Detailed information NTG1169242

Bioinformatically predicted

Overview

• Name: comGA
• Type: Machinery gene
• Locus tag: ACNUD4_RS13395
• Genome accession: NZ_OZ197090
• Coordinates: 2636605..2637579 (-)
• Length: 324 a.a.
• NCBI ID: WP_000697220.1
• Uniprot ID: W8U5L8
• Organism: Staphylococcus aureus isolate 23S01467-1
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2631605..2642579

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACNUD4_RS13365	gcvT	2632270..2633361 (-)	1092	WP_000093349.1	glycine cleavage system aminomethyltransferase GcvT	-
ACNUD4_RS13370	-	2633520..2634044 (-)	525	WP_001015120.1	shikimate kinase	-
ACNUD4_RS13375	-	2634034..2634180 (-)	147	WP_001789879.1	hypothetical protein	-
ACNUD4_RS13380	-	2634247..2634926 (-)	680	Protein_2594	IS256 family transposase	-
ACNUD4_RS13385	-	2634926..2635417 (-)	492	WP_001813974.1	IS256 family transposase	-
ACNUD4_RS13390	comGB	2635563..2636633 (-)	1071	WP_000776425.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACNUD4_RS13395	comGA	2636605..2637579 (-)	975	WP_000697220.1	competence type IV pilus ATPase ComGA	Machinery gene
ACNUD4_RS13400	-	2637631..2638254 (-)	624	WP_001223008.1	MBL fold metallo-hydrolase	-
ACNUD4_RS13405	-	2638251..2638580 (-)	330	WP_001018871.1	MTH1187 family thiamine-binding protein	-
ACNUD4_RS13410	-	2638580..2639566 (-)	987	WP_000161315.1	ROK family glucokinase	-
ACNUD4_RS13415	-	2639563..2639766 (-)	204	WP_000087559.1	YqgQ family protein	-
ACNUD4_RS13420	-	2639747..2641210 (-)	1464	WP_001017856.1	rhomboid family protein	-
ACNUD4_RS13425	-	2641222..2641761 (-)	540	WP_000164554.1	5-formyltetrahydrofolate cyclo-ligase	-
ACNUD4_RS13430	rpmG	2641970..2642119 (-)	150	WP_001265709.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 324 a.a.
• Molecular weight: 36897.96 Da
• Isoelectric Point: 8.8516

>NTDB_id=1169242 ACNUD4_RS13395 WP_000697220.1 2636605..2637579(-) (comGA) [Staphylococcus aureus isolate 23S01467-1]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide

• Length: 975 bp

>NTDB_id=1169242 ACNUD4_RS13395 WP_000697220.1 2636605..2637579(-) (comGA) [Staphylococcus aureus isolate 23S01467-1]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTACGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGGCCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATTGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (7-267)

3D structure

• AlphaFold DB: W8U5L8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA	Staphylococcus aureus MW2	100	100	1
comGA	Staphylococcus aureus N315	100	100	1