Detailed information NTG0116991

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: RG49_RS14455
• Genome accession: NZ_CP010171
• Coordinates: 2664845..2665870 (+)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli strain H7
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 2659845..2670870

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RG49_RS14435 (RG49_13365)	metJ	2660906..2661223 (+)	318	WP_000852812.1	met regulon transcriptional regulator MetJ	-
RG49_RS14440 (RG49_13370)	yiiX	2661407..2662015 (+)	609	WP_000797353.1	YiiX family permuted papain-like enzyme	-
RG49_RS14445 (RG49_13375)	rpmE	2662076..2662288 (-)	213	WP_000710769.1	50S ribosomal protein L31	-
RG49_RS14450 (RG49_13380)	priA	2662491..2664689 (+)	2199	WP_001301269.1	primosomal protein N'	Machinery gene
RG49_RS14455 (RG49_13385)	cytR	2664845..2665870 (+)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
RG49_RS14460 (RG49_13390)	ftsN	2665962..2666921 (+)	960	WP_072135208.1	cell division protein FtsN	-
RG49_RS14465 (RG49_13395)	hslV	2667014..2667544 (+)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
RG49_RS14470 (RG49_13400)	hslU	2667554..2668885 (+)	1332	WP_001293341.1	HslU--HslV peptidase ATPase subunit	-
RG49_RS14475 (RG49_13405)	menA	2668952..2669878 (+)	927	WP_000139496.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
RG49_RS14480 (RG49_13410)	rraA	2669971..2670456 (+)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-
RG49_RS14485 (RG49_13415)	zapB	2670541..2670786 (-)	246	WP_001296623.1	septal ring assembly protein ZapB	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=116991 RG49_RS14455 WP_000644904.1 2664845..2665870(+) (cytR) [Escherichia coli strain H7]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=116991 RG49_RS14455 WP_000644904.1 2664845..2665870(+) (cytR) [Escherichia coli strain H7]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACCGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCGCAGCCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGATCCC
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGTTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAGCTGGAG
CTGCCTACAGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCGCTGTGTCACTACCGCCTGCAAGGCTATGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCGATGCAGCAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628