Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACNUDU_RS06300 Genome accession   NZ_OZ197099
Coordinates   1273600..1274316 (-) Length   238 a.a.
NCBI ID   WP_064137750.1    Uniprot ID   -
Organism   Staphylococcus aureus isolate 23S00079-1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1268600..1279316
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACNUDU_RS06285 - 1269689..1270639 (+) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -
  ACNUDU_RS06290 - 1270788..1272272 (+) 1485 WP_000141407.1 sucrose-6-phosphate hydrolase -
  ACNUDU_RS06295 - 1272269..1273228 (+) 960 WP_001253294.1 carbohydrate kinase family protein -
  ACNUDU_RS06300 agrA 1273600..1274316 (-) 717 WP_064137750.1 quorum-sensing response regulator AgrA Regulator
  ACNUDU_RS06305 agrC 1274335..1275627 (-) 1293 WP_001825886.1 quorum-sensing sensor histidine kinase AgrC -
  ACNUDU_RS06310 agrD 1275652..1275792 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  ACNUDU_RS06315 agrB 1275789..1276358 (-) 570 WP_001105708.1 accessory gene regulator AgrB -
  ACNUDU_RS06320 hld 1276648..1276728 (+) 81 WP_000046022.1 delta-hemolysin -
  ACNUDU_RS06325 - 1277329..1278114 (-) 786 WP_000867947.1 carbon-nitrogen family hydrolase -
  ACNUDU_RS06330 - 1278422..1279048 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27965.94 Da        Isoelectric Point: 6.0935

>NTDB_id=1169552 ACNUDU_RS06300 WP_064137750.1 1273600..1274316(-) (agrA) [Staphylococcus aureus isolate 23S00079-1]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGYYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1169552 ACNUDU_RS06300 WP_064137750.1 1273600..1274316(-) (agrA) [Staphylococcus aureus isolate 23S00079-1]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTATTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment