Detailed information NTG1169029

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACNUDZ_RS09165
• Genome accession: NZ_OZ197085
• Coordinates: 1764838..1765881 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus isolate 23S01974-1
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1759838..1770881

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACNUDZ_RS09135	-	1760259..1761515 (-)	1257	WP_074347694.1	aminopeptidase	-
ACNUDZ_RS09140	-	1761518..1761718 (-)	201	WP_000180460.1	DUF1128 family protein	-
ACNUDZ_RS09145	-	1761865..1762329 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
ACNUDZ_RS09150	-	1762336..1762611 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ACNUDZ_RS09155	-	1762889..1764106 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
ACNUDZ_RS09160	vraR	1764219..1764848 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
ACNUDZ_RS09165	vraS	1764838..1765881 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACNUDZ_RS09170	liaF	1765878..1766579 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACNUDZ_RS09175	-	1766594..1766980 (-)	387	WP_001110182.1	hypothetical protein	-
ACNUDZ_RS09180	map	1767197..1767955 (-)	759	WP_000636145.1	type I methionyl aminopeptidase	-
ACNUDZ_RS09185	-	1768539..1769525 (+)	987	WP_000999712.1	FUSC family protein	-
ACNUDZ_RS09190	-	1769714..1770127 (-)	414	WP_025174370.1	hypothetical protein	-
ACNUDZ_RS09195	-	1770156..1770266 (-)	111	WP_014937049.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1169029 ACNUDZ_RS09165 WP_001017131.1 1764838..1765881(-) (vraS) [Staphylococcus aureus isolate 23S01974-1]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1169029 ACNUDZ_RS09165 WP_001017131.1 1764838..1765881(-) (vraS) [Staphylococcus aureus isolate 23S01974-1]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTTCTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAATTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAATTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1