Detailed information NTG1169039

Bioinformatically predicted

Overview

• Name: ccrA
• Type: Machinery gene
• Locus tag: ACNUDZ_RS13425
• Genome accession: NZ_OZ197085
• Coordinates: 2627685..2629034 (-)
• Length: 449 a.a.
• NCBI ID: WP_031775881.1
• Uniprot ID: -
• Organism: Staphylococcus aureus isolate 23S01974-1
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	2619270..2634586	2627685..2629034	within	0

Gene organization within MGE regions

Location: 2619270..2634586

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACNUDZ_RS13385	mecA	2619270..2621279 (-)	2010	WP_001801873.1	PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA	-
ACNUDZ_RS13390	-	2621376..2622362 (+)	987	WP_001549960.1	beta-lactam sensor/signal transducer MecR1	-
ACNUDZ_RS13395	-	2622352..2622594 (+)	243	Protein_2596	type I restriction enzyme endonuclease domain-containing protein	-
ACNUDZ_RS13400	-	2622585..2624195 (-)	1611	Protein_2597	IS1182 family transposase	-
ACNUDZ_RS13405	-	2624244..2624750 (-)	507	WP_001092189.1	DUF1643 domain-containing protein	-
ACNUDZ_RS13410	-	2624765..2625076 (-)	312	WP_000700851.1	DUF960 family protein	-
ACNUDZ_RS13415	-	2625163..2625513 (-)	351	WP_000849672.1	SAUGI family uracil-DNA glycosylase inhibitor	-
ACNUDZ_RS13420	ccrB	2626035..2627663 (-)	1629	WP_001186604.1	cassette chromosome recombinase CcrB	Machinery gene
ACNUDZ_RS13425	ccrA	2627685..2629034 (-)	1350	WP_031775881.1	cassette chromosome recombinase CcrA	Machinery gene
ACNUDZ_RS13430	cch1	2629268..2631055 (-)	1788	WP_000122621.1	cassette chromosome replicative helicase	-
ACNUDZ_RS13435	ssb	2631055..2631345 (-)	291	WP_001036437.1	cassette chromosome ssDNA-binding protein	-
ACNUDZ_RS13440	-	2631484..2632533 (+)	1050	WP_000613248.1	hypothetical protein	-
ACNUDZ_RS13445	-	2633096..2634586 (+)	1491	WP_000554504.1	RNA-binding domain-containing protein	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 52635.34 Da
• Isoelectric Point: 10.0472

>NTDB_id=1169039 ACNUDZ_RS13425 WP_031775881.1 2627685..2629034(-) (ccrA) [Staphylococcus aureus isolate 23S01974-1]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYRVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYDYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRLQKQTKQTSSDNQLKQKIKCPCCNATLTNMTIRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKGAIDKRIKRQRNIEKHHILTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQRTIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQAMQSSIA

Nucleotide

• Length: 1350 bp

>NTDB_id=1169039 ACNUDZ_RS13425 WP_031775881.1 2627685..2629034(-) (ccrA) [Staphylococcus aureus isolate 23S01974-1]
ATGAAACAAGTTATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACACAATTAATTCAACAAGGACAATGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
TTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACATATCGTGTTCATATCTTAAGTGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCGGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACCCATGCGCCCTTTGGTTACGATTATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGTCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATTGCAAAAACAAACCAAACAGACATCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCATTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAGGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACATATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATAAATGGGCATCAAATACAACGCACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAGCCATGCAATCATCGATTGCATAA

Domains

Predicted by InterproScan.

• Recombinase (Recombinase) (169-248)

• Recombinase zinc beta ribbon domain (Zn_ribbon_recom) (262-321)

• Resolvase, N terminal domain (Resolvase) (4-147)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrA	Staphylococcus aureus N315	97.327	100	0.973
ccrA	Staphylococcus aureus COL	74.833	100	0.748