Detailed information NTG1169374

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACNUEA_RS10855
• Genome accession: NZ_OZ197093
• Coordinates: 2172972..2173859 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus isolate 23S01465-3
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2167972..2178859

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACNUEA_RS10825	-	2168704..2169465 (+)	762	WP_000323448.1	alpha/beta hydrolase	-
ACNUEA_RS10830	-	2169710..2170165 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACNUEA_RS10835	-	2170287..2170388 (+)	102	WP_000731972.1	SE2200 family small protein	-
ACNUEA_RS10840	-	2170448..2171872 (-)	1425	WP_000953736.1	alkaline phosphatase	-
ACNUEA_RS10845	-	2172070..2172270 (+)	201	WP_000604731.1	hypothetical protein	-
ACNUEA_RS10850	braR	2172296..2172961 (+)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACNUEA_RS10855	braS	2172972..2173859 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACNUEA_RS10860	-	2173967..2174722 (+)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
ACNUEA_RS10865	-	2174719..2176719 (+)	2001	WP_000776741.1	ABC transporter permease	-
ACNUEA_RS10870	-	2177386..2177499 (+)	114	WP_014937089.1	hypothetical protein	-
ACNUEA_RS10875	-	2177881..2178141 (+)	261	WP_014937088.1	hypothetical protein	-
ACNUEA_RS10880	-	2178151..2178648 (+)	498	WP_001065267.1	glutathione peroxidase	-
ACNUEA_RS10885	-	2178756..2178848 (-)	93	WP_031774855.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=1169374 ACNUEA_RS10855 WP_000143420.1 2172972..2173859(+) (braS) [Staphylococcus aureus isolate 23S01465-3]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1169374 ACNUEA_RS10855 WP_000143420.1 2172972..2173859(+) (braS) [Staphylococcus aureus isolate 23S01465-3]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTGGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993