Detailed information NTG1169516

Bioinformatically predicted

Overview

• Name: comGA
• Type: Machinery gene
• Locus tag: ACNUD2_RS04740
• Genome accession: NZ_OZ197097
• Coordinates: 904762..905736 (+)
• Length: 324 a.a.
• NCBI ID: WP_000697220.1
• Uniprot ID: W8U5L8
• Organism: Staphylococcus aureus isolate 23S01471-1
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 899762..910736

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACNUD2_RS04705	rpmG	900222..900371 (+)	150	WP_001265709.1	50S ribosomal protein L33	-
ACNUD2_RS04710	-	900580..901119 (+)	540	WP_000164554.1	5-formyltetrahydrofolate cyclo-ligase	-
ACNUD2_RS04715	-	901131..902594 (+)	1464	WP_001017856.1	rhomboid family protein	-
ACNUD2_RS04720	-	902575..902778 (+)	204	WP_000087559.1	YqgQ family protein	-
ACNUD2_RS04725	-	902775..903761 (+)	987	WP_000161315.1	ROK family glucokinase	-
ACNUD2_RS04730	-	903761..904090 (+)	330	WP_001018871.1	MTH1187 family thiamine-binding protein	-
ACNUD2_RS04735	-	904087..904710 (+)	624	WP_001223008.1	MBL fold metallo-hydrolase	-
ACNUD2_RS04740	comGA	904762..905736 (+)	975	WP_000697220.1	competence type IV pilus ATPase ComGA	Machinery gene
ACNUD2_RS04745	comGB	905708..906778 (+)	1071	WP_000776425.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACNUD2_RS04750	-	906925..908096 (+)	1172	Protein_926	IS256-like element IS256 family transposase	-
ACNUD2_RS04755	-	908163..908309 (+)	147	WP_001789879.1	hypothetical protein	-
ACNUD2_RS04760	-	908299..908823 (+)	525	WP_001015120.1	shikimate kinase	-
ACNUD2_RS04765	gcvT	908982..910073 (+)	1092	WP_000093349.1	glycine cleavage system aminomethyltransferase GcvT	-

Sequence

Protein

• Length: 324 a.a.
• Molecular weight: 36897.96 Da
• Isoelectric Point: 8.8516

>NTDB_id=1169516 ACNUD2_RS04740 WP_000697220.1 904762..905736(+) (comGA) [Staphylococcus aureus isolate 23S01471-1]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide

• Length: 975 bp

>NTDB_id=1169516 ACNUD2_RS04740 WP_000697220.1 904762..905736(+) (comGA) [Staphylococcus aureus isolate 23S01471-1]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTACGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGGCCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATTGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (7-267)

3D structure

• AlphaFold DB: W8U5L8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA	Staphylococcus aureus MW2	100	100	1
comGA	Staphylococcus aureus N315	100	100	1