Detailed information NTG1169200

Bioinformatically predicted

Overview

• Name: ccrA
• Type: Machinery gene
• Locus tag: ACNUEB_RS10955
• Genome accession: NZ_OZ197089
• Coordinates: 2147475..2148824 (+)
• Length: 449 a.a.
• NCBI ID: WP_416763906.1
• Uniprot ID: -
• Organism: Staphylococcus aureus isolate 23S00080-1
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	2141868..2157239	2147475..2148824	within	0

Gene organization within MGE regions

Location: 2141868..2157239

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACNUEB_RS10935	-	2141868..2143358 (-)	1491	WP_000554504.1	RNA-binding domain-containing protein	-
ACNUEB_RS10940	-	2143976..2145025 (-)	1050	WP_000613248.1	hypothetical protein	-
ACNUEB_RS10945	ssb	2145164..2145454 (+)	291	WP_001036437.1	cassette chromosome ssDNA-binding protein	-
ACNUEB_RS10950	cch1	2145454..2147241 (+)	1788	WP_000122621.1	cassette chromosome replicative helicase	-
ACNUEB_RS10955	ccrA	2147475..2148824 (+)	1350	WP_416763906.1	cassette chromosome recombinase CcrA	Machinery gene
ACNUEB_RS10960	ccrB	2148846..2150474 (+)	1629	WP_001186604.1	cassette chromosome recombinase CcrB	Machinery gene
ACNUEB_RS10965	-	2150996..2151346 (+)	351	WP_000849672.1	SAUGI family uracil-DNA glycosylase inhibitor	-
ACNUEB_RS10970	-	2151433..2151744 (+)	312	WP_000700851.1	DUF960 family protein	-
ACNUEB_RS10975	-	2151759..2152265 (+)	507	WP_001092189.1	DUF1643 domain-containing protein	-
ACNUEB_RS10980	-	2152314..2153924 (+)	1611	Protein_2129	IS1182 family transposase	-
ACNUEB_RS10985	-	2153915..2154157 (-)	243	Protein_2130	type I restriction enzyme endonuclease domain-containing protein	-
ACNUEB_RS10990	-	2154147..2155133 (-)	987	WP_001549960.1	beta-lactam sensor/signal transducer MecR1	-
ACNUEB_RS10995	mecA	2155230..2157239 (+)	2010	WP_001801873.1	PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 52649.37 Da
• Isoelectric Point: 10.0472

>NTDB_id=1169200 ACNUEB_RS10955 WP_416763906.1 2147475..2148824(+) (ccrA) [Staphylococcus aureus isolate 23S00080-1]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYRVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYDYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRLQKQTKQTSSDNQLKQKIKCPCCNATLTNMTIRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKGAIDKRIKRQRNIEKHHILTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQRTIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIINQAMQSSIA

Nucleotide

• Length: 1350 bp

>NTDB_id=1169200 ACNUEB_RS10955 WP_416763906.1 2147475..2148824(+) (ccrA) [Staphylococcus aureus isolate 23S00080-1]
ATGAAACAAGTTATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACACAATTAATTCAACAAGGACAATGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
TTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACATATCGTGTTCATATCTTAAGTGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCGGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACCCATGCGCCCTTTGGTTACGATTATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGTCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATTGCAAAAACAAACCAAACAGACATCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCATTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAGGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACATATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATAAATGGGCATCAAATACAACGCACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCATCAATCAAGCCATGCAATCATCGATTGCATAA

Domains

Predicted by InterproScan.

• Recombinase (Recombinase) (169-248)

• Recombinase zinc beta ribbon domain (Zn_ribbon_recom) (262-321)

• Resolvase, N terminal domain (Resolvase) (4-147)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrA	Staphylococcus aureus N315	97.105	100	0.971
ccrA	Staphylococcus aureus COL	74.61	100	0.746