Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACNUEA_RS14010 Genome accession   NZ_OZ197093
Coordinates   2792555..2793271 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus isolate 23S01465-3     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2787555..2798271
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACNUEA_RS13995 - 2788644..2789594 (+) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -
  ACNUEA_RS14000 - 2789743..2791227 (+) 1485 WP_000141407.1 sucrose-6-phosphate hydrolase -
  ACNUEA_RS14005 - 2791224..2792183 (+) 960 WP_001253294.1 carbohydrate kinase family protein -
  ACNUEA_RS14010 agrA 2792555..2793271 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  ACNUEA_RS14015 agrC 2793290..2794582 (-) 1293 WP_001825886.1 quorum-sensing sensor histidine kinase AgrC -
  ACNUEA_RS14020 agrD 2794607..2794747 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  ACNUEA_RS14025 agrB 2794744..2795313 (-) 570 WP_001105708.1 accessory gene regulator AgrB -
  ACNUEA_RS14030 hld 2795603..2795683 (+) 81 WP_000046022.1 delta-hemolysin -
  ACNUEA_RS14035 - 2796284..2797069 (-) 786 WP_000867947.1 carbon-nitrogen family hydrolase -
  ACNUEA_RS14040 - 2797377..2798003 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1169378 ACNUEA_RS14010 WP_000688492.1 2792555..2793271(-) (agrA) [Staphylococcus aureus isolate 23S01465-3]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1169378 ACNUEA_RS14010 WP_000688492.1 2792555..2793271(-) (agrA) [Staphylococcus aureus isolate 23S01465-3]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment