Detailed information    

insolico Bioinformatically predicted

Overview

Name   recD   Type   Machinery gene
Locus tag   ACH8EH_RS03725 Genome accession   NZ_OZ197914
Coordinates   714657..716402 (+) Length   581 a.a.
NCBI ID   WP_047920976.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae isolate SGC-24-002     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 679482..754283 714657..716402 within 0
IS/Tn 717089..718090 714657..716402 flank 687


Gene organization within MGE regions


Location: 679482..754283
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACH8EH_RS03550 - 679482..680552 (-) 1071 WP_003695318.1 integrase arm-type DNA-binding domain-containing protein -
  ACH8EH_RS03555 - 680761..681540 (-) 780 WP_003688701.1 ferredoxin--NADP reductase -
  ACH8EH_RS03560 - 681832..682128 (-) 297 WP_003688700.1 hypothetical protein -
  ACH8EH_RS03565 - 682132..682341 (-) 210 WP_003688699.1 hypothetical protein -
  ACH8EH_RS03570 dinB 682440..683498 (+) 1059 WP_041421282.1 DNA polymerase IV -
  ACH8EH_RS03575 rep 683568..685583 (-) 2016 WP_012503651.1 DNA helicase Rep -
  ACH8EH_RS03580 aroD 685603..686367 (-) 765 WP_003688696.1 type I 3-dehydroquinate dehydratase -
  ACH8EH_RS03585 recA 686567..687613 (+) 1047 WP_003688695.1 recombinase RecA Machinery gene
  ACH8EH_RS03590 - 688268..688603 (-) 336 WP_003688693.1 YbaB/EbfC family nucleoid-associated protein -
  ACH8EH_RS03595 dnaX 688684..690807 (-) 2124 WP_003691207.1 DNA polymerase III subunit gamma/tau -
  ACH8EH_RS03600 mutL 690902..692866 (-) 1965 WP_003697109.1 DNA mismatch repair endonuclease MutL -
  ACH8EH_RS03605 - 693010..693195 (+) 186 WP_003688687.1 DUF3460 family protein -
  ACH8EH_RS03610 - 693206..693874 (+) 669 WP_003688686.1 class I SAM-dependent methyltransferase -
  ACH8EH_RS03615 - 693874..694587 (+) 714 WP_003697104.1 tol-pal system YbgF family protein -
  ACH8EH_RS03620 purE 694635..695120 (+) 486 WP_003688684.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  ACH8EH_RS03625 - 695332..696197 (-) 866 Protein_713 transposase -
  ACH8EH_RS03630 - 696514..696879 (+) 366 Protein_714 transposase -
  ACH8EH_RS03635 - 696886..697911 (+) 1026 Protein_715 autotransporter outer membrane beta-barrel domain-containing protein -
  ACH8EH_RS03640 - 698106..698762 (-) 657 WP_003688682.1 response regulator transcription factor -
  ACH8EH_RS03645 - 698759..700528 (-) 1770 WP_003688681.1 histidine kinase -
  ACH8EH_RS03650 - 700735..701349 (+) 615 WP_003691204.1 molybdenum cofactor guanylyltransferase -
  ACH8EH_RS03655 - 701512..702129 (+) 618 WP_010358100.1 riboflavin synthase -
  ACH8EH_RS03660 - 702137..703000 (+) 864 WP_003688678.1 ATP-binding protein -
  ACH8EH_RS03665 - 703013..703447 (-) 435 WP_003688677.1 Spy/CpxP family protein refolding chaperone -
  ACH8EH_RS03670 rpe 703593..704276 (+) 684 WP_003688675.1 ribulose-phosphate 3-epimerase -
  ACH8EH_RS03675 ruvB 704521..705552 (-) 1032 WP_003691202.1 Holliday junction branch migration DNA helicase RuvB -
  ACH8EH_RS03680 - 705634..705942 (-) 309 WP_003688671.1 hypothetical protein -
  ACH8EH_RS03685 - 706361..707593 (-) 1233 WP_003688669.1 multifunctional CCA addition/repair protein -
  ACH8EH_RS03690 - 707672..709300 (-) 1629 WP_010951119.1 ABC-F family ATPase -
  ACH8EH_RS03695 - 709450..709824 (+) 375 WP_003688664.1 arsenate reductase -
  ACH8EH_RS03700 - 709873..711411 (+) 1539 WP_003695299.1 SurA N-terminal domain-containing protein -
  ACH8EH_RS03705 recR 711478..712095 (+) 618 WP_003688660.1 recombination mediator RecR -
  ACH8EH_RS03710 - 712151..712429 (-) 279 WP_003688659.1 hypothetical protein -
  ACH8EH_RS03715 - 712655..713902 (+) 1248 WP_003691197.1 lipoprotein-releasing ABC transporter permease subunit -
  ACH8EH_RS03720 lolD 713895..714590 (+) 696 WP_395373238.1 lipoprotein-releasing ABC transporter ATP-binding protein LolD -
  ACH8EH_RS03725 recD 714657..716402 (+) 1746 WP_047920976.1 exodeoxyribonuclease V subunit alpha Machinery gene
  ACH8EH_RS03730 - 716474..717120 (-) 647 Protein_734 methyltransferase -
  ACH8EH_RS03735 - 717128..718090 (+) 963 WP_050303398.1 IS110 family transposase -
  ACH8EH_RS03740 - 718219..718678 (-) 460 Protein_736 methyltransferase -
  ACH8EH_RS03745 lon 718930..721392 (+) 2463 WP_003691187.1 endopeptidase La -
  ACH8EH_RS03750 - 721574..721843 (+) 270 WP_003688640.1 HU family DNA-binding protein -
  ACH8EH_RS03755 - 722019..722453 (-) 435 WP_003688638.1 hypothetical protein -
  ACH8EH_RS03760 - 722446..723753 (-) 1308 WP_003702721.1 homoserine dehydrogenase -
  ACH8EH_RS03765 - 723949..724320 (+) 372 WP_003688636.1 Mth938-like domain-containing protein -
  ACH8EH_RS03770 - 724397..726319 (+) 1923 WP_047922588.1 ATP-binding cassette domain-containing protein -
  ACH8EH_RS03775 - 726306..726701 (+) 396 WP_010358122.1 hypothetical protein -
  ACH8EH_RS03780 - 726792..727304 (+) 513 WP_395373245.1 hypothetical protein -
  ACH8EH_RS03785 - 727749..728444 (-) 696 WP_041421278.1 DUF4400 domain-containing protein -
  ACH8EH_RS03790 traD 728434..730476 (-) 2043 WP_012503640.1 type IV conjugative transfer system coupling protein TraD -
  ACH8EH_RS03795 mobH 730473..733025 (-) 2553 WP_012503639.1 MobH family relaxase -
  ACH8EH_RS03800 - 733022..733441 (-) 420 WP_003693104.1 hypothetical protein -
  ACH8EH_RS03805 - 733953..734414 (+) 462 WP_012503638.1 lytic transglycosylase domain-containing protein -
  ACH8EH_RS03810 - 734384..734905 (+) 522 WP_395373251.1 OmpA family protein -
  ACH8EH_RS03815 traA 734961..735257 (+) 297 WP_003697092.1 TraA family conjugative transfer protein -
  ACH8EH_RS03820 traL 735279..735560 (+) 282 WP_003693110.1 type IV conjugative transfer system protein TraL -
  ACH8EH_RS03825 - 735557..736222 (+) 666 WP_003704028.1 conjugal transfer protein TraE -
  ACH8EH_RS03830 - 736224..736958 (+) 735 WP_003693114.1 type-F conjugative transfer system secretin TraK -
  ACH8EH_RS03835 - 736960..738273 (+) 1314 WP_003697090.1 TrbI/VirB10 family protein -
  ACH8EH_RS03840 - 738283..739002 (+) 720 WP_003693119.1 DsbC family protein -
  ACH8EH_RS03845 - 739002..739580 (+) 579 WP_229690052.1 TraV family lipoprotein -
  ACH8EH_RS03850 - 739590..741902 (+) 2313 WP_395373258.1 TraC family protein -
  ACH8EH_RS03855 - 741930..742478 (+) 549 WP_003695274.1 hypothetical protein -
  ACH8EH_RS03860 - 742478..743023 (+) 546 WP_003704029.1 S26 family signal peptidase -
  ACH8EH_RS03865 - 743032..743688 (+) 657 WP_003693128.1 hypothetical protein -
  ACH8EH_RS03870 - 743685..744803 (+) 1119 WP_003695266.1 TraU family protein -
  ACH8EH_RS03875 - 744830..745003 (-) 174 WP_228369789.1 hypothetical protein -
  ACH8EH_RS03880 trbC 745088..745570 (+) 483 WP_228369788.1 type-F conjugative transfer system pilin assembly protein TrbC -
  ACH8EH_RS03885 - 745567..746811 (+) 1245 WP_003695263.1 hypothetical protein -
  ACH8EH_RS03890 traN 746850..748391 (+) 1542 WP_226876101.1 conjugal transfer protein TraN -
  ACH8EH_RS03895 - 748378..748803 (+) 426 WP_003693140.1 hypothetical protein -
  ACH8EH_RS03900 - 748815..749591 (+) 777 WP_012503632.1 thioredoxin family protein -
  ACH8EH_RS03905 - 749763..751274 (+) 1512 WP_041421275.1 conjugal transfer protein TraH -
  ACH8EH_RS03910 - 751281..754283 (+) 3003 WP_012503630.1 conjugal transfer protein TraG N-terminal domain-containing protein -

Sequence

Protein


Download         Length: 581 a.a.        Molecular weight: 63113.87 Da        Isoelectric Point: 5.8825

>NTDB_id=1169763 ACH8EH_RS03725 WP_047920976.1 714657..716402(+) (recD) [Neisseria gonorrhoeae isolate SGC-24-002]
MELQTDEFAQAAARAAIRFLERYAGSGNEVLANCTERLFQALQNGHSFIRLSGDEADALSALAPVVGTSAAPLILEGRRL
FLGRMWQLEYDLAAEIKRLAAAGTSAPDAAGARQNLAKWFQGAGSEGQRDAAALALLQFFMVITGGPGTGKTTTVAKLLA
LICGENENLPHIALAAPTGKAAAHMARALHRSINGFDAPEAVRRHLLKLEGQTVHRLLKLSPPKMQAAFDHIRPLPFDVL
IVDEASMLDTALMLQLLKAVKTGARVILLGDENQLPSVGIGAVLSVLSQKTVLDGETHQRLAGFLPEHGFSVSANPPVLA
QNTAHLSFSHRFGDNSGIGCLARAAVSGDEGAWALFDRFPDELEHSECSPNARVERLYRAHKAYWQAVKDGNIEAAYAGI
SDIVVLAAWRQDAEDFNEAYCSYVRRKMNIPEHLAYFAGEPIMIRQNDYALELFNGDIGLIMEDVGRQGSLAAYFADADG
FKKVAVSCLPEFEPAFAMTVHKSQGSEYREVWLLPPSDAPSDEGDDALSGLSKELLYTAITRAREKFVFFGGKKTFCQAV
NTVKVRQTALDSMLERVFSQE

Nucleotide


Download         Length: 1746 bp        

>NTDB_id=1169763 ACH8EH_RS03725 WP_047920976.1 714657..716402(+) (recD) [Neisseria gonorrhoeae isolate SGC-24-002]
ATGGAACTGCAGACAGATGAATTTGCCCAAGCGGCGGCAAGGGCGGCAATCCGTTTTTTGGAACGCTATGCGGGTTCGGG
CAACGAAGTGCTTGCAAACTGTACCGAACGCCTGTTTCAGGCATTGCAAAACGGTCATTCGTTTATCCGTTTGAGCGGGG
ACGAGGCTGACGCGCTGTCGGCACTCGCACCCGTGGTCGGAACATCCGCCGCGCCTTTGATTTTGGAAGGCAGAAGGCTG
TTTTTGGGCAGGATGTGGCAGTTGGAATACGATTTGGCTGCCGAAATAAAACGCTTGGCGGCAGCCGGCACGTCCGCCCC
CGACGCGGCAGGCGCGCGGCAAAACCTCGCAAAATGGTTTCAAGGCGCGGGAAGCGAAGGACAGCGCGATGCGGCCGCCT
TGGCACTGTTGCAGTTTTTTATGGTGATTACCGGAGGGCCGGGAACGGGCAAAACGACAACGGTTGCCAAACTGCTGGCA
CTGATTTGCGGTGAAAACGAAAATCTTCCCCATATCGCGCTTGCCGCACCGACGGGCAAAGCGGCGGCACATATGGCGCG
CGCGCTGCACCGTTCAATCAACGGTTTTGACGCGCCGGAGGCCGTCCGCCGCCATTTGCTCAAACTGGAAGGGCAAACCG
TCCACCGACTGCTTAAGCTGAGCCCGCCCAAAATGCAGGCGGCGTTCGACCATATCCGTCCGCTGCCGTTCGACGTGCTG
ATTGTCGATGAAGCCTCCATGTTGGATACCGCATTGATGCTGCAACTTTTGAAAGCGGTCAAAACCGGCGCGCGCGTGAT
TCTGCTGGGCGATGAAAACCAGCTCCCGTCCGTCGGAATCGGGGCGGTGCTGTCCGTTTTGTCGCAAAAAACCGTTTTGG
ACGGAGAAACGCACCAAAGGCTGGCCGGTTTCCTTCCGGAACACGGTTTCAGCGTCAGCGCAAATCCGCCCGTGTTGGCG
CAAAACACCGCCCATCTGTCGTTCAGCCACCGCTTCGGCGACAACAGCGGCATCGGCTGCCTTGCCCGTGCCGCCGTATC
GGGCGATGAAGGGGCGTGGGCATTGTTTGACCGGTTTCCGGACGAACTGGAACATTCGGAATGCAGTCCGAATGCTCGGG
TCGAAAGGTTGTACCGGGCGCACAAAGCCTATTGGCAGGCGGTAAAAGACGGCAATATCGAAGCCGCATACGCAGGTATC
TCGGATATCGTGGTTCTGGCAGCTTGGCGGCAGGATGCGGAAGACTTCAACGAAGCCTATTGCAGCTATGTACGCCGCAA
AATGAACATACCGGAACATTTGGCCTATTTCGCCGGAGAGCCGATTATGATCAGACAGAACGACTACGCGCTTGAGCTGT
TCAACGGCGACATCGGACTGATTATGGAAGATGTCGGACGGCAGGGCAGCCTTGCCGCCTATTTTGCCGATGCGGACGGA
TTTAAAAAGGTAGCGGTAAGCTGCCTGCCCGAATTTGAACCCGCATTCGCCATGACCGTCCACAAAAGCCAAGGTTCGGA
ATATCGGGAAGTCTGGCTGCTGCCGCCTTCCGACGCACCTTCGGACGAAGGGGACGATGCATTGTCCGGATTGAGTAAGG
AGCTGTTATATACCGCCATTACCCGCGCCAGGGAAAAATTCGTATTTTTCGGCGGCAAAAAGACATTTTGTCAGGCGGTA
AACACCGTCAAAGTCCGTCAGACGGCGTTGGACAGTATGCTTGAGCGGGTATTTTCACAAGAATAA

Domains

Predicted by InterproScan.

UvrD-like helicase C-terminal domain (UvrD_C_2)

(494-548)

AAA domain (AAA_30)

(125-290)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recD Neisseria gonorrhoeae strain FA1090

99.828

100

0.998

Multiple sequence alignment