Detailed information NTG1169660

Bioinformatically predicted

Overview

• Name: ccrA
• Type: Machinery gene
• Locus tag: ACNUD0_RS04825
• Genome accession: NZ_OZ197102
• Coordinates: 936021..937370 (-)
• Length: 449 a.a.
• NCBI ID: WP_031775881.1
• Uniprot ID: -
• Organism: Staphylococcus aureus isolate 23S01975-1
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	927606..942922	936021..937370	within	0

Gene organization within MGE regions

Location: 927606..942922

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACNUD0_RS04785	mecA	927606..929615 (-)	2010	WP_001801873.1	PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA	-
ACNUD0_RS04790	-	929712..930698 (+)	987	WP_001549960.1	beta-lactam sensor/signal transducer MecR1	-
ACNUD0_RS04795	-	930688..930930 (+)	243	Protein_903	type I restriction enzyme endonuclease domain-containing protein	-
ACNUD0_RS04800	-	930921..932531 (-)	1611	Protein_904	IS1182 family transposase	-
ACNUD0_RS04805	-	932580..933086 (-)	507	WP_001092189.1	DUF1643 domain-containing protein	-
ACNUD0_RS04810	-	933101..933412 (-)	312	WP_000700851.1	DUF960 family protein	-
ACNUD0_RS04815	-	933499..933849 (-)	351	WP_000849672.1	SAUGI family uracil-DNA glycosylase inhibitor	-
ACNUD0_RS04820	ccrB	934371..935999 (-)	1629	WP_001186604.1	cassette chromosome recombinase CcrB	Machinery gene
ACNUD0_RS04825	ccrA	936021..937370 (-)	1350	WP_031775881.1	cassette chromosome recombinase CcrA	Machinery gene
ACNUD0_RS04830	cch1	937604..939391 (-)	1788	WP_000122621.1	cassette chromosome replicative helicase	-
ACNUD0_RS04835	ssb	939391..939681 (-)	291	WP_001036437.1	cassette chromosome ssDNA-binding protein	-
ACNUD0_RS04840	-	939820..940869 (+)	1050	WP_000613248.1	hypothetical protein	-
ACNUD0_RS04845	-	941432..942922 (+)	1491	WP_000554504.1	RNA-binding domain-containing protein	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 52635.34 Da
• Isoelectric Point: 10.0472

>NTDB_id=1169660 ACNUD0_RS04825 WP_031775881.1 936021..937370(-) (ccrA) [Staphylococcus aureus isolate 23S01975-1]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYRVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYDYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRLQKQTKQTSSDNQLKQKIKCPCCNATLTNMTIRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKGAIDKRIKRQRNIEKHHILTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQRTIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQAMQSSIA

Nucleotide

• Length: 1350 bp

>NTDB_id=1169660 ACNUD0_RS04825 WP_031775881.1 936021..937370(-) (ccrA) [Staphylococcus aureus isolate 23S01975-1]
ATGAAACAAGTTATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACACAATTAATTCAACAAGGACAATGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
TTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACATATCGTGTTCATATCTTAAGTGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCGGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACCCATGCGCCCTTTGGTTACGATTATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGTCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATTGCAAAAACAAACCAAACAGACATCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCATTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAGGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACATATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATAAATGGGCATCAAATACAACGCACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAGCCATGCAATCATCGATTGCATAA

Domains

Predicted by InterproScan.

• Recombinase (Recombinase) (169-248)

• Recombinase zinc beta ribbon domain (Zn_ribbon_recom) (262-321)

• Resolvase, N terminal domain (Resolvase) (4-147)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrA	Staphylococcus aureus N315	97.327	100	0.973
ccrA	Staphylococcus aureus COL	74.833	100	0.748