Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   ACNUD1_RS10970 Genome accession   NZ_OZ197094
Coordinates   2147477..2148826 (+) Length   449 a.a.
NCBI ID   WP_416763906.1    Uniprot ID   -
Organism   Staphylococcus aureus isolate 23S00076-1     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 2141870..2157241 2147477..2148826 within 0


Gene organization within MGE regions


Location: 2141870..2157241
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACNUD1_RS10950 - 2141870..2143360 (-) 1491 WP_000554504.1 RNA-binding domain-containing protein -
  ACNUD1_RS10955 - 2143978..2145027 (-) 1050 WP_000613248.1 hypothetical protein -
  ACNUD1_RS10960 ssb 2145166..2145456 (+) 291 WP_001036437.1 cassette chromosome ssDNA-binding protein -
  ACNUD1_RS10965 cch1 2145456..2147243 (+) 1788 WP_000122621.1 cassette chromosome replicative helicase -
  ACNUD1_RS10970 ccrA 2147477..2148826 (+) 1350 WP_416763906.1 cassette chromosome recombinase CcrA Machinery gene
  ACNUD1_RS10975 ccrB 2148848..2150476 (+) 1629 WP_001186604.1 cassette chromosome recombinase CcrB Machinery gene
  ACNUD1_RS10980 - 2150998..2151348 (+) 351 WP_000849672.1 SAUGI family uracil-DNA glycosylase inhibitor -
  ACNUD1_RS10985 - 2151435..2151746 (+) 312 WP_000700851.1 DUF960 family protein -
  ACNUD1_RS10990 - 2151761..2152267 (+) 507 WP_001092189.1 DUF1643 domain-containing protein -
  ACNUD1_RS10995 - 2152316..2153926 (+) 1611 Protein_2132 IS1182 family transposase -
  ACNUD1_RS11000 - 2153917..2154159 (-) 243 Protein_2133 type I restriction enzyme endonuclease domain-containing protein -
  ACNUD1_RS11005 - 2154149..2155135 (-) 987 WP_001549960.1 beta-lactam sensor/signal transducer MecR1 -
  ACNUD1_RS11010 mecA 2155232..2157241 (+) 2010 WP_001801873.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52649.37 Da        Isoelectric Point: 10.0472

>NTDB_id=1169412 ACNUD1_RS10970 WP_416763906.1 2147477..2148826(+) (ccrA) [Staphylococcus aureus isolate 23S00076-1]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYRVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYDYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRLQKQTKQTSSDNQLKQKIKCPCCNATLTNMTIRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKGAIDKRIKRQRNIEKHHILTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQRTIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIINQAMQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1169412 ACNUD1_RS10970 WP_416763906.1 2147477..2148826(+) (ccrA) [Staphylococcus aureus isolate 23S00076-1]
ATGAAACAAGTTATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACACAATTAATTCAACAAGGACAATGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
TTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACATATCGTGTTCATATCTTAAGTGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCGGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACCCATGCGCCCTTTGGTTACGATTATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGTCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATTGCAAAAACAAACCAAACAGACATCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCATTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAGGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACATATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATAAATGGGCATCAAATACAACGCACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCATCAATCAAGCCATGCAATCATCGATTGCATAA

Domains

Predicted by InterproScan.

Recombinase (Recombinase)

(169-248)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-321)

Resolvase, N terminal domain (Resolvase)

(4-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus N315

97.105

100

0.971
  ccrA Staphylococcus aureus COL

74.61

100

0.746

Multiple sequence alignment