Detailed information NTG1169222

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACNUD4_RS05280
• Genome accession: NZ_OZ197090
• Coordinates: 1061194..1062081 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus isolate 23S01467-1
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1056194..1067081

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACNUD4_RS05250	-	1056926..1057687 (+)	762	WP_000323448.1	alpha/beta hydrolase	-
ACNUD4_RS05255	-	1057932..1058387 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACNUD4_RS05260	-	1058509..1058610 (+)	102	WP_000731972.1	SE2200 family small protein	-
ACNUD4_RS05265	-	1058670..1060094 (-)	1425	WP_000953736.1	alkaline phosphatase	-
ACNUD4_RS05270	-	1060292..1060492 (+)	201	WP_000604731.1	hypothetical protein	-
ACNUD4_RS05275	braR	1060518..1061183 (+)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACNUD4_RS05280	braS	1061194..1062081 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACNUD4_RS05285	-	1062189..1062944 (+)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
ACNUD4_RS05290	-	1062941..1064941 (+)	2001	WP_000776741.1	ABC transporter permease	-
ACNUD4_RS05295	-	1065608..1065721 (+)	114	WP_014937089.1	hypothetical protein	-
ACNUD4_RS05300	-	1066103..1066363 (+)	261	WP_014937088.1	hypothetical protein	-
ACNUD4_RS05305	-	1066373..1066870 (+)	498	WP_001065267.1	glutathione peroxidase	-
ACNUD4_RS05310	-	1066978..1067070 (-)	93	WP_031774855.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=1169222 ACNUD4_RS05280 WP_000143420.1 1061194..1062081(+) (braS) [Staphylococcus aureus isolate 23S01467-1]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1169222 ACNUD4_RS05280 WP_000143420.1 1061194..1062081(+) (braS) [Staphylococcus aureus isolate 23S01467-1]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTGGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993