Detailed information NTG1168913

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACNUD3_RS12535
• Genome accession: NZ_OZ197082
• Coordinates: 2547211..2548098 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus isolate 23S00051-1
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2542211..2553098

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACNUD3_RS12505	-	2542943..2543704 (+)	762	WP_000323448.1	alpha/beta hydrolase	-
ACNUD3_RS12510	-	2543949..2544404 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACNUD3_RS12515	-	2544526..2544627 (+)	102	WP_000731972.1	SE2200 family small protein	-
ACNUD3_RS12520	-	2544687..2546111 (-)	1425	WP_000953736.1	alkaline phosphatase	-
ACNUD3_RS12525	-	2546309..2546509 (+)	201	WP_000604731.1	hypothetical protein	-
ACNUD3_RS12530	braR	2546535..2547200 (+)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACNUD3_RS12535	braS	2547211..2548098 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACNUD3_RS12540	-	2548206..2548961 (+)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
ACNUD3_RS12545	-	2548958..2550958 (+)	2001	WP_000776741.1	ABC transporter permease	-
ACNUD3_RS12550	-	2551625..2551738 (+)	114	WP_014937089.1	hypothetical protein	-
ACNUD3_RS12555	-	2552120..2552380 (+)	261	WP_014937088.1	hypothetical protein	-
ACNUD3_RS12560	-	2552390..2552887 (+)	498	WP_001065267.1	glutathione peroxidase	-
ACNUD3_RS12565	-	2552995..2553087 (-)	93	WP_031774855.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=1168913 ACNUD3_RS12535 WP_000143420.1 2547211..2548098(+) (braS) [Staphylococcus aureus isolate 23S00051-1]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1168913 ACNUD3_RS12535 WP_000143420.1 2547211..2548098(+) (braS) [Staphylococcus aureus isolate 23S00051-1]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTGGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993