Detailed information NTG1169677

Bioinformatically predicted

Overview

• Name: comGA
• Type: Machinery gene
• Locus tag: ACNUD0_RS10860
• Genome accession: NZ_OZ197102
• Coordinates: 2134850..2135824 (+)
• Length: 324 a.a.
• NCBI ID: WP_000697220.1
• Uniprot ID: W8U5L8
• Organism: Staphylococcus aureus isolate 23S01975-1
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2129850..2140824

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACNUD0_RS10825	rpmG	2130310..2130459 (+)	150	WP_001265709.1	50S ribosomal protein L33	-
ACNUD0_RS10830	-	2130668..2131207 (+)	540	WP_000164554.1	5-formyltetrahydrofolate cyclo-ligase	-
ACNUD0_RS10835	-	2131219..2132682 (+)	1464	WP_001017856.1	rhomboid family protein	-
ACNUD0_RS10840	-	2132663..2132866 (+)	204	WP_000087559.1	YqgQ family protein	-
ACNUD0_RS10845	-	2132863..2133849 (+)	987	WP_000161315.1	ROK family glucokinase	-
ACNUD0_RS10850	-	2133849..2134178 (+)	330	WP_001018871.1	MTH1187 family thiamine-binding protein	-
ACNUD0_RS10855	-	2134175..2134798 (+)	624	WP_001223008.1	MBL fold metallo-hydrolase	-
ACNUD0_RS10860	comGA	2134850..2135824 (+)	975	WP_000697220.1	competence type IV pilus ATPase ComGA	Machinery gene
ACNUD0_RS10865	comGB	2135796..2136866 (+)	1071	WP_000776425.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACNUD0_RS10870	-	2137013..2138184 (+)	1172	Protein_2095	IS256-like element IS256 family transposase	-
ACNUD0_RS10875	-	2138251..2138397 (+)	147	WP_001789879.1	hypothetical protein	-
ACNUD0_RS10880	-	2138387..2138911 (+)	525	WP_001015120.1	shikimate kinase	-
ACNUD0_RS10885	gcvT	2139070..2140161 (+)	1092	WP_000093349.1	glycine cleavage system aminomethyltransferase GcvT	-

Sequence

Protein

• Length: 324 a.a.
• Molecular weight: 36897.96 Da
• Isoelectric Point: 8.8516

>NTDB_id=1169677 ACNUD0_RS10860 WP_000697220.1 2134850..2135824(+) (comGA) [Staphylococcus aureus isolate 23S01975-1]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide

• Length: 975 bp

>NTDB_id=1169677 ACNUD0_RS10860 WP_000697220.1 2134850..2135824(+) (comGA) [Staphylococcus aureus isolate 23S01975-1]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTACGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGGCCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATTGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (7-267)

3D structure

• AlphaFold DB: W8U5L8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA	Staphylococcus aureus MW2	100	100	1
comGA	Staphylococcus aureus N315	100	100	1