Detailed information NTG1169014

Bioinformatically predicted

Overview

• Name: comGA
• Type: Machinery gene
• Locus tag: ACNUDZ_RS04660
• Genome accession: NZ_OZ197085
• Coordinates: 898730..899704 (+)
• Length: 324 a.a.
• NCBI ID: WP_000697220.1
• Uniprot ID: W8U5L8
• Organism: Staphylococcus aureus isolate 23S01974-1
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 893730..904704

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACNUDZ_RS04625	rpmG	894190..894339 (+)	150	WP_001265709.1	50S ribosomal protein L33	-
ACNUDZ_RS04630	-	894548..895087 (+)	540	WP_000164554.1	5-formyltetrahydrofolate cyclo-ligase	-
ACNUDZ_RS04635	-	895099..896562 (+)	1464	WP_001017856.1	rhomboid family protein	-
ACNUDZ_RS04640	-	896543..896746 (+)	204	WP_000087559.1	YqgQ family protein	-
ACNUDZ_RS04645	-	896743..897729 (+)	987	WP_000161315.1	ROK family glucokinase	-
ACNUDZ_RS04650	-	897729..898058 (+)	330	WP_001018871.1	MTH1187 family thiamine-binding protein	-
ACNUDZ_RS04655	-	898055..898678 (+)	624	WP_001223008.1	MBL fold metallo-hydrolase	-
ACNUDZ_RS04660	comGA	898730..899704 (+)	975	WP_000697220.1	competence type IV pilus ATPase ComGA	Machinery gene
ACNUDZ_RS04665	comGB	899676..900746 (+)	1071	WP_000776425.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACNUDZ_RS04670	-	900893..902063 (+)	1171	Protein_910	IS256-like element IS256 family transposase	-
ACNUDZ_RS04675	-	902130..902276 (+)	147	WP_001789879.1	hypothetical protein	-
ACNUDZ_RS04680	-	902266..902790 (+)	525	WP_001015120.1	shikimate kinase	-
ACNUDZ_RS04685	gcvT	902949..904040 (+)	1092	WP_000093349.1	glycine cleavage system aminomethyltransferase GcvT	-

Sequence

Protein

• Length: 324 a.a.
• Molecular weight: 36897.96 Da
• Isoelectric Point: 8.8516

>NTDB_id=1169014 ACNUDZ_RS04660 WP_000697220.1 898730..899704(+) (comGA) [Staphylococcus aureus isolate 23S01974-1]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide

• Length: 975 bp

>NTDB_id=1169014 ACNUDZ_RS04660 WP_000697220.1 898730..899704(+) (comGA) [Staphylococcus aureus isolate 23S01974-1]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTACGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGGCCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATTGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (7-267)

3D structure

• AlphaFold DB: W8U5L8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA	Staphylococcus aureus MW2	100	100	1
comGA	Staphylococcus aureus N315	100	100	1