Detailed information NTG1169531

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACNUD2_RS09245
• Genome accession: NZ_OZ197097
• Coordinates: 1770869..1771912 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus isolate 23S01471-1
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1765869..1776912

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACNUD2_RS09215	-	1766290..1767546 (-)	1257	WP_074347694.1	aminopeptidase	-
ACNUD2_RS09220	-	1767549..1767749 (-)	201	WP_000180460.1	DUF1128 family protein	-
ACNUD2_RS09225	-	1767896..1768360 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
ACNUD2_RS09230	-	1768367..1768642 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ACNUD2_RS09235	-	1768920..1770137 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
ACNUD2_RS09240	vraR	1770250..1770879 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
ACNUD2_RS09245	vraS	1770869..1771912 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACNUD2_RS09250	liaF	1771909..1772610 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACNUD2_RS09255	-	1772625..1773011 (-)	387	WP_001110182.1	hypothetical protein	-
ACNUD2_RS09260	map	1773228..1773986 (-)	759	WP_000636145.1	type I methionyl aminopeptidase	-
ACNUD2_RS09265	-	1774570..1775556 (+)	987	WP_000999712.1	FUSC family protein	-
ACNUD2_RS09270	-	1775745..1776158 (-)	414	WP_025174370.1	hypothetical protein	-
ACNUD2_RS09275	-	1776187..1776297 (-)	111	WP_014937049.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1169531 ACNUD2_RS09245 WP_001017131.1 1770869..1771912(-) (vraS) [Staphylococcus aureus isolate 23S01471-1]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1169531 ACNUD2_RS09245 WP_001017131.1 1770869..1771912(-) (vraS) [Staphylococcus aureus isolate 23S01471-1]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTTCTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAATTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAATTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1