGGTGCAGGATCTGCTGGCGATGGC
AATATGGATGCAGGCAATATCCTGAAACCAGCCCTTGCCCGTGGTGAATTGCAACTGGTCGGCGCCACTACCCTCAATGA
ATACCGTATTATTGAAAAAGATGCTGCTCTCGAGCGCCGTATGCAGCCTGTCAAGGTAGATGAACCAACTGTCGAAGAAA
CTATTATCATCCTCAAAGGGGTTCAAAAGAAATACGAAGACTACCATCACGTCAAGTATACTGATGCGGCTATAGAAGCT
GCTGCAAATCTGTCCAATCGTTACATTCAAGACCGCTTCTTACCTGACAAGGCTATTGACCTTTTGGACGAAGCCGGTTC
TAAGATGAATCTGACGCTGAACTTTGTGGATCCCAAAGTGATTGACCAGCGTTTAATTGAGGCCGAGAATCTCAAGGCTC
AAGCTACACGAGAGGAAGACTTTGAAAAAGCTGCCTACTTCCGTGATCAGATTGCCAAGTACAAGGAAATGCAGAAAAAC
AAGGTGACCGATCAGGATACTCCAATCATCAGTGAGAAAACCATTGAACACATCATCGAGCAGAAAACCAATATTCCTGT
CGGAGAACTCAAAGAAAAAGAACAGTCTCAGCTTATCCATCTAGCAGACGACCTCAAAGCTCATGTCATTGGTCAAGATG
AAGCTGTCGATAAGATTGCCAAAGCCATCCGTCGTAATCGTGTTGGTCTTGGAACTCCTAACCGGCCAATCGGAAGTTTC
CTCTTTGTCGGACCAACTGGTGTCGGTAAGACAGAACTGTCCAAACAACTAGCCATTGAACTTTTTGGTTCTGCTGACAG
CATGATTCGCTTTGATATGAGTGAATACATGGAAAAACACAGTGTGGCTAAATTGGTCGGAGCCCCTCCAGGCTATGTAG
GCTATGATGAAGCTGGTCAGTTAACGGAAAAAGTTCGCCGTAATCCCTACTCTCTCATCCTTCTCGATGAAGTGGAAAAA
GCTCACCCTGATGTCATGCACATGTTCCTTCAAGTCTTGGACGATGGTCGTTTGACAGATGGGCAAGGACGGACAGTTAG
CTTTAAGGATGCTATCATTATTATGACCTCAAATGCCGGTACGGGTAAGGCCGAAGCCAGTGTTGGGTTTGGAGCTGCTC
GTGAAGGACGTACTAATTCTGTTCTTGGTGAACTCGGTAACTTCTTTAGTCCTGAGTTTATGAACCGTTTTGACGGCATC
ATCGAATTTAAACCTCTCAGCAAGGACAACCTTCTCCAAATCGTCGAACTCATGCTAGCGGATGTCAACAAACGCCTCTC
TAGCAACAATATCCACCTCGATGTGACAGACAAGGTCAAGGAAAAATTGGTTGACTTGGGATATGATCCAAAAATGGGGG
CACGCCCACTTCGCCGTACCATTCAAGATCATATCGAGGATGCTATCACAGACTTCTACCTTGAAAATCCAAGTGAGAAA
GCCCTCAAAGCAGTCATGACAAGCAATGGCAATATTCAAATCAAATCTGCCAAAAAAGCTGAGAAAACAGAAGAGATTGC
TTCTGAAAAAGAAGAATAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(475-638)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(646-721)

AAA lid domain (AAA_lid_9)

(290-387)

ATPase family associated with various cellular activities (AAA) (AAA)

(152-271)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

93.907

100

0.943
  clpE Streptococcus pneumoniae D39

93.907

100

0.943
  clpE Streptococcus pneumoniae R6

93.907

100

0.943
  clpE Streptococcus pneumoniae TIGR4

93.775

100

0.941
  clpE Streptococcus mutans UA159

83.156

100

0.834
  clpC Lactococcus lactis subsp. cremoris KW2

76.064

100

0.761
  clpC Bacillus subtilis subsp. subtilis str. 168

52.388

86.303

0.452
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.737

87.633

0.41
  clpC Streptococcus thermophilus LMD-9

46.593

83.91

0.391
  clpC Streptococcus pneumoniae Rx1

47.021

82.58

0.388
  clpC Streptococcus pneumoniae D39

47.021

82.58

0.388
  clpC Streptococcus pneumoniae TIGR4

47.021

82.58

0.388
  clpC Streptococcus thermophilus LMG 18311

46.349

83.777

0.388
  clpC Streptococcus mutans UA159

46.349

83.777

0.388

Multiple sequence alignment