Detailed information NTG1169082

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACNUDR_RS11380
• Genome accession: NZ_OZ197086
• Coordinates: 2286357..2287244 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus isolate 23S01549-1
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2281357..2292244

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACNUDR_RS11350	-	2282089..2282850 (+)	762	WP_000323448.1	alpha/beta hydrolase	-
ACNUDR_RS11355	-	2283095..2283550 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACNUDR_RS11360	-	2283672..2283773 (+)	102	WP_000731972.1	SE2200 family small protein	-
ACNUDR_RS11365	-	2283833..2285257 (-)	1425	WP_000953736.1	alkaline phosphatase	-
ACNUDR_RS11370	-	2285455..2285655 (+)	201	WP_000604731.1	hypothetical protein	-
ACNUDR_RS11375	braR	2285681..2286346 (+)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACNUDR_RS11380	braS	2286357..2287244 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACNUDR_RS11385	-	2287352..2288107 (+)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
ACNUDR_RS11390	-	2288104..2290104 (+)	2001	WP_000776741.1	ABC transporter permease	-
ACNUDR_RS11395	-	2290771..2290884 (+)	114	WP_014937089.1	hypothetical protein	-
ACNUDR_RS11400	-	2291266..2291526 (+)	261	WP_014937088.1	hypothetical protein	-
ACNUDR_RS11405	-	2291536..2292033 (+)	498	WP_001065267.1	glutathione peroxidase	-
ACNUDR_RS11410	-	2292141..2292233 (-)	93	WP_031774855.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=1169082 ACNUDR_RS11380 WP_000143420.1 2286357..2287244(+) (braS) [Staphylococcus aureus isolate 23S01549-1]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1169082 ACNUDR_RS11380 WP_000143420.1 2286357..2287244(+) (braS) [Staphylococcus aureus isolate 23S01549-1]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTGGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993