Detailed information NTG1168982

Bioinformatically predicted

Overview

• Name: comGA
• Type: Machinery gene
• Locus tag: ACNUDX_RS10050
• Genome accession: NZ_OZ197084
• Coordinates: 2010258..2011232 (+)
• Length: 324 a.a.
• NCBI ID: WP_000697220.1
• Uniprot ID: W8U5L8
• Organism: Staphylococcus aureus isolate 23S01952-1
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2005258..2016232

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACNUDX_RS10015	rpmG	2005718..2005867 (+)	150	WP_001265709.1	50S ribosomal protein L33	-
ACNUDX_RS10020	-	2006076..2006615 (+)	540	WP_000164554.1	5-formyltetrahydrofolate cyclo-ligase	-
ACNUDX_RS10025	-	2006627..2008090 (+)	1464	WP_001017856.1	rhomboid family protein	-
ACNUDX_RS10030	-	2008071..2008274 (+)	204	WP_000087559.1	YqgQ family protein	-
ACNUDX_RS10035	-	2008271..2009257 (+)	987	WP_000161315.1	ROK family glucokinase	-
ACNUDX_RS10040	-	2009257..2009586 (+)	330	WP_001018871.1	MTH1187 family thiamine-binding protein	-
ACNUDX_RS10045	-	2009583..2010206 (+)	624	WP_001223008.1	MBL fold metallo-hydrolase	-
ACNUDX_RS10050	comGA	2010258..2011232 (+)	975	WP_000697220.1	competence type IV pilus ATPase ComGA	Machinery gene
ACNUDX_RS10055	comGB	2011204..2012274 (+)	1071	WP_000776425.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACNUDX_RS10060	-	2012421..2013591 (+)	1171	Protein_1972	IS256-like element IS256 family transposase	-
ACNUDX_RS10065	-	2013658..2013804 (+)	147	WP_001789879.1	hypothetical protein	-
ACNUDX_RS10070	-	2013794..2014318 (+)	525	WP_001015120.1	shikimate kinase	-
ACNUDX_RS10075	gcvT	2014477..2015568 (+)	1092	WP_000093349.1	glycine cleavage system aminomethyltransferase GcvT	-

Sequence

Protein

• Length: 324 a.a.
• Molecular weight: 36897.96 Da
• Isoelectric Point: 8.8516

>NTDB_id=1168982 ACNUDX_RS10050 WP_000697220.1 2010258..2011232(+) (comGA) [Staphylococcus aureus isolate 23S01952-1]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide

• Length: 975 bp

>NTDB_id=1168982 ACNUDX_RS10050 WP_000697220.1 2010258..2011232(+) (comGA) [Staphylococcus aureus isolate 23S01952-1]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTACGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGGCCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATTGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (7-267)

3D structure

• AlphaFold DB: W8U5L8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA	Staphylococcus aureus MW2	100	100	1
comGA	Staphylococcus aureus N315	100	100	1